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Richard A. Amos, CPhys, CSci, FIPEM

@protontherapy.bsky.social
534 followers 117 following 79 posts

Professor of Particle Therapy Physics | Chartered Physicist | Chartered Scientist | Gymnastics Dad | #MedPhys scholar.google.com/citations?user=9…

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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 08/06/2026
En route to Deauville, France for #PTCOG64. See you there…..
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 05/06/2026
med.stanford.edu/news/all-new...
med.stanford.edu
7-year-old is the first to receive proton therapy at Stanford Medicine
Stanford Medicine’s new proton therapy facility is ready for patients. On June 4 a child with a rare brain tumor became the first to receive treatment.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 29/05/2026
ESTRO debate reveals rising confidence in upright proton therapy physicsworld.com/a/estro-deba...
physicsworld.com
ESTRO debate reveals rising confidence in upright proton therapy – Physics World
A lively debate at the ESTRO 2026 meeting concluded with nearly 70% of the audience backing upright proton therapy as a mainstream treatment option by 2035
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 21/05/2026
Tony Lomax joins RaySearch. www.raysearchlabs.com/media/press-...
raysearchlabs.com
Antony Lomax joins RaySearch to strengthen leadership in particle therapy | RaySearch Laboratories
<div class="mfn-preamble"><p><strong>RaySearch Laboratories AB (publ) appoints Professor Antony Lomax, one of the world’s most respected pioneers in p
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 17/05/2026
Proton versus photon therapy for oropharyngeal cancer | The Lancet www.thelancet.com/journals/lan...
thelancet.com
Proton versus photon therapy for oropharyngeal cancer
Trials of local therapies where progression-free survival is equivalent but overall survival is improved raise the spectre of confounding. The overall survival improvement seen in the phase 3 trial by...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 07/11/2025
Comparison of protons and very high-energy electrons transmission pencil-beam-scanning for FLASH radiotherapy www.sciencedirect.com/science/arti...
sciencedirect.com
Comparison of protons and very high-energy electrons transmission pencil-beam-scanning for FLASH radiotherapy
Very High-Energy Electron (VHEE) radiotherapy stands as a promising alternative to proton therapy in view of the FLASH effect, which allows for differ…
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 20/10/2025
Call for members: For those of you involved in particle therapy physics across Europe and beyond, please consider joining the EFOMP Particle Therapy Special Interest Group (SIG). Link to join here: www.efomp.org/index.php?r=... #MedPhys
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 12/10/2025
Head Neck Cancer: TORPEdO dropped! IMRT vs. Protons, Round 2. open.substack.com/pub/protons1...
open.substack.com
Head and Neck: TORPEdO dropped! IMRT vs. Protons. Our second RCT trial!
Now two trials with different conclusions?? What can we learn?
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 17/08/2025
New Radiation Cancer Facility Opens. Radiation Oncology throws stones. open.substack.com/pub/protons1...
open.substack.com
New Radiation Cancer Facility Opens. Radiation Oncology throws stones.
What's worse than the Death Star of medicine? A carbon ion Death Star. At least if you listen to our own field.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 14/08/2025
Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus - International Journal of Radiation Oncology, Biology, Physics www.redjournal.org/article/S036...
redjournal.org
Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus
The FLASH effect, defined as normal tissue sparing while maintaining tumor control with ultra-high dose-rate irradiation, has been demonstrated preclinically in different tumors and tissues. Although ...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 12/08/2025
A Case of Hydrogel Spacer Intravasation of the Internal Iliac Vein and Associated Thrombus Formation During Preparation for Prostate Cancer External Beam Radiation Therapy - Practical Radiation Oncology www.practicalradonc.org/article/S187...
