iiinova — where your digital self keeps evolving

Kevin Baker @orthoengineer.bsky.social · 18/09/2026

Gonna be a long night at HighMark. 😵‍💫 @detroitlions.bsky.social

Kevin Baker @orthoengineer.bsky.social · 18/09/2026

Irrationally nervous about the @detroitlions.bsky.social vs. @buffalo-bills.bsky.social match up tonight. Will we get the 1st half or 2nd half Lions from Sunday? 😬

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Kevin Baker @orthoengineer.bsky.social · 22/06/2026

Fantastic new article from the Gardinier Lab! Comprehensive in vitro and in vivo work to show the role of ARHGEF3 deletion in bone formation.

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Kevin Baker @orthoengineer.bsky.social · 22/06/2026

Guess I've been walking widdershins for no reason at all.

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Kevin Baker @orthoengineer.bsky.social · 12/12/2025

New pre-print up on bioRxiv! In it, we discuss the acute effects of intra-articular IDO-1 administration after ACL injury. Inflammatory cytokines ⬇️. Circulating Tregs⬆️. Joint tissue CTLA4+ cells ⬆️. And more! www.biorxiv.org/content/10.6...

biorxiv.org

Acute Effects of Intra-Articular Liposomal IDO-1 following Anterior Cruciate Ligament Injury

Joint injuries, such as rupture of the anterior cruciate ligament (ACL), is associated with the development of post-traumatic osteoarthritis (PTOA). It is known that ACL rupture can lead to disruption...

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Kevin Baker @orthoengineer.bsky.social · 27/11/2025

Awesome to see our Department Chair @shouldergeek.bsky.social and members of the @henryfordhealth.bsky.social Sports Med team at America's Thanksgiving Parade in #Detroit!

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Kevin Baker @orthoengineer.bsky.social · 10/11/2025

Who says PIs dont stand by their posters!? Presenting our ACL reconstruction research at #TERMISAM2025 in #Detroit.

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Kevin Baker @orthoengineer.bsky.social · 17/10/2025

Fantastic time at the 18th World Congress of the International Cartilage Regeneration & Joint Preservation Society in Boston. Presented our work on IDO-1 and #Kynurenines in #osteoarthritis, and a project focused on improved healing in #ACL reconstruction. As always - huge thanks to the team!

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Kevin Baker @orthoengineer.bsky.social · 20/09/2025

Another great publication from @amandality.bsky.social and team! Sure does make one reconsider the old "wear and tear" hypothesis about #osteoarthritis. Exciting times in OA research!

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Kevin Baker @orthoengineer.bsky.social · 16/08/2025

Amazing #fishing trip to Northern Ontario with K1 before he moves in @umich.edu next week! 🥹

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Kevin Baker @orthoengineer.bsky.social · 31/07/2025

More miR-awesomeness from @amandality.bsky.social and team in the @hfhs-bjc.bsky.social! Great diagnostic potential for miR's in both #Osteoarthritis and #RheumatoidArthritis.

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Kevin Baker @orthoengineer.bsky.social · 26/07/2025

Excited to put this new system to good use, and thankful for the rich history of uCT imaging here @hfhs-bjc.bsky.social from the Yeni Lab. Looking forward to some fun contrast-enhanced imaging of articular cartilage and intervertebral disc! #orthosky

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Kevin Baker @orthoengineer.bsky.social · 16/07/2025

We got some fishing in on the Huron River yesterday in Ann Arbor after K1 finished new student orientation @umich.edu.

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Kevin Baker @orthoengineer.bsky.social · 23/06/2025

This was a fantastic opportunity to strengthen ties with our @michiganstateu.bsky.social colleagues! Grateful to be able to share our stem cell mobilization work. Many thanks to the Co-Chairs @amandality.bsky.social @mattharkeyphd.bsky.social, Charles Day MD and Jane Manfredi DVM PhD!

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Kevin Baker @orthoengineer.bsky.social · 30/05/2025

Our paper on enhancing the repair of #RotatorCuff tears using pharmacologic methods to recruit endogenous MSCs is out in AJSM today! The project was fun, but I can't say enough about my amazing co-authors. Read it here: journals.sagepub.com/doi/10.1177/...

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Reposted by Kevin Baker

Henry Ford Bone & Joint Center @hfhs-bjc.bsky.social · 10/05/2025

Another fantastic @henryfordhealth.bsky.social Research Symposium in the books! Inspiring to hear about all of the awesome research from across the campus. Equally amazing to hear from @boneybonebone.bsky.social of the Yeni Lab @hfhs-bjc.bsky.social talking about facet joint measurement via DTS!

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Kevin Baker @orthoengineer.bsky.social · 27/03/2025

K1 sent pics below of the 🇳🇱 flagged Iver Bright tanker (left) and the 989 ft. M/V American Century diesel-powered freighter (right) while fishing on the St. Clair River.

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Kevin Baker @orthoengineer.bsky.social · 14/03/2025

With the @tigers.bsky.social home opener less than two weeks away, it's time to channel Sparky Anderson. #GrittyTigers #Detroit

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Kevin Baker @orthoengineer.bsky.social · 01/03/2025

Great paper from @boneybonebone.bsky.social of the Yeni Lab in the @hfhs-bjc.bsky.social. DTS could be very useful for understanding facet joint loading associated with spondyloarthropathies, or even new interbody or interspinous spacer devices! #Orthosky #Spine

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Kevin Baker @orthoengineer.bsky.social · 27/02/2025

Grateful to be a (very) small part of such an amazing study! All credit to the awesome @amandality.bsky.social and her team for this important #osteoarthritis discovery just published in @naturecomms.bsky.social. The miR-evolution is now!

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Kevin Baker @orthoengineer.bsky.social · 15/02/2025

A very Detroit end to day spent helping some neighbors. Spotted this pheasant pair just off Kercheval and Field. (Sorry for the poor quality)

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Kevin Baker @orthoengineer.bsky.social · 04/02/2025

ACL rupture frequently leads to post-traumatic osteoarthritis. We previously showed that ACL rupture disrupts conversion of Tryptophan (Trp) to Kynurenine (Kyn). Injecting IDO-1 into the knee after ACL rupture we restore Trp -> Kyn...and downstream Kyn metabolites! More on these later!

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Kevin Baker @orthoengineer.bsky.social · 25/01/2025

Our folks just sent pictures of the St. Clair River in East China, Michigan. Lots of ice piling up and the CGC Mackinaw cutting a path.

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Kevin Baker @orthoengineer.bsky.social · 18/01/2025

Was great to be back at @michigantech.bsky.social and hanging in the Keweenaw Peninsula again for a few days!

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Kevin Baker @orthoengineer.bsky.social · 28/12/2024

Took advantage of the unseasonable weather today and went fishing with the whole family on the Huron River in Ann Arbor. No fish but plenty of fresh air and sunshine!

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Kevin Baker @orthoengineer.bsky.social · 27/12/2024

Time to get the new printer up and running for the boys!

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Kevin Baker @orthoengineer.bsky.social · 25/12/2024

The 1,013.5 ft. M/V Paul R. Tregurtha was anchored just offshore in East China, Michigan on the St. Clair River today. Longest #freighter on the #GreatLakes!

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Kevin Baker @orthoengineer.bsky.social · 21/12/2024

I love the random, amazing stuff one can find walking around Detroit...like this awesome firetruck in Corktown!

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Kevin Baker @orthoengineer.bsky.social · 29/11/2024

The Tryptophan slander is egregious this Thanksgiving. Like, do you want neurotransmitters? Would you like some NAD+, or we just skipping Kynurenines altogether?

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Kevin Baker @orthoengineer.bsky.social · 28/11/2024

One of the best parts of our lab being on Woodward Ave in #Detroit is being able to walk out the evening before to see the floats lined up for the #ThanksgivingDay parade!

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Kevin Baker @orthoengineer.bsky.social · 26/11/2024

Ahead of Thanksgiving in the U.S., where people will blame the 🦃 for afternoon naps, I wanted to share some (low-res) MALDI-MSI of Tryptophan metabolites. H&E, L-Tryptophan, L-Kynurenine, and Kynurenic Acid in rat knees with non-invasive ACL injury. #orthosky #orthopedics #arthritis

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Kevin Baker @orthoengineer.bsky.social · 22/11/2024

While Michigan deer hunters are out in the fields and forests, two bucks decided the metro Detroit suburbs were much safer. (Not pictured: the doe they were both chasing, who was sooo not interested.) #Michigan

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Kevin Baker @orthoengineer.bsky.social · 20/11/2024

Hoping to connect with others in the orthopaedic research and broader STEM community. Apologies in advance for incessantly posting about @detroitlions.bsky.social football!

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