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Paolo E Porporato

@porpolab.bsky.social

259 followers 196 following 1 posts

I am Associate Professor in Experimental Biology at the University of Turin. My laboratory is interested in #cancer #metabolism and #cachexia. www.dbmss.unito.it/do/home.pl/View?…

Posts Replies Media

Paolo E Porporato @porpolab.bsky.social · 07/01/2025

Let's Start this 2025 (and this new Social) with a Post :) Our review on inter-organ crosstalk driving Cancer Cachexia is now available @cp-trendsendomet.bsky.social Systemic metabolic crosstalk as a driver of cancer cachexia by Wyart et al. #Research #CancerCachexia #Metabolism #Muscle

authors.elsevier.com

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Reposted by Paolo E Porporato

Ivan Zanoni @lozanzi.bsky.social · 05/01/2025

#WeekendRead! #MetabolismPower! @fendtlab.bsky.social &co show @ Nature that pulmonary aspartate favors lung metastases via CREB & DOHH dependent hypusination of the alternative translation factor eIF5A, driving TGFb & collagen deposition! www.nature.com/articles/s41...

nature.com

Aspartate signalling drives lung metastasis via alternative translation - Nature

Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis.

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