Author summary Understanding which genetic variants influence complex traits and diseases is essential for gaining biological insight and developing new treatments. However, large-scale genetic studie...

Proud to share that our research group, Genomic Medicine, has contributed to a recent study investigating the potential mechanisms underlying pregnancy loss. While chromosomal abnormalities are well-...

Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet

Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet

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Background Gene set tests can pinpoint genes and biological pathways that exert small to moderate effects on complex diseases like Type 2 Diabetes (T2D). By aggregating genetic markers based on biolog...

Author summary Our study introduces a new method for prioritizing biological pathways in complex diseases using Bayesian Linear Regression (BLR) models. Genome-wide association studies (GWAS) have sig...

Provides an infrastructure for efficient processing of large-scale genetic and phenotypic data including core functions for: 1) fitting linear mixed models, 2) constructing marker-based genomic relati...