We start the Year of the Horse with our new paper by Brooke Kwan, Truc Kim, @frankelab.bsky.social et al. on evodiamine diversification in Communications Chemistry.
Happy lunar new year! And happy reading!
www.nature.com/articles/s42...
nature.com
Orthologue inference-based enzyme mining for diversification of the anti-cancer evodiamine scaffold - Communications Chemistry
Cytochrome P450 monooxygenases can functionalize alkaloid scaffolds with striking stereo- and regioselectivity. Here, the authors integrate bioinformatics and enzyme discovery to identify P450 monooxy...