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Paul J Planet

@pjplanet.bsky.social
162 followers 176 following 4 posts

Pediatric Infectious Disease Doctor, Evolutionary Microbiologist

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Paul J Planet @pjplanet.bsky.social · 19/03/2025
Proud to be part of this group! journals.asm.org/doi/10.1128/...
journals.asm.org
Geographic divergence of methicillin-resistant Staphylococcus aureus ST5-SCCmecI in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genes | mBio
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of life-threatening infections worldwide and a growing public health concern. The rise of antibiotic-resistant bacteria, such as MRSA, is often linked to genetic adaptations that enhance ...
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Paul J Planet @pjplanet.bsky.social · 10/03/2025
Here is our latest on finding recombination in microbial genomes. No alignment, no phylogeny. Just information theory. Congrats Apurva and the whole team! This one was a pongvtime coming. academic.oup.com/mbe/article/...
academic.oup.com
What Do We Gain When Tolerating Loss? The Information Bottleneck Wrings Out Recombination
Abstract. Most microbes have the capacity to acquire genetic material from their environment. Recombination of foreign DNA yields genomes that are, at leas
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Reposted by Paul J Planet
Joe Zackular @joeyzacks.bsky.social · 01/03/2025
This study was made possible through an amazing collaboration across the CHOP NICU, CHOP Infectious Disease Diagnostics Lab (IDDL), CHOP Infection Prevention and Control, the Microbial Archive and Cryocollection at CHOP (MicrobialARC), and @centermicrobialmed.bsky.social.
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Reposted by Paul J Planet
Joe Zackular @joeyzacks.bsky.social · 01/03/2025
In this study we tracked carriage, transmission, and invasive infection with S. aureus across 33 months in the NICU. Using longitudinal WGS, we identify risk factors for transmission of invasive clones, and show strains that are transmitted more rapidly are more likely to cause invasive disease
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Reposted by Paul J Planet
Joe Zackular @joeyzacks.bsky.social · 01/03/2025
Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!! This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
medrxiv.org
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit (N...
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Paul J Planet @pjplanet.bsky.social · 28/02/2025
Our preprint on genomic epidemiology in the NICU! Strains that transmit faster also cause more invasive disease! nam10.safelinks.protection.outlook.com?url=https%3A...
nam10.safelinks.protection.outlook.com
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background : Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit ...
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