practicalradonc.org
A Case of Hydrogel Spacer Intravasation of the Internal Iliac Vein and Associated Thrombus Formation During Preparation for Prostate Cancer External Beam Radiation Therapy
Use of rectal spacer gel has been associated with decreased risk of radiation therapy (RT)-related rectal toxicity in clinical trials and has been increasingly adopted. Optimal management of spacer-re...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 30/07/2025
It was a pleasure to be organizer and speaker today at the Joint AAPM/EFOMP Session on Particle Therapy at #AAPM2025 @aapmhq.bsky.social
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 12/07/2025
It was a pleasure to contribute to a successful ESMPE School for Proton Therapy Physics as Scientific Chair and Lecturer these last few days in Prague. #ESMPE #EFOMP
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 02/07/2025
Dose heterogeneity reduces radiation oxygen dependence in both tumor and healthy tissues: the case of proton minibeam radiation therapy. www.redjournal.org/article/S036...
redjournal.org
Dose heterogeneity reduces radiation oxygen dependence in both tumor and healthy tissues: the case of proton minibeam radiation therapy
Proton minibeam radiation therapy (pMBRT) is an innovative delivery technique characterized by spatially modulated radiation. It was shown to increase the therapeutic index in preclinical glioma model...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 13/06/2025
Proton therapy comes to Dubai. www.arnnewscentre.ae/en/news/uae/...
arnnewscentre.ae
Dubai advances cancer care with first proton therapy centre
The UAE’s first proton therapy centre will be built in Dubai, marking a major step forward in cancer treatment in the region.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 12/06/2025
Team LhARA at the Great Exhibition Road Festival. (I was not able to join the team as I was attending a conference elsewhere). #LhARA #GERF
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 01/06/2025
En route to Buenos Aires, Argentina for PTCOG63. Who else will be there? #PTCOG63
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 14/05/2025
Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source: www.nature.com/articles/s41...
nature.com
Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source - Scientific Reports
Scientific Reports - Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 13/05/2025
Implementation of a novel pencil beam scanning Bragg peak FLASH technique to a commercial treatment planning system aapm.onlinelibrary.wiley.com/doi/full/10....
aapm.onlinelibrary.wiley.com
<em>Medical Physics</em> | AAPM Journal | Wiley Online Library
Background Ultra-high dose rate, or FLASH, radiotherapy has shown promise in preclinical experiments of sparing healthy tissue without compromising tumor control. This “FLASH effect” can compound wi...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 21/04/2025
Houston will be hit hardest': Researchers in Texas Medical Center brace for impact of Trump NIH cuts www.khou.com/article/news...
khou.com
'Houston will be hit hardest': Researchers in Texas Medical Center brace for impact of Trump NIH cuts
TMC could lose millions of dollars in NIH funding raising the threat of job cuts. A legal battle is now expected to end up in the Supreme Court.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 18/04/2025
Radiation oncology patients’ perceptions of artificial intelligence and machine learning in cancer care: A multi-centre cross-sectional study www.sciencedirect.com/science/arti...
sciencedirect.com
Radiation oncology patients’ perceptions of artificial intelligence and machine learning in cancer care: A multi-centre cross-sectional study
The use of artificial intelligence (AI) and machine learning (ML) is increasingly widespread in radiation oncology. However, patient engagement to dat…
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 16/04/2025
Very high-energy electrons could prove optimal for FLASH radiotherapy physicsworld.com/a/very-high-...
physicsworld.com
Very high-energy electrons could prove optimal for FLASH radiotherapy – Physics World
THERYQ is developing a radiotherapy system that uses very high-energy electrons to treat deep-seated tumours, and can also enable FLASH treatments
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 15/04/2025
FLASH Workshop 2025: The Role of Oxygen in FLASH Radiation Therapy www.dkfz.de/en/biomedica...
dkfz.de
FLASH Workshop 2025: The Role of Oxygen in FLASH Radiation Therapy - German Cancer Research CenterLogo des Deutschen KrebsforschungszentrumsLogo of the German Cancer Research CenterLogo of the German ...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 15/04/2025
HOW UPRIGHT POSITIONING IS SHAPING THE FUTURE OF PROTON THERAPY blog.mevion.com/en/blog/how-...
blog.mevion.com
How Upright Positioning is Shaping the Future of Proton Therapy
Proton therapy is undergoing a revolutionary transformation with the advent of upright patient positioning, promising improved precision and comfort in cancer treatment.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 01/04/2025
Requirements and study design for the next proton FLASH clinical trials: an international multidisciplinary Delphi consensus @ijrobp.bsky.social www.redjournal.org/article/S036...
