🧬 New in PLOS Genetics!
We show how Bayesian Linear Regression models can powerfully fine-map genetic variants underlying complex traits & diseases — matching state-of-the-art methods on both simulated & UK Biobank data.
📄 doi.org/10.1371/journal.pgen.1011783
#Genomics #FineMapping #UKBiobank
doi.org
Enhanced genetic fine mapping accuracy with Bayesian Linear Regression models in diverse genetic architectures
Author summary Understanding which genetic variants influence complex traits and diseases is essential for gaining biological insight and developing new treatments. However, large-scale genetic studie...