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PICKED Project

@projectpicked.bsky.social
20 followers 12 following 109 posts

Advancing personalized medicine in chronic kidney disease through interdisciplinary research and innovation. #CKD #Healthcare #Research

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PICKED Project @projectpicked.bsky.social · 22/09/2026
🔬 The PICKED network met in Tallinn to share research progress and explore biomarkers, computational modelling, treatment response, entrepreneurship and patenting. 📖 Read more: lnkd.in/ec4-6iCv #PICKEDProject #KidneyResearch #PersonalisedMedicine #MSCA
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PICKED Project @projectpicked.bsky.social · 10/09/2026
We are heading to Tallinn on 16–17 September 2026 The meeting will bring together Doctoral Candidates, supervisors and invited experts. Read more: 🔗 www.projectpicked.eu/news-and-eve... #MSCA #KidneyResearch #PersonalisedMedicine #HorizonEurope
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News and Events
Stay updated with the latest news, events, and milestones from the PICKED Project as we advance personalized kidney care through research.
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PICKED Project @projectpicked.bsky.social · 09/09/2026
Congrats to Julia Byrska, who received the Cecil Alport Gold Award for Best Presentation at the 2026 International Workshop on Alport Syndrome in Budapest. 🏅 A fantastic recognition for her work on a urinary peptidomic classifier for Alport syndrome. #AlportSyndrome #KidneyResearch #MSCA
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PICKED Project @projectpicked.bsky.social · 08/09/2026
Julia Byrska presented her work on a urinary peptidomic classifier for the non-invasive diagnosis of Alport syndrome at the 2026 International Workshop on Alport Syndrome in Budapest. Read more: 🔗 www.projectpicked.eu/news-and-eve... #AlportSyndrome #Peptidomics #KidneyResearch #MSCA
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PICKED Project @projectpicked.bsky.social · 03/09/2026
Meet Eduardo Galaricha, our newest PICKED Doctoral Candidate. He combines bioinformatics, machine learning, and multi-omics data to improve prediction and patient stratification in acute kidney injury. More: 🔗 www.projectpicked.eu/doctoral-can... #Bioinformatics #MultiOmics #KidneyResearch #MSCA
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PICKED Project @projectpicked.bsky.social · 01/09/2026
New research from RD-Néphrologie, including PICKED Doctoral Candidate Siavash Sohan Gir, explores automatic blood recirculation monitoring during haemodialysis. Read more: 🔗 www.projectpicked.eu/publications... #PICKEDproject #Dialysis #KidneyResearch #Nephrology
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Publications and Results
Explore the latest publications and results from the PICKED Project, showcasing advancements in personalized kidney care and groundbreaking research.
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PICKED Project @projectpicked.bsky.social · 27/08/2026
Is chronic kidney disease different in children? Paediatric CKD is often linked to developmental disorders such as CAKUT, rather than diabetes or hypertension. That is why children need age-specific biomarkers, risk models, and treatment strategies. #PaediatricNephrology #CKD #KidneyResearch
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PICKED Project @projectpicked.bsky.social · 25/08/2026
Can personalised medicine be truly personalised if access is unequal? Advanced diagnostics, biomarkers and digital tools may not be equally available to every patient. #PersonalisedMedicine #HealthEquity #KidneyResearch #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 18/08/2026
Finding a biomarker is only the beginning. Before it can support clinical decisions, it must be measured reliably, validated in patients, independently tested, and shown to improve care. #Biomarkers #KidneyResearch #PrecisionMedicine #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 06/08/2026
Personalised real time dialysis? PICKED is exploring optical monitoring of spent dialysate to track uremic peptide removal during treatment. This could support more individualised dialysis prescriptions and provide clinicians with immediate feedback. #Dialysis #KidneyResearch #PersonalisedMedicine
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PICKED Project @projectpicked.bsky.social · 04/08/2026