redjournal.org
Requirements and study design for the next proton FLASH clinical trials: an international multidisciplinary Delphi consensus
Purpose: The FLASH effect, defined as normal tissue sparing while maintaining tumor control with ultra-high dose rate (UHDR) irradiation, has been demonstrated preclinically in different tumors and ti...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 28/03/2025
www.nature.com/articles/s41...
nature.com
Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats - Scientific Reports
Scientific Reports - Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 19/03/2025
Very much enjoyed giving an invited talk today at the 3rd International Particle Minibeam Therapy (PMBT) Workshop at the National Physical Laboratory (NPL) in the UK. Photo shows a clone of Newton’s apple tree in the grounds of NPL. 🍎 #PMBT2025
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 19/03/2025
Nice to be appreciated…. @ioppublishing.bsky.social
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 14/03/2025
IPEM Reacts to Decision to Abolish NHS England - @ipemnews.bsky.social www.ipem.ac.uk/news/ipem-re...
ipem.ac.uk
IPEM Reacts to Decision to Abolish NHS England
IPEM has released a statement in response to the Government's decision to abolish NHS England
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 13/03/2025
IPEM code of practice for proton therapy dosimetry based on the NPL primary standard proton calorimeter calibration service. iopscience.iop.org/article/10.1... @ioppublishing.bsky.social @ipemnews.bsky.social @aapmhq.bsky.social
iopscience.iop.org
IPEM code of practice for proton therapy dosimetry based on the NPL primary standard proton calorimeter calibration service - IOPscienceSearch
IPEM code of practice for proton therapy dosimetry based on the NPL primary standard proton calorimeter calibration service, Green, Stuart, Lourenço, Ana, Palmans, Hugo, Lee, Nigel, Amos, Richard A, Souza, Derek D’, Fiorini, Francesca, Van Den Heuvel, Frank, Kacperek, Andrzej, Mackay, Ranald, Pettingell, John, Thomas, Russell
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 06/03/2025
Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model www.nature.com/articles/s41...
nature.com
Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model - Scientific Reports
Scientific Reports - Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 26/02/2025
Houston’s MD Anderson, Texas Children’s Hospital announce collaboration to combat childhood cancer www.houstonpublicmedia.org/articles/new...
houstonpublicmedia.org
Houston’s MD Anderson, Texas Children’s Hospital announce collaboration to combat childhood cancer | Houston Public Media
MD Anderson says the collaborative, set to begin in 2026, will combine the two institutions’ patient populations to “increase pediatric cancer clinical trials.”
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 26/02/2025
Trump 2.0: an assault on science anywhere is an assault on science everywhere www.nature.com/articles/d41...
nature.com
Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 26/02/2025
Towards an adequate description of the dose-response relationship in BNCT of glioblastoma multiforme aapm.onlinelibrary.wiley.com/doi/10.1002/...
aapm.onlinelibrary.wiley.com
<em>Medical Physics</em> | AAPM Journal | Wiley Online Library
Background Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy based on the intravenous administration of a borated drug to the patient and the subsequent irradiation with a low-energy neu...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 24/02/2025
Aberrant choroid plexus formation drives the development of treatment-related brain toxicity www.nature.com/articles/s42...
nature.com
Aberrant choroid plexus formation drives the development of treatment-related brain toxicity - Communications Biology
Human cerebral organoids provide insights into mechanisms behind the formation of choroid plexus (CP)-like structures that may contribute to radiation-induced brain image changes.
