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Theobald Smith Society @njmicrobe.bsky.social · 02/09/2025

Tiny but mighty: Rutgers study shows the 34-aa protein YoaI links phosphate, Mg²⁺, and osmotic stress pathways in E. coli. Small proteins = key cross-talk mediators in bacterial stress signaling. go.njmicrobe.org/1HDIM2 #Microbiology #SmallProteins #StressSignaling #Rutgers

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Theobald Smith Society @njmicrobe.bsky.social · 11/08/2025

ASM, ASBMB, ASCB & FASEB urge SCOTUS to block NIH from withholding canceled grants, warning of lasting harm to early-career scientists & U.S. science leadership. asm.org/press-releas.... #ResearchFunding #NIH #SciencePolicy

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Theobald Smith Society @njmicrobe.bsky.social · 05/03/2025

David Alland’s group at Rutgers Medical School identified the optimal tongue swab processing method for detecting Mycobacterium tuberculosis and rifampicin resistance using Cepheid’s Xpert MTB/RIF Ultra assay, as an alternative to sputum samples. journals.asm.org/doi/10.1128/...

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Theobald Smith Society @njmicrobe.bsky.social · 04/03/2025

The Herrera Lab at the Rutgers Global Health Institute along with Senegalese colleagues investigated the seroprevalence of Chikungunya virus and O'nyong-nyong virus in Senegal, West Africa, using samples from 470 non-febrile subjects. onlinelibrary.wiley.com/doi/10.1002/...

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Theobald Smith Society @njmicrobe.bsky.social · 02/03/2025

Zoe Narvaez successfully defended her PhD thesis in the Dept. of Entomology at Rutgers University. Her research focused on tick surveillance & pathogen prevalence in New Jersey, drawing from comprehensive field studies and molecular techniques. See more at: www.njmicrobe.org/post/congrat...

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Theobald Smith Society @njmicrobe.bsky.social · 15/02/2025

Researchers at Rutgers University Department of Food Science explored the effectiveness of plasma-activated mist, generated by combining dielectric barrier discharge plasma with nebulized liquid micro-droplets, in inactivating bacteria on fresh produce. www.sciencedirect.com/science/arti...

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Theobald Smith Society @njmicrobe.bsky.social · 05/02/2025

Thomas Dick’s lab at Hackensack Meridian found adding the FDA-approved durlobactam-sulbactam combination to β-lactam antibiotics imipenem and cefoxitin can significantly improve their potency and bactericidal activity against Mycobacterium abscessus. journals.asm.org/doi/10.1128/...

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Theobald Smith Society @njmicrobe.bsky.social · 04/02/2025

Rutgers found a new antibiotic, MGC-10, inhibiting bacterial protein synthesis by targeting the EF-Tu:tRNA. It is effective against a broad range of AMR Gram+ including MRSA. Although it's too toxic for systemic use and is proposed as a potential topical treatment. journals.asm.org/doi/full/10....

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Theobald Smith Society @njmicrobe.bsky.social · 02/02/2025

Barry Kreiswirth's lab at Hackensack Meridian examined the interplay between its CRISPR-Cas systems, anti-CRISPR proteins, and AMR genes that contribute to the global success of multi-drug resistant Klebsiella pneumoniae clone CG147. genomemedicine.biomedcentral.com/articles/10....

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Theobald Smith Society @njmicrobe.bsky.social · 26/01/2025

The Shaevitz Lab and Gitai Lab at Princeton explored the role of particle size and charge on the localization and dynamics of molecules within the crowded and polydisperse bacterial cytoplasm. www.pnas.org/doi/10.1073/...

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Theobald Smith Society @njmicrobe.bsky.social · 24/01/2025

The Mo LAB in Princeton continues to develop the HiTES approach on agar (instead of liquid media) to identify the molecules and their roles in initiating interactions between marine macroalgae and the prevalent Roseobacter group species closely associated with them. www.pnas.org/doi/10.1073/...

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Theobald Smith Society @njmicrobe.bsky.social · 16/01/2025

The Rajsbaum lab at Rutgers finds that host TRIM7 has antiviral effects against SARS-CoV-2 by ubiquitination of the viral M protein, immune response regulation, and IFN signaling modulation. Naturally occurring mutations in the M protein could impact pathogenicity. www.nature.com/articles/s41...

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Theobald Smith Society @njmicrobe.bsky.social · 14/01/2025

Rutgers' Don Schaffner and Stockton University's Cliff Baldwin present models for predicting the time to 3-log, 4-log, and 5-log reduction of Salmonella, E. coli O157:H7, and Listeria monocytogenes in commercially prepared salad dressings. www.sciencedirect.com/science/arti...

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Theobald Smith Society @njmicrobe.bsky.social · 08/01/2025

Jamie Calwell, High Meadows Environmental Institute at Princeton developed a modeling approach to assess Zika virus (ZIKV) transmission risk across Africa. The most populous African cities could become suitable for ZIKV transmission by the end of the century. www.thelancet.com/journals/lan...

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Theobald Smith Society @njmicrobe.bsky.social · 08/01/2025

Pfizer was awarded the National Medal of Technology for developing the Pfizer-BioNTech COVID-19 Vaccine. Theobald Smith Society member Annaliesa Anderson, SVP and Head, Pfizer Vaccine R&D, represented Pfizer at the ceremony. Here's what she said about the award: www.linkedin.com/feed/update/...

Photo shows Arati Prabhakar, Ph.D., Director of the White House Office of Science and Technology Policy (OSTP), awards Pfizer Inc. representatives Annaliesa Anderson (C) and Alejandra Gurtman (R) the National Medal of Technology and Innovation during an awards ceremony at the Eisenhower Executive Office Building in Washington, DC, January 3, 2025. Photo by Ryan K. Morris

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Theobald Smith Society @njmicrobe.bsky.social · 08/01/2025

Theobald Smith Society Lifetime member and 2003 Waksman Honorary Lecturer Bonnie Bassler has been awarded The National Medal of Science. Princeton’s Bonnie Bassler was instrumental in founding a new branch of science centered on quorum sensing. nationalmedals.org/stories/the-...

Photo of Arati Prabhakar, Ph.D., Director of the White House Office of Science and Technology Policy (OSTP), awarding Bonnie L. Bassler the National Medal of Science during an awards ceremony at the Eisenhower Executive Office Building in Washington, DC, January 3, 2025. Photo by Ryan K. Morris

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Theobald Smith Society @njmicrobe.bsky.social · 27/11/2024

Improved Broad Spectrum Antifungal Drug Synergies with Cryptomycin, a Cdc50-Inspired Antifungal Peptide Robert J. Tancer, Siddhi Pawar, Yina Wang, Cristina R. Ventura, Gregory Wiedman, and Chaoyang Xue ACS Infectious Diseases 2024 10 (11), 3973-3993 pubs.acs.org/doi/10.1021/...

An antifungal peptide, Cryptomycinamide (KKOO-NH2), derived from a 9-amino acid segment of the C. neoformans Cdc50 protein. A fungal killing assay indicated that KKOO-NH2 is fungicidal against C. neoformans. The peptide has antifungal activity against multiple major fungal pathogens with a minimum inhibitory concentration (MIC) of 8 μg/mL against C. neoformans and Candida glabrata, 16 μg/mL against Candida albicans and C. auris, and 32 μg/mL against Aspergillus fumigatus.

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