Reposted by Prakash
In our latest work in @chemcomm.rsc.org, we have looked into CuAAC click efficiency in complex biological medium by encapsulating them in Single-chain polymeric nanoparticles. Check it out here pubs.rsc.org/en/content/a...
Congratulations to @prakashamap.bsky.social and team.
#catalysis #chem
pubs.rsc.org
Enhancing the CuAAC efficiency of a Cu(I)-NHC complex in biological media by encapsulation
A novel [(NHC)2Cu]Br (Cu(I)-NHC) complex promotes CuAAC reactions in organic solvents, water, buffers and even in complex biological media in good yields. Encapsulation of the Cu catalyst in an amphip...