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 16/02/2025
FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy www.nature.com/articles/s43...
nature.com
FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy - Nature Cancer
Fan and colleagues show that FLASH radiation promotes proinflammatory polarization of tumor-associated macrophages, which in turn increases T cell influx in medulloblastoma and synergizes with CAR-T c...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 12/02/2025
On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy www.thegreenjournal.com/article/S016...
thegreenjournal.com
On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy
Proton minibeam radiation therapy (pMBRT) [1] is a type of spatially fractionated radiation therapy (SFRT) [2], which uses submillimetric (0.5–1.0 mm) proton beams spaced by 1.0 to 4.0 mm. The dose pr...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 10/02/2025
Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI www.biorxiv.org/content/10.1...
biorxiv.org
Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI
Background and purpose: The FLASH effect expands the therapeutic ratio of tumor control to normal tissue toxicity observed after delivery of ultra-high (>100 Gy/s FLASH-RT) vs. conventional dose rate ...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 08/02/2025
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy - Manjit Dosanjh, Alberto Degiovanni, Maria Monica Necchi, Elena Benedetto, 2025
The battle against cancer remains a top priority for society, with an urgent need to develop therapies capable of targeting challenging tumours while preserving...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 06/02/2025
FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy www.nature.com/articles/s43...
nature.com
FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy - Nature Cancer
Fan and colleagues show that FLASH radiation promotes proinflammatory polarization of tumor-associated macrophages, which in turn increases T cell influx in medulloblastoma and synergizes with CAR-T c...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 04/02/2025
LET measurements and simulation modelling of the charged particle field for the Clatterbridge ocular proton therapy beamline arxiv.org/abs/2501.17404
arxiv.org
LET measurements and simulation modelling of the charged particle field for the Clatterbridge ocular proton therapy beamline
Proton therapy can achieve a highly targeted treatment by utilising the advantageous dosimetric characteristics of the Bragg Peak. Protons traversing through a material will deposit their maximum ener...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 04/02/2025
Microbeams plus radiosensitizers could optimize brain cancer treatment physicsworld.com/a/microbeams...
physicsworld.com
Microbeams plus radiosensitizers could optimize brain cancer treatment – Physics World
Combining microbeam radiotherapy with targeted radiosensitizers could treat tumours while sparing normal brain tissues
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 03/02/2025
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy - Manjit Dosanjh, Alberto Degiovanni, Maria Monica Necchi, Elena Benedetto, 2025
The battle against cancer remains a top priority for society, with an urgent need to develop therapies capable of targeting challenging tumours while preserving...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 29/01/2025
University of Cape Town to launch proposed proton therapy centre: www.iol.co.za/weekend-argu...
iol.co.za
UCT to launch proposed proton therapy centre to boost cancer treatment
A multidisciplinary team at the University of Cape Town (UCT) is poised to make significant advancements in cancer treatment by designing a proton therapy centre in Cape Town, aimed at serving both th...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 25/01/2025
Stable laser-acceleration of high-flux proton beams with plasma collimation. www.nature.com/articles/s41...
nature.com
Stable laser-acceleration of high-flux proton beams with plasma collimation - Nature Communications
Applications of laser-plasma accelerated protons in fundamental, applied and medical sciences crucially depend on the creation of stable collimated beams with high repetition rates. Here the authors d...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 23/01/2025
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring | Science | AAAS www.science.org/content/arti...
science.org
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 22/01/2025
IPEM code of practice for proton therapy dosimetry based on the NPL primary standard proton calorimeter calibration service: iopscience.iop.org/article/10.1...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 20/01/2025
Whole Abdominal Pencil Beam Scanned Proton FLASH Increases Acute Lethality - International Journal of Radiation Oncology, Biology, Physics www.redjournal.org/article/S036...
redjournal.org
Whole Abdominal Pencil Beam Scanned Proton FLASH Increases Acute Lethality
Ultrahigh dose-rate FLASH radiation therapy has emerged as a modality that promises to reduce normal tissue toxicity while maintaining tumor control. Previous studies of gastrointestinal toxicity usin...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 05/01/2025
Proton Beam Therapy for Pancreatic Tumors: A Consensus Statement from the Particle Therapy Cooperative Group Gastrointestinal Subcommittee: www.redjournal.org/article/S036...
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Richard A. Amos, CPhys, CSci, FIPEM @protontherapy.bsky.social · 30/12/2024
UCL in 2024: A year of innovation and impact. @uclofficial.bsky.social www.ucl.ac.uk/news/2024/de...
ucl.ac.uk
UCL in 2024: A year of innovation and impact
In the last year UCL’s staff, students and alumni have continued to change the world with their research, innovation and achievements. From making key discoveries in dementia and cancer research, to b...
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