Deep-learning methods for antibody structure prediction, antibody-antigen interaction modelling and design are advancing rapidly. However, comparisons across studies remain difficult because training ...

Nature Methods - A collection of antigen-stabilizable fluorescent nanobodies becomes fluorescent upon binding to their intracellular targets and enables background-free multicolor imaging and...

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Senior Research Scientist Javier Martínez from the Instituto Investigación Sanitaria Fundación Jiménez Díaz explains his team's

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Research Scientist Rodrigo Barderas from the Instituto de Salud Carlos III describes how his team is bridging the gap between

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Research Scientist PI Alar Ainla from the International Iberian Nanotechnology Laboratory describes the role of microfluidics

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Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. Here, professor Dina Schneidman from the Hebrew University of Jerusalem explains how ALADDIN can accelerate nanobody discovery and how her te

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, our project coordinator Luis Ángel Fernández from the Centro Nacional de Biotecnología (CNB-CSIC) in Madrid, Spain, explains h

Adaptive immune receptors (AIRs), including antibodies and T-cell receptors (TCRs), mediate antigen recognition and represent a major class of therape…

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Senior Research Scientist Javier Martínez from the Instituto Investigación Sanitaria Fundación Jiménez Díaz explains his team's

Once considered tools to aid structural studies, single-domain antibodies (nanobodies) have emerged as a new class of G protein-coupled receptor (GPCR…

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Research Scientist Rodrigo Barderas from the Instituto de Salud Carlos III describes how his team is bridging the gap between

ScienceDirect is the world's leading source for scientific, technical, and medical research. Explore journals, books and articles.

Meet the ALADDIN consortium through video interviews! In this video series, our partners share key insights from the ALADDIN project and highlights of their ...

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Senior Research Scientist Javier Martínez from the Instituto Investigación Sanitaria Fundación Jiménez Díaz explains his team's

Meet the ALADDIN consortium through video interviews! In this video series, our partners share key insights from the ALADDIN project and highlights of their ...

Nature Chemical Biology - Cell-permeable nanobodies overcome a major barrier to intracellular protein targeting. Franz, Rubil and colleagues show that delivery of a CFTR-binding nanobody into...

Signal Transduction and Targeted Therapy - A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections

Meet the ALADDIN consortium through video interviews! In this series, our partners share key insights from the ALADDIN project and highlights of their work. In this video, Research Scientist Rodrigo Barderas from the Instituto de Salud Carlos III describes how his team is bridging the gap between

Nature Communications - Insect venom can cause severe allergic reactions including anaphylaxis. Here, the authors report structural and functional evidence that nanobody-based inhibitors can limit...

Meet the ALADDIN consortium through video interviews! In this video series, our partners share key insights from the ALADDIN project and highlights of their ...

ALADDIN (Accelerated Discovery Nanobody Platform) is a research project funded by the European Innovation Council (EIC)'s Pathfinder Open programme. The goal of the project is to develop and bring to the market a platform that improves the generation and identification of therapeutic nanobodies and

Bimodal imaging tracers that combine nuclear and optical modalities are gaining increasing relevance for in vivo applications in oncology, particularly for surgical guidance, where both real-time visu...