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Priyanka Narayan

@prinarayan.bsky.social

582 followers 144 following 5 posts

Studying cellular mechanisms of risk and resilience in neurodegenerative diseases. Views are my own.

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Reposted by Priyanka Narayan

Rik van der Kant @rikvanderkant.bsky.social · 22/09/2025

Proud to present our new paper in @natmetabolism.nature.com The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases lnkd.in/eVzFrmUY Check out our open-access platform chock-full with iPSC- and 🧠 lipidomics data (www.neurolipidatlas.com).

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Priyanka Narayan @prinarayan.bsky.social · 04/09/2025

🧪New preprint🔬🧫 Not all lipid droplets are created equal! 💥 APOE shapes the LD proteome & lipidome in astrocytes; it’s the dynamics that distinguish E2 protection from E4 risk. Led by Carla Cuni-Lopez w/ CARD proteomics, Giera lab & @rikvanderkant.bsky.social 📄 www.biorxiv.org/content/10.1...

biorxiv.org

APOE genotypes differentially remodel the astrocytic lipid droplet-associated proteome to shape lipid droplet dynamics

The lipids and proteins that comprise lipid droplets regulate several cellular functions including lipid storage, stress responses, and inflammation. Glial lipid droplets have been implicated in the p...

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Priyanka Narayan @prinarayan.bsky.social · 11/07/2025

‼️ New paper from the lab! ‼️ We uncovered links between triglyceride metabolism, microglial activation, and our favorite—APOE! 🧬🔥🧫🔬 Led by the amazing Dr. Roxan Stephenson, with a fantastic team of collaborators. Super proud of this one! Check it out 👇🏽 www.cell.com/cell-reports... Yay team! 🙌🏽

A graphical abstract showing how triglyceride metabolism is necessary for microglial activation and can be used to modulate inflammation and disease phenotypes in APOE4 microglia.

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Reposted by Priyanka Narayan

Rik van der Kant @rikvanderkant.bsky.social · 16/11/2024

For my first post, an invitation to join us in Miami! A lot of thing on ApoE and lipids are moving fast, catch up! Abstract submission is now open!

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