Reposted by @piusgalli.bsky.socialThomä lab @labthoma.bsky.social · 13/08/2026Congrats to Pius, Shuhao, and the team! Check out our latest publication: Molecular glue degraders (MGDs) like lenalidomide have transformed multiple myeloma treatment by inducing degradation of non-native substrates via the CRL4CRBN E3 ligase—but which proteins can they actually reach? 175
Reposted by @piusgalli.bsky.socialThomä lab @labthoma.bsky.social · 13/08/2026tinyurl.com/24dz4yfe #TargetedProteinDegradation, #MolecularGlue, #DrugDiscovery, #EPFL @epfllibrary.bsky.socialtinyurl.comProteome-wide identification of the druggable CRBN interactome - Nature BiotechnologyThe latent interactions of molecular glue degraders are identified proteome-wide. 142