Can acute kidney injury have long-term consequences? Even when kidney function appears to recover, inflammation, incomplete tissue repair, or fibrosis may persist and increase the risk of CKD. #AKI #CKD #KidneyResearch #Biomarkers #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 30/07/2026
Why are urine samples so valuable in kidney research? They can be collected non-invasively, repeatedly, and contain peptides, proteins and other molecular signals linked to kidney damage, inflammation and treatment response. #KidneyResearch #Biomarkers #Peptidomics
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PICKED Project @projectpicked.bsky.social · 28/07/2026
Doctoral Candidate Julia Byrska presented her research on urinary peptide biomarkers for the non-invasive diagnosis of Alport syndrome at the 8th Cardiovascular, Renal and Metabolic Diseases Area Meeting. Read more: 🔗 www.projectpicked.eu/news-and-eve... #KidneyResearch #AlportSyndrome #Biomarkers
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PICKED Project @projectpicked.bsky.social · 23/07/2026
What is kidney reserve? Healthy nephrons can compensate for early kidney damage, keeping eGFR normal even while disease progresses. This is why researchers are developing biomarkers to detect damage earlier and improve personalised care. #KidneyHealth #CKD #Biomarkers #EarlyDetection
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PICKED Project @projectpicked.bsky.social · 21/07/2026
The PICKED Doctoral Candidates have launched a peer-led Journal Club to discuss recent research, exchange ideas, and strengthen collaboration across Europe. Read more: 🔗 www.projectpicked.eu/news-and-eve... #PICKEDproject #MSCA #KidneyResearch #JournalClub #HorizonEurope
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PICKED Project @projectpicked.bsky.social · 16/07/2026
Why can albuminuria appear before eGFR falls? Kidney damage often starts before eGFR declines. Albuminuria, small amounts of albumin in urine, can be an early sign that the kidney's filtration barrier is already under stress. #CKD #Albuminuria #KidneyHealth #PrecisionMedicine #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 13/07/2026
PICKED Doctoral Candidate Jeremy Power presented at a UNESCO Chair symposium in Toulouse on how AI is reshaping personalised medicine from a clinical ethics perspective. 📖 Read more: www.projectpicked.eu/news-and-eve... #PICKEDproject #AI #PersonalisedMedicine #ClinicalEthics
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PICKED Project @projectpicked.bsky.social · 08/07/2026
New PICKED-related publication in NDT 🔬 Julia Byrska and colleagues explore how biological age, estimated from remaining life expectancy, may help explain the burden of kidney failure beyond chronological age alone. 📖 Read more: academic.oup.com/ndt/article-... #CKD #KidneyResearch #Nephrology
academic.oup.com
The burden of kidney failure requiring kidney replacement therapy explained by estimating biological age from remaining life expectancy
To the Editor,
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PICKED Project @projectpicked.bsky.social · 07/07/2026
CKD often develops silently. Early detection can help identify kidney disease before major damage occurs, allowing earlier treatment and better prediction of progression. That means fewer complications and better outcomes for patients. #CKD #EarlyDetection #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 02/07/2026
Two patients can have the same kidney disease but respond very differently to the same treatment. Why? CKD is biologically diverse. Personalised medicine aims to match treatment to the patient, not just the diagnosis. #CKD #PrecisionMedicine #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 30/06/2026
Kidney fibrosis is the build-up of scar tissue after kidney injury. Over time, it can reduce kidney function and drive CKD progression. By detecting fibrosis-related changes earlier, biomarkers may help predict outcomes and support treatments targeting the underlying biology. #CKD #KidneyFibrosis
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PICKED Project @projectpicked.bsky.social · 25/06/2026
Kidney disease and heart disease are closely connected. CKD increases cardiovascular risk, while heart disease can damage the kidneys. Understanding these links is key to personalised medicine. #CKD #CardiovascularDisease #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 23/06/2026
🔬 DC Sheila Murunga presented her work on biomarker-based risk prediction and biological stratification in pediatric CKD at the ESCAPE Network Meeting (11–12 June 2026, Heidelberg). 📖 Read more: www.projectpicked.eu/news-and-eve... #CKD #KidneyResearch #PrecisionMedicine #ESCAPENetwork
