iiinova — where your digital self keeps evolving

Reposted by @nima-jaberi.bsky.social

Anita Donlic @anitadonlic.bsky.social · 16/09/2026

🎉 I'm thrilled to announce that the Ðonlić Lab has officially opened this month in the BMB department @wusm-bmb.bsky.social at @washumedicine.bsky.social! The lab will study how condensates shape RNA interactions, therapeutic activity, and disease progression. And - we're hiring! 👇

donliclab.com

Đonlić Lab

Decoding cellular biochemistry from microscopy: chemical tools, RNA biophysics, and machine learning in condensates.

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Reposted by @nima-jaberi.bsky.social

Matthew Taliaferro @jmtali.bsky.social · 11/06/2026

New paper! How do RNAs "know" where to go inside a cell? We dug into the sequence elements that route RNAs to the right place. It turns out that, in mammals, they're surprisingly massive (>200 nt), multipartite, and wonderfully complicated. 🧵

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Reposted by @nima-jaberi.bsky.social

Anita Donlic @anitadonlic.bsky.social · 05/06/2026

Thrilled to see our Deep-Phase paper now online in @cellcellpress.bsky.social! 🎉 The final version expands Deep-Phase across labeling modalities, adds dual