Lipo-peptoid TM18 disrupts P. aeruginosa and S. aureus biofilms, both individually and in co-infection. It also alleviates dermonecrosis in a murine infection model and, combined with meropenem, nearly eradicates co-infections. #AMR #biofilms #peptides
www.sciencedirect.com/science/arti...
sciencedirect.com
A biofilm-targeting lipo-peptoid to treat Pseudomonas aeruginosa and Staphylococcus aureus co-infections
Antibiotic-resistant bacterial infections are a significant clinical challenge, especially when involving multiple species. Antimicrobial peptides and…
