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Wei Sun

@programmingsun.bsky.social
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Reposted by Wei Sun
Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 03/04/2025
📄 ICYMI: The MorPhiC consortium’s methods were featured in Nature this February (@nature.com). The Marker Paper lays out the strategy to systematically decode gene function using perturbation and phenotyping. 🔗 www.nature.com/articles/s41... #NaturePaper #MorPhiC #CRISPR #iPSC
nature.com
MorPhiC Consortium: towards functional characterization of all human genes - Nature
This Perspective discusses strategies and challenges for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium as it aims to catalogue the molecular and cellular phenotypes associated...
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Reposted by Wei Sun
Fred Hutch Biostatistics Program @fredhutchbiostat.bsky.social · 03/04/2025
🚨 MorPhiC’s first data release is live! 🧬 71 gene/protein perturbations in the first release 🧫 iPSC-derived cells (4 genetic backgrounds) 🛠️ CRISPR, CRISPRi, degrons 📊 Bulk + single-cell RNA-seq Explore open-access data + protocols: 🔗 morphic.bio/data #MorPhiC #Genomics #OpenScience #NHGRI
morphic.bio
MorPhiC program: Molecular Phenotypes of Null Alleles in Cells
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