iiinova — where your digital self keeps evolving

Dr. Patrick Hwu @patrickhwumd.bsky.social · 10/09/2025

It was a pleasure to share the latest on next-gen cell therapies @ufhealthcancer.bsky.social today. Thank you for the opportunity to kick off your fall Grand Rounds. It’s always inspiring to connect with colleagues who share our drive to push the boundaries of discovery and care.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 11/08/2025

Had fun trying some new songs with @drdanarocks.bsky.social! What do you think of our take on the Chapell Roan megahit #PinkPonyClub? #MusicMonday #DocsWhoRock #TheReMissions

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 24/05/2025

#ScienceSaturday 🧵 ❓ How can we target pancreatic cancer with T cells?

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 03/05/2025

#ScienceSaturday 🧵 ❓ How does aging affect the immune cells infiltrating tumors? ➡️ As we age, our circulating blood and immune cells can develop mutations called clonal hematopoiesis of indeterminate potential (CHIP).

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 15/04/2025

🗣️ Share this with the women in your life! The @NCCN has shared updated screening guidelines for women with extremely dense breasts. Moffitt’s Dr. Bethany Niell explains the new guidelines and why they are important. www.moffitt.org/endeavor/arc...

moffitt.org

Screening Guidelines Updated for Women With ‘Extremely Dense’ Breasts

Recommendations now encourage supplemental breast MRIs for certain patients

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 11/04/2025

Excited to be joined by biotech executives, entrepreneurs, investors and researchers today at #MoffittBoB to discuss the latest advances in cancer care. A big thank you to Florida Secretary of Commerce Alex Kelly for kicking off the event at our leadership breakfast. @moffittnews.bsky.social

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 01/04/2025

📢 New landmark research out today on #TILTherapy for GI cancers ❓Can neoantigen-specific tumor-infiltrating lymphocytes (TILs) improve #immunotherapy for gastrointestinal cancers?

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 31/03/2025

Happy #NationalDoctorsDay! Join me in recognizing all of our inspiring docs who make a difference in the lives of our patients every day @moffittnews.bsky.social! Photos from our Doctors’ Day lunch celebration! 🩺🥼

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 29/03/2025

#ScienceSaturday 🧵 ➡️ Melanoma secretes a protein called midkine (MDK), which plays a key role in reprogramming dendritic cells in the tumor microenvironment. ❓ How can this impact immune responses?

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 26/03/2025

Thank you to Lakeland Commissioner Stephanie Madden and other Polk County leaders for joining us this week to tour our brand-new Moffitt at SouthShore ambulatory center!

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Reposted by Dr. Patrick Hwu

Moffitt Cancer Center @moffittnews.bsky.social · 07/03/2025

Moffitt Cancer Center is proud to be the first standalone cancer center in the world to open a Nikon Center of Excellence! This prestigious achievement reflects our commitment to cutting-edge imaging technology and groundbreaking cancer research. Read more: bit.ly/41L1R0L

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 01/03/2025

#ScienceSaturday 🧵 ❓ Are B cells important to eliminate cancers? T cells, capable of directly killing cancers, have been widely studied in tumor immunology.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 14/02/2025

Moffitt’s #PetTherapy dogs, Kayba, CJ and Kayse are ready for a pawesome #Valentinesday2025! ❤️ 🐾 Thanks to @moffittnews.bsky.social volunteer Ken Price for bringing them to spread cheer among our patients and teams at Moffitt McKinley Outpatient Center!

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 13/02/2025

Gratitude isn’t just important for the present, but the past and future, too. #ThursdayThoughts

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 08/02/2025

#ScienceSaturday 🧵 🧬 Personalized cancer vaccines (PCV) train the immune system to recognize mutations unique to a patient's tumor, helping the body mount a targeted immune response. ❓ Can this approach help prevent renal cell carcinoma (RCC) from returning after surgery?

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Moffitt Cancer Center @moffittnews.bsky.social · 07/02/2025

Join us in congratulating H. Lee Moffitt, the Outstanding Citizen of the Year, for his dedication to Tampa Bay and beyond! His vision led to a world-class cancer center, ensuring patients could receive top care in Florida. Read more: bit.ly/4aTbP4i #MoffittCancerCenter

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Reposted by Dr. Patrick Hwu

Moffitt Cancer Center @moffittnews.bsky.social · 31/01/2025

Moffitt will be among a select group of elite U.S. cancer centers — and the only one in Tampa Bay — equipped with a next-generation, FDA-cleared, state-of-the-art proton therapy system. www.moffitt.org/newsroom/new...