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PICKED Project @projectpicked.bsky.social · 09/06/2026
CKD is not one-size-fits-all. Patients may share similar kidney numbers, but differ in causes, risks, biology, symptoms, and treatment response. Personalised medicine aims to make kidney care more precise, targeted, and patient-centred. #CKD #PersonalisedMedicine #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 05/06/2026
PICKED at ERA 2026 in Glasgow 🔬 Julia Byrska and Abukayo M will present their work through oral and poster presentations at the 63rd ERA Congress. Great to see PICKED research represented at ERA! #ERA2026 #CKD #PICKEDproject #KidneyResearch
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Reposted by PICKED Project
Delta4 @delta4ai.bsky.social · 18/05/2026
#Delta4's Enrico presented his poster at the #YSA Symposium 2026 at the Medical University of Vienna. His work on systems-biological modeling of the #AKI-to-#CKD transition was selected for Session V (Regeneration & Transplantation) and sparked lively scientific discussion. #TranslationalResearch
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PICKED Project @projectpicked.bsky.social · 03/06/2026
Urine can tell us more than standard kidney markers alone. Peptidomics studies small protein fragments in urine that may reflect tissue damage, inflammation, fibrosis, progression, or treatment response. Another layer for more personalised CKD care. #CKD #Peptidomics #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 02/06/2026
In CKD, “high risk” is not just one kidney function number. Two patients can have the same eGFR but very different outlooks depending on albuminuria, blood pressure, diabetes, biomarkers, genetics, and disease history. Better risk prediction means better timing and care. #CKD #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 28/05/2026
A promising biomarker is only the beginning. Before it can guide patient care, it must be validated across cohorts, labs, and real clinical settings. That takes time, and it should. Validation protects patients and turns research into real impact. #CKD #Biomarkers #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 19/05/2026
Kidney research does not automatically become better patient care. Between discovery and real-world use lies the implementation gap: validation, regulation, reimbursement, data protection, workflows, and proof of impact. Closing that gap is how research becomes real benefit. #CKD #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 12/05/2026
Uremic toxins are more than urea. In CKD, different toxins can accumulate, some easier to remove, others harder and linked to inflammation, symptoms, or cardiovascular risk. Personalised kidney care means looking beyond one number. #CKD #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 07/05/2026
PICKED at the ERKNet Annual Meeting 2026 in Lyon, with Jeremy Power and Sheila Murunga representing their work within the project. A valuable opportunity for exchange, networking, and connecting personalised kidney care research with the rare kidney disease community. #PICKEDproject #ERKNet #CKD
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PICKED Project @projectpicked.bsky.social · 30/04/2026
CKD care can’t be only lab numbers (eGFR, creatinine, K+). Two patients with similar labs can feel very different, fatigue, itch, sleep issues, cramps, brain fog, mood. QoL is a core outcome: track symptoms + shared decisions. #CKD #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 28/04/2026
DC Spotlight 🌟 Enrico Bono: building a network-based in silico model of the AKI→CKD transition to prioritise biomarkers/targets and identify drug repurposing opportunities. Read: www.projectpicked.eu/news-and-eve... #PICKEDproject #AKI #CKD #SystemsBiology
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PICKED Project @projectpicked.bsky.social · 23/04/2026
Endothelial dysfunction = the blood vessel lining stops working well (↓ vasodilation, ↑ permeability/inflammation/clotting). In CKD this helps explain why kidney risk and cardiovascular risk travel together, often reflected by albuminuria too. #CKD #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 21/04/2026
Creatinine can mislead. Muscle mass, meat/creatine, exercise, dehydration, and some meds can shift it without true GFR change. Look at trends + uACR (± cystatin C). #CKD #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 16/04/2026
