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piusgalli.bsky.social

@piusgalli.bsky.social
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Reposted by @piusgalli.bsky.social
Thomä lab @labthoma.bsky.social · 13/08/2026
Congrats to Pius, Shuhao, and the team! Check out our latest publication: Molecular glue degraders (MGDs) like lenalidomide have transformed multiple myeloma treatment by inducing degradation of non-native substrates via the CRL4CRBN E3 ligase—but which proteins can they actually reach?
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Reposted by @piusgalli.bsky.social
Thomä lab @labthoma.bsky.social · 13/08/2026
tinyurl.com/24dz4yfe #TargetedProteinDegradation, #MolecularGlue, #DrugDiscovery, #EPFL @epfllibrary.bsky.social
tinyurl.com
Proteome-wide identification of the druggable CRBN interactome - Nature Biotechnology
The latent interactions of molecular glue degraders are identified proteome-wide.
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