moffitt.org

Moffitt Cancer Center Is First Health System in Tampa Bay Area To Receive Proton Therapy System for Cancer Treatment

IBA’s Proteus®ONE, arriving in February, will be the most advanced in the Tampa Bay area

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Moffitt Cancer Center @moffittnews.bsky.social · 03/02/2025

On National Women Physicians Day, we celebrate the women at Moffitt who are transforming cancer care through advocacy, research and compassionate patient-centered care. Read more about their impact: bit.ly/413kBte #NWPD @jessicayislam.bsky.social

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 01/02/2025

#ScienceSaturday 🧵 ➡️ Immunotherapies targeting neoantigens can be effective in mediating long-term durable responses in advanced cancer patients. However, identifying these neoantigens from metastatic tumors can be logistically challenging.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 30/01/2025

As leaders, we can shape the future of cancer care and research by mentoring the next generation! Lift others as you climb! #ThursdayThoughts

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 28/01/2025

I am thrilled that @moffittnews.bsky.social has been named a Best and Brightest Company to Work For in the Nation once again! This honor reflects our incredible team and culture of excellence as we work together to contribute to the prevention and cure of cancer. www.moffitt.org/newsroom/new...

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 28/01/2025

Happy #MusicMonday! #TheReMissions had so much fun covering “All of Me” by the legendary Billie Holiday. Music has a way of bringing us together and lifting spirits. Hope this brightens your day! @drdanarocks.bsky.social #DocsWhoRock

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 27/01/2025

Do you know what a biorepository is? 🧊❄️ @moffittnews.bsky.social, we're bringing deep-freeze technology to the Sunshine State to advance cancer research and care. Read more to see how this cutting-edge facility will help save lives: www.moffitt.org/endeavor/arc...

moffitt.org

Moffitt Bringing Deep Freeze Temps to the Sunshine State

The new 30,000-square-foot CRYOGENE facility will house Moffitt’s biospecimen collection and offer services to future partners

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 25/01/2025

#ScienceSaturday 🧵 ❓ What is the "obesity paradox" in cancer #immunotherapy? ➡️ Although obesity increases the risk of #cancer, it's also been linked with better outcomes for some patients treated with immune checkpoint inhibitors (ICIs), a type of immunotherapy.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 23/01/2025

We are so thrilled to begin serving patients at Moffitt at SouthShore in just a few short days. Learn more about the newest @moffittnews.bsky.social facility in this piece from ABC Action News! www.abcactionnews.com/news/region-...

abcactionnews.com

Moffitt Cancer Center opens new facility in Ruskin

On Friday, more than 200 team members had the opportunity to tour the new 75,000-square-foot Moffitt Cancer Center at SouthShore in Ruskin.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 21/01/2025

So great to connect with fellows from our Urologic Oncology, BMT, Gynecologic Oncology and Pathology teams @moffittnews.bsky.social at a recent breakfast with Dr. Karen Lu and Dr. John Cleveland! Thank you for your important role in shaping the future of oncology!

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Reposted by Dr. Patrick Hwu

Moffitt Cancer Center @moffittnews.bsky.social · 21/01/2025

Enjoyed having the Stanley Cup visit Moffitt Cancer Center today! 🏆

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Reposted by Dr. Patrick Hwu

Dr. Dana @drdanarocks.bsky.social · 21/01/2025

Acts of injustice—from discrimination to genocide—are only made possible when we allow dehumanization & hate into our hearts and communities. We All is a song about love & seeing ourselves in the “other”. Hate cannot drive out hate. Only love can do that. #MLK #MusicMonday

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 19/01/2025

#ScienceSaturday 🧵 ➡️ T cells recognize tumors through binding of their T-cell receptors (TCRs) to peptide antigens within MHC molecules. ❓ What is the optimal strength of this receptor binding, known as “avidity”, to mediate antitumor immunity?

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Moffitt Cancer Center @moffittnews.bsky.social · 16/01/2025

While at the 43rd Annual J.P. Morgan Healthcare Conference, Moffitt and @Cryoportinc leaders celebrated a major milestone. Cryoport’s CRYOGENE will provide Moffitt's #SperosFL with state-of-the-art biorepository services. Read more about this strategic partnership: bit.ly/40yKMaG #JPM25 #JPMHC25

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 17/01/2025

Running a cancer center requires a massive team effort, where every decision, discovery and patient interaction contributes to the big picture. #ThursdayThoughts

