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Tim Pickles

@picklestim.bsky.social
175 followers 391 following 14 posts

Research Fellow in Statistics and Deputy Director of Statistics | Centre for Trials Research, Cardiff University | Patient Reported Outcome Measures | Psychometrics | Rasch measurement theory | Rheumatoid Arthritis Disease Activity

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Reposted by Tim Pickles
Mwidimi Ndosi @ndosie.bsky.social · 17/09/2026
“How active was your arthritis in the last 6 months?” vs “How is your general health today?” General health captures broader elements like mental wellbeing and comorbidities, rather than inflammatory disease activity @picklestim.bsky.social @rheumjnl.bsky.social 🔗 doi.org/10.1093/rheu...
doi.org
Patient global assessment in rheumatoid arthritis: general health and disease activity are not interchangeable
Dear Editor, There are numerous composite response criteria and clinical outcome measures for RA disease activity (DA). Most, though not all, contain the c
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Tim Pickles @picklestim.bsky.social · 19/09/2025
So no immediate avenue to continue working towards a better future for people living with Rheumatoid Arthritis. Disappointing of course but this is the game we play in academia, and I will just have to try again on a different path. This is too important to give up on!
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Tim Pickles @picklestim.bsky.social · 19/09/2025
A huge amount of time and energy from so many people, with a range of emotions throughout, was the story behind my submission to the MRC Career Development Award. That was April. Now September brings news of rejection and no interview.
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Tim Pickles @picklestim.bsky.social · 19/09/2025
... they were comfortable sharing gave me the the clearest justification as to why this research has to continue. This all follows on from the previous post: bsky.app/profile/pick...
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Tim Pickles @picklestim.bsky.social · 19/09/2025
I also found my first experience of using qualitative research methods (having spent 13.5 years employed as a statistician to the point of starting the interviews) was thoroughly enjoyable and entirely eye-opening. Whilst taking to the interviewees about a very niche topic, the stories ...
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Tim Pickles @picklestim.bsky.social · 19/09/2025
I found: - There were no items or concepts missing that should be covered. - There was some initial evidence of content validity for these items. - General health and fatigue are separate to the construct of RA disease activity.
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Tim Pickles @picklestim.bsky.social · 19/09/2025
And here comes a 3rd article from my @researchwales.bsky.social funded PhD/fellowship hosted by @ctrcardiffuni.bsky.social: this on the content validity of a 12-item item pool to measure the construct of Rheumatoid Arthritis Disease Activity doi.org/10.1093/rheu...
doi.org
Assessing the content validity of a Patient Reported Outcome Measure item pool for Rheumatoid Arthritis Disease Activity using cognitive interviews
AbstractObjectives. Using Rasch measurement theory, an item pool of 12 questions has been identified, covering tenderness and swelling, disease activity, p
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Reposted by Tim Pickles
Rhiannon Phillips @nannon-phillips.bsky.social · 11/08/2025
Latest paper out now from @picklestim.bsky.social's doctoral work - congratulations Tim! Shows good content validity for a brief set of 12 items that were identified using Rasch measurement theory for assessing rheumatoid arthritis disease activity. academic.oup.com/rheumatology...
academic.oup.com
Assessing the content validity of patient reported outcome measure item pool for rheumatoid arthritis disease activity using cognitive interviews
AbstractObjectives. Using Rasch measurement theory, an item pool of 12 questions has been identified, covering tenderness and swelling, disease activity, p
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Reposted by Tim Pickles
Centre for Trials Research @ctrcardiffuni.bsky.social · 07/08/2025
@picklestim.bsky.social reflects on his journey through a Doctoral Fellowship and Next Steps Award—and how it's shaped his research career. 🔗 youtu.be/eYV3HUcZehc @researchwales.bsky.social @ukcrc-ctu.org.uk 📊🧠
youtu.be
Reflections on my Doctoral Fellowship and Next Steps Award journey with Dr Tim Pickles
YouTube video by #ResearchWalesFaculty TV
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Tim Pickles @picklestim.bsky.social · 30/07/2025
This is just the start. There is more refinement to come and more research I need to do.
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Reposted by Tim Pickles
The BMJ @bmj.com · 28/07/2025
Skin cancer is the most commonly diagnosed cancer worldwide. What is the current evidence for skin cancer prevention and how to best use sunscreens? Read the full guidance or check out this visual summary #BMJInfographic www.bmj.com/content/390/...
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Tim Pickles @picklestim.bsky.social · 17/07/2025
Fantastic way to sign off my PhD @cardiffuni.bsky.social in the @ctrcardiffuni.bsky.social, and lovely to graduate with my friend and colleague Mandy Lau #CardiffGrad
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Tim Pickles @picklestim.bsky.social · 08/07/2025
Front cover of European Burn Journal for CARe Burn Scales! Congratulations Catrin Griffiths Ella Guest @dianaharcourt.bsky.social 🥳 @ctrcardiffuni.bsky.social www.mdpi.com/2673-1991/6/2 doi.org/10.3390/ebj6...
Front cover of European Burn Journal, Volume 6, Issue 2, June 2025, showing a hand on skin that is recovering after a burn
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Tim Pickles @picklestim.bsky.social · 08/07/2025
Great to have this published in @painreports.bsky.social doi.org/10.1097/PR9.... Congratulation Stephanie Smith and team. I was happy to provide further CAP-RA data for analyses as part of the SOCRATES data collection funded by @researchwales.bsky.social @ctrcardiffuni.bsky.social
doi.org
Validity and contributions to pain from the central aspects ... : PAIN Reports
is. Objectives: Given the different pathophysiology of rheumatoid arthritis (RA), an inflammatory polyarthritis, this cross-sectional study assessed CAP's psychometric properties and its associatio...
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Reposted by Tim Pickles
Centre for Trials Research @ctrcardiffuni.bsky.social · 03/07/2025
📝 Discover how funding shapes research careers! Dr Tim Pickles reflects on his Health and Care Research Wales awards + next steps at a free webinar on Tues 15 July 2025. 🎯👨‍🏫 🔗 healthandcareresearchwales.org/about/events... @researchwales.bsky.social @cardiffuni.bsky.social @ukcrc-ctu.org.uk
healthandcareresearchwales.org
Faculty webinar: Reflections on my Doctoral Fellowship and Next Steps Award journey with Dr Tim Pickles
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Tim Pickles @picklestim.bsky.social · 09/06/2025
Thank you to my excellent supervisors, clinical colleagues and PPI contributors Mike Horton, Karl Bang Christensen, Rhiannon Phillips, David Gillespie, Neil Mo, Janice Davies, Susan Campbell and Ernest Choy. And thank you to my colleagues at @ctrcardiffuni.bsky.social
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Tim Pickles @picklestim.bsky.social · 09/06/2025
- Adding to the result from my systematic review doi.org/10.1136/rmdo... no legacy RA DA PROMs have evidence of good measurement properties.
doi.org
Patient Reported Outcome Measures for Rheumatoid Arthritis Disease Activity: a systematic review following COSMIN guidelines
Background The current standard of care in rheumatoid arthritis (RA) requires regular assessment of disease activity (DA). All standard RA DA measurement instruments require joint counts to be underta...
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Tim Pickles @picklestim.bsky.social · 09/06/2025
I found: - the construct of RA Disease Activity can be measured using items from the Pain, Tenderness and swelling, Physical functioning, Disease Activity and Stiffness domains; - General health and Disease activity items are not interchangeable within the Patient Global Assessment domain;
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Tim Pickles @picklestim.bsky.social · 09/06/2025
Excited to share the second published article from my PhD funded by @researchwales.bsky.social on Patient Reported Outcome Measures for Rheumatoid Arthritis Disease Activity. doi.org/10.1093/rheu...
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