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Valvular heart disease (VHD) is a common condition that poses several challenges from the standpoints of diagnosis and therapeutic management. While several studies have explored the role of blood bio...

Cath Lab Attire: ‘Dress Up and Shut Up’ or Time for a Change? sciprian@crf.org Thu, 03/27/2025 - 12:36 Bouffant caps, beard covers, and more—the idea is to prevent infection. Some say the requirements are overkill.

Nature Reviews Cardiology, Published online: 28 March 2025; doi:10.1038/s41569-025-01147-wCountries globally face major challenges in the early diagnosis and treatment of hypercholesterolaemia and cardiovascular disease, with numerous health inequities by geography and income. Perseverance, hard work, integrity and commitment can transform aspiration into reality. My PCSK9 story, from the discovery of its implication in familial hypercholesterolemia to the development of life-saving drugs, is a real example.

Extreme hypertriglyceridemia, defined as triglyceride (TG) levels ≥1000 mg/dL, is almost always indicative of chylomicronemia. The current diagnostic …

Fasting Not Needed Before Cath Lab Procedures: Meta-analysis sciprian@crf.org Tue, 03/11/2025 - 09:35 Todd Neale It’s “time to get rid of this age-old practice,” said Sripal Bangalore, who noted that patients are happier when not fasting.

REVIVED/STICHES Analysis Questions Surgery’s Benefit in Ischemic HF sciprian@crf.org Tue, 03/11/2025 - 11:56 Michael O'Riordan There are hints that the 10-year benefit seen in STICHES, the earlier trial, might be the result of inferior medical…

Years After Radiation Therapy, Echo Parameters Worse in Breast Cancer Patients sciprian@crf.org Tue, 03/11/2025 - 13:47 Caitlin E. Cox Even modern cancer treatments appear risky for the heart, especially if the radiation dose to the LAD is high.

This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.

Nature Reviews Cardiology - The brain–heart axis comprises the anatomical and functional interaction between the neural and cardiovascular systems that regulate physiological, cognitive and...

Danish Analysis Updates Stroke and MI Risks of Contemporary Contraceptives hdellabella@crf.org Mon, 03/03/2025 - 15:41 L.A. McKeown Though arterial thrombotic risk was higher with hormonal contraception use, the absolute excess risks were low.

Join the HFpEF Summit, March 19–21, 2025, at The Maybourne Beverly Hills. Connect with global leaders in HFpEF research.

Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis-The Time Has Come

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In REGARDS participants without diabetes, HbA1c values from frozen whole blood and packed cell samples under long-term storage correlated in the expected manner with fasting glucose values and severa...