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Reposted by Dr. Patrick Hwu

Moffitt Cancer Center @moffittnews.bsky.social · 15/01/2025

Diagnosed with stage 4 metastatic breast cancer just a week after giving birth, Dallas Carroll faced an uncertain future. But an experimental vaccine gives her a shot at a cure. Discover how cutting-edge treatments like dendritic cell vaccines are transforming lives. #CancerResearch

buff.ly

Experimental Vaccine Gives Young Mother a Shot at Cure

Dallas Carroll was 29 when she was diagnosed with stage 4 metastatic breast cancer. She had just given birth to her son, Dakota.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 15/01/2025

Honored to speak today at the Hillsborough County Board of County Commissioners meeting, where we had a great conversation about advancing #cancer care across Tampa Bay and beyond. Excited to highlight the opening of our newest outpatient center, Moffitt at SouthShore! @moffittnews.bsky.social

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 15/01/2025

Enjoyed listening to special guest Dr. Tullia Bruno speak on the role of B cells in tumor immunity today @moffittnews.bsky.social. Great talk! Thank you for joining us for our #Immunology seminar series.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 14/01/2025

As a tribute to former president Jimmy Carter, #TheReMissions covered "Georgia on My Mind." Carter's successful treatment for metastatic #melanoma brought immunotherapy into the limelight, inspired hope for countless patients, and reminds us of the power of #CancerResearch! #MusicMonday

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 11/01/2025

(1/3) #ScienceSaturday ➡️ How does the history of T cells impact their ability to fight #cancer when engineered with chimeric antigen receptors?

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Moffitt Cancer Center @moffittnews.bsky.social · 10/01/2025

The ribbon has been cut! We are eager to welcome patients at #MoffittSouthShore beginning January 27th, 2025.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 10/01/2025

Moffitt at SouthShore Feb. 2024 ➡️ Jan. 2025. Watch our Grand Opening live on YouTube at bit.ly/3DT0t3S @moffittnews.bsky.social

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 09/01/2025

Cancer care and research is an ever-evolving field, and our work reminds us that truly impactful progress can often be made by forging new paths. #ThursdayThoughts

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Reposted by Dr. Patrick Hwu

Moffitt Cancer Center @moffittnews.bsky.social · 07/01/2025

This summer, Moffitt McKinley Hospital celebrated its first year of serving patients. Team members have embraced the Moffitt culture, offering smiles, support and care to all. Discover their impactful moments from the past year. 👇

bit.ly

Everyday Interactions, Extraordinary Impact: Moffitt McKinley Hospital Celebrates a Year of Serving Patients

A focus on outstanding care marks first year of memories at Moffitt McKinley Hospital

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 08/01/2025

About 1/3 of all cancers diagnosed annually can be prevented, and more can be cured by early detection through screening. Do you know what #cancer screenings you should get? Check out the recommended screenings and prioritize your health this New Year! www.moffitt.org/endeavor/arc...

moffitt.org

Make a New Year’s Resolution to Schedule a Cancer Screening

Is cancer prevention one of your goals for 2025?

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 07/01/2025

Nothing like recreating a classic in your own unique style. Loved doing this cover of “Somewhere Over the Rainbow” with @drdanarocks.bsky.social and #MarkRobertsonTessi! #MusicMonday #TheReMissions #DocsWhoRock

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 04/01/2025

#ScienceSaturday #CancerVaccines are being intensively studied and may one day become an important modality to treat cancer and prevent recurrence.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 03/01/2025

We are all the authors of our own story. What will you write in yours this year? #ThursdayThoughts

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 31/12/2024

Reflecting on the groundbreaking research of 2024 @moffittnews.bsky.social ! From innovative treatments to breakthrough discoveries, we continue to push boundaries in cancer care. 🔗 Read more here: www.moffitt.org/endeavor/arc... Excited for what’s to come in 2025. 🎉

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 28/12/2024

(1/3) #ScienceSaturday Treating #neurological disorders like #brain tumors is difficult in part due to a protective “wall” called the blood-brain barrier, meant to block toxins from reaching brain cells.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 21/12/2024

#ScienceSaturday HER2-positive #BreastCancer is notoriously aggressive and difficult to treat. A study led by Dr. Brian Czernicki involved injecting immune-boosting dendritic cells directly into tumors in combination with targeted therapies before chemotherapy.

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Dr. Patrick Hwu @patrickhwumd.bsky.social · 15/12/2024

#ScienceSaturday CD28 is an important costimulatory molecule for T cells. However, in a recent study, Yang et al utilized a whole genome CRISPR screen in a breast cancer model to identify that tumors can also use CD28 signaling to inhibit T cells through upregulation of PDL1 on the tumor surface.

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