iiinova — where your digital self keeps evolving

Protea Glycosciences @proteaglyco.bsky.social · 30/04/2026

Here’s one public aspect of our cutting edge methods for glycan and polysaccharide detection. The result: more confident characterisation leading to more successful projects.

000

Protea Glycosciences @proteaglyco.bsky.social · 13/04/2026

🧵 We published GlyCombo in 2024 and it's still one of my favourite things we've built. Here's what it actually does and why it matters for glycomics labs. (1/4) #glycotime

110

Reposted by Protea Glycosciences

Chris Ashwood @cashwood.proteaglyco.com · 22/12/2025

Closing out the year at @proteaglyco.bsky.social with real momentum. We advanced native glycomics to reveal often-missed labile modifications, and saw global uptake of our GlyCombo software. Huge thanks to our team and collaborators, building towards an even more accelerated, high-impact 2026.

A man sitting at a liquid chromatograph and mass spectrometer used for glycan analaysis.

0221

Reposted by Protea Glycosciences

Chris Ashwood @cashwood.proteaglyco.com · 05/02/2026

On my way to Lorne, Australia for #LorneProteomics2026. Looking forward to seeing the latest proteomics and glycomics advances. I’ll be presenting our glycomics platform that more truthfully describes the glycome resulting in greater glycopeptide identifications. Happy to meet up if you’re there!

1151

Protea Glycosciences @proteaglyco.bsky.social · 20/10/2025

Keen to share our latest work where we apply our native PGC-LC-MS glycan analysis workflow and see what is missed with traditional glycomics workflows (reduction or permethylation) Here, we found intact O-acetylation of sialic acids on N-glycans in mouse and rat sera www.biorxiv.org/content/10.1...

biorxiv.org

Native PGC-LC-MS Profiling Reveals Distinct O-Acetylation Patterns of Sialylated N-Glycans Across Mammalian Sera

O-acetylation of sialic acids represents an additional layer of structural diversity and biological complexity, occurring at various hydroxyl positions (commonly C-7, C-8, or C-9) of the sialic acid r...

192

Protea Glycosciences @proteaglyco.bsky.social · 23/05/2025

#ausomics was a great opportunity for Protea Glycosciences to share our recent advances in Glycomics and glycoproteomics and see the latest research across four Australian societies including @ozglyco.bsky.social. It was a productive conference and now we're looking forward to getting back to work.

Chris Ashwood presenting a glycoproteomics platform that is isomer-focused.

Maia Kelly presenting GlyComboCLI, a bioinformatic tool for matching glycan compositions to MS2

011

Protea Glycosciences @proteaglyco.bsky.social · 01/04/2025

Proud to announce our business relocation, our local beach. We’re committed to accelerating glycoscience, so where better to be based than a location where the glycans come to us. Our LC-MS service engineers are excited for the opportunities provided by this new location.

Protea Glycosciences new business location, a beach full of seaweed.

001

Reposted by Protea Glycosciences

Chris Ashwood @cashwood.proteaglyco.com · 31/03/2025

Excited to be presenting @proteaglyco.bsky.social's glycoproteomics workflow at Aus-Omics on Monday at the New Technologies session. We're bringing structure back to how we identify and report glycopeptides, plus we'll describe how our unique approach to glycan structure excels for glycopeptides.

AUS-oMicS May 18-25, 2025.
Abstract title: Resolving glycopeptide structural ambiguity: A new MS workflow enables definitive glycoprotein characterization

0141

Protea Glycosciences @proteaglyco.bsky.social · 24/03/2025

We're just completing an R&D sprint to identify an LC additive that increases our glycan identifications 3x and enhances glycan charge states by up to 45%🚀. It's too early to publicly disclose its identity, but here's a results preview. Interested? Message or email us, we'd love to collaborate.

Manuscript figure describing our method for evaluating mobile phase additives for enhanced negative mode LC-MS of glycans. The results show different O-glycan compositions having up to 40% higher charge states.
Interested in how our platform can help you discover more from your samples? Email us at info@proteaglyco.com to collaborate.

041

Protea Glycosciences @proteaglyco.bsky.social · 03/02/2025

Our pure glycan structures provide essential tools for researchers in glycomics, diagnostics, and therapeutic development. Partner with us to accelerate your glycan-based discoveries! #Glycobiology #TeamMassSpec #Biopharma #Diagnostics (P.S. NeuGc structures coming soon!) proteaglyco.com/shop/

proteaglyco.com

Shop - Protea Glycosciences

We are a glycoscience company established in 2023 with the aim of accelerating glycoscience research.

011

Protea Glycosciences @proteaglyco.bsky.social · 24/01/2025

Want to work with mass-based glycan data? Try out GlyCombo, our published, freely available software that rapidly assigns monosaccharide combinations to glycan masses. Here's a 5 min video showing you how to get started. Publication: pubs.acs.org/doi/10.1021/... Download: github.com/Protea-Glyco...

youtube.com

GlyCombo Quick Start Tutorial

YouTube video by Protea Glycosciences

032