Pletzer lab @pletzerlab.bsky.social · 10/04/2025Lipo-peptoid TM18 disrupts P. aeruginosa and S. aureus biofilms, both individually and in co-infection. It also alleviates dermonecrosis in a murine infection model and, combined with meropenem, nearly eradicates co-infections. #AMR #biofilms #peptides www.sciencedirect.com/science/arti...sciencedirect.comA biofilm-targeting lipo-peptoid to treat Pseudomonas aeruginosa and Staphylococcus aureus co-infectionsAntibiotic-resistant bacterial infections are a significant clinical challenge, especially when involving multiple species. Antimicrobial peptides and… 010
Pletzer lab @pletzerlab.bsky.social · 08/01/2025Our latest study shows that the anti-biofilm peptide DJK-5 makes Staphylococcus aureus vulnerable to colistin in co-biofilms with Pseudomonas aeruginosa. A promising step in the fight against chronic co-infections! #AMR #Biofilms www.nature.com/articles/s41...nature.comDJK-5, an anti-biofilm peptide, increases Staphylococcus aureus sensitivity to colistin killing in co-biofilms with Pseudomonas aeruginosa - npj Biofilms and Microbiomesnpj Biofilms and Microbiomes - DJK-5, an anti-biofilm peptide, increases Staphylococcus aureus sensitivity to colistin killing in co-biofilms with Pseudomonas aeruginosa 040