DC Spotlight 🌟 Sheila Murunga (PICKED): recruiting & collecting samples for the validation cohort, strengthening findings from the 4C cohort and moving toward biological stratification in paediatric CKD. Read: www.projectpicked.eu/news-and-eve... #PICKEDproject #CKD #Biomarkers
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PICKED Project @projectpicked.bsky.social · 14/04/2026
Hematuria = blood in urine, but where it comes from matters. Glomerular (kidney filter) → dysmorphic red blood cells (RBCs) / RBC casts. Urologic (downstream) → round, normal RBCs. Microscopy adds meaning. #CKD #Hematuria #KidneyHealth #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 09/04/2026
How do we protect patient data in personalised medicine, not just today, but in 10 years? 🔒 Privacy by design: minimise data, limit purpose, pseudonymise + control access, secure by default, be transparent. And yes, plan for a post-quantum future. #PICKEDproject #DataProtection #PrivacyByDesign
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PICKED Project @projectpicked.bsky.social · 07/04/2026
What does “early detection” mean in CKD? Not symptoms, molecular/structural damage starts first. That’s why simple routine checks (eGFR + albuminuria) + biomarkers matter: detect risk early, act sooner. #CKD #KidneyHealth #EarlyDetection #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 31/03/2026
Great discussions at the #PICKED webseminars 👏 9 DC presentations, strong supervisor feedback, and real cross-project exchange. More: www.projectpicked.eu/news-and-eve... Next up: Tallinn (15–16 Sept) #HorizonEU #MSCA #RareDiseases
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PICKED Project @projectpicked.bsky.social · 19/03/2026
Kidney screening & awareness in Agde 🇫🇷 On World Kidney Day, Jeremy Power supported NDSG’s supermarket stand, reminding people CKD can be silent and early tests (urine dipstick + creatinine) matter. Read more: www.projectpicked.eu/news-and-eve... #KidneyHealth #CKD #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 17/03/2026
Who benefits from personalised medicine? ⚖️ Precision only helps if it’s accessible and fair. #PICKEDproject #Ethics #HealthEquity
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PICKED Project @projectpicked.bsky.social · 12/03/2026
World Kidney Day 2026 🌍🩺 Kidney Health for All. Prevention. Early detection. Better outcomes. #WKD2026 #KidneyHealthForAll #CKD #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 10/03/2026
DC Spotlight 🌟 Cansenem Özkan (BRFAA, PICKED) Validating urinary & plasma protein biomarkers to predict CKD progression and monitor treatment response using multiplex mass spectrometry + peptide “signatures”. #PICKEDproject #CKD #Biomarkers
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PICKED Project @projectpicked.bsky.social · 05/03/2026
🩹🫘 Fibrosis in kidney disease = scarring. Repeated injury → “repair patch” → scar tissue replaces healthy tissue. Scar tissue can’t filter blood → higher CKD progression risk. #CKD #Fibrosis #KidneyHealth #Biomarkers #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 03/03/2026
🌟 DC Spotlight: Jeremy Power (Université de Toulouse) Prenatal CAKUT: how uncertainty affects counselling & decisions. Secondment: RD Nephrologie (Montpellier). #PICKEDproject #CAKUT #PrenatalDiagnosis #Ethics #KidneyHealth
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PICKED Project @projectpicked.bsky.social · 27/02/2026
eGFR = kidney function estimate Not a direct readout of kidney damage You can have normal/stable eGFR while inflammation, fibrosis, or tubular injury progresses. Pair eGFR with biomarkers + albuminuria to move from staging → risk prediction. #CKD #eGFR #KidneyHealth #PrecisionMedicine #Biomarkers
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PICKED Project @projectpicked.bsky.social · 20/02/2026
🧪 Albuminuria = albumin in urine → a leaky filtration barrier. Not just “kidney damage”: it predicts CKD progression and cardiovascular risk. #CKD #Albuminuria #KidneyHealth #PrecisionMedicine #Biomarkers #RiskStratification #PICKEDproject
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PICKED Project @projectpicked.bsky.social · 17/02/2026
📊 What is risk stratification? It’s not about how sick a patient is today, it’s about how likely they are to worsen. In CKD, this helps identify high-risk patients earlier and guide personalised care. Reactive → Predictive. #CKD #PrecisionMedicine #PICKEDproject
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