Thermopiles transformed our understanding of muscle thermodynamics. Read about AV Hill and how he refined the instrument.

Glucagon plays a pivotal role in hepatic amino acid metabolism; acute high-protein diet feeding and diabetic condition both induce enhanced glucagon secretion. However, it remains unknown whether…

Phosphodiesterase-5 inhibitors have beneficial pleiotropic effects and hold promise as adjuvant treatments for cancer, dementia, and other disorders. Sixteen men and women aged 50–60 were…

Created in BioRender. Megowan, H. (2026) https://BioRender.com/9457v5e.

Loss of glyoxalase 1 has a minimal impact on protein glycation in a murine model for metabolic syndrome. These mice have reduced hepatic steatosis despite impaired glucose handling.

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Cities are getting brighter at night with well-lit crosswalks, sidewalks and paths through parks and wooded areas. Lighting can make it easier for drivers, bicyclists and runners to navigate the darkness safely. But increased lighting has unintended consequences for wildlife, including songbirds. Just like humans, songbirds are active during the day and sleep at night. … Continue reading Maybe Birds Need Sleep Masks Too

Peer Review Week (PRW) is a global celebration of the vital role peer review plays in ensuring the quality and integrity of research.

Peer Review Week (PRW) is a global celebration of the vital role peer review plays in ensuring the quality and integrity of research.

1-4 July, Stockholm, Sweden

Vascular expansive remodeling is involved in atherosclerosis/restenosis; however, its mechanisms need further investigation. Protein-disulfide isomerase (PDIA1), a redox chaperone from the…

Acute muscle strain injuries belong to the most frequent sports injuries with high recurrence rates. Biopsies obtained from previously strain-injured muscles showed fat intra- and intermuscular, but…

Most of us know that regular physical activity is great for health, reducing risks of heart disease and even lowering the risk of death. Walking is one of the easiest ways to fit in physical activity, and even just a little more walking can make a difference. For example, taking an additional 1,000 steps each … Continue reading How Many Steps a Day for Better Health? It Might Be Fewer Than You Think

Enhanced measurement of Kidney Functional Reserve (KFR) by biomarkers: Protein ingestion stimulates intrarenal blood flow and increases glomerular filtration rate (GFR). KFR is [stimulated –…

Hypoglossal and lumbar motor neurons (MNs) surival is essential for maintiaining neuromotor health into old age. We observed loss of predominantly larger hypoglossal and lumbar MNs in 24 compared to…

Presynaptic vesicle pools, particularly the readily releasable pool (RRP), are essential for synaptic transmission. The RRP comprises fast-release pool (FRP) and slow-release pool (SRP)…

The Physiological Society's Rob Clarke Awards recognise excellence in undergraduate physiology projects. Submit your abstract and present.

Amino acids are fundamental to life as protein building blocks and key regulators of metabolism and signaling. The kidney plays a critical, yet underappreciated, role in amino acid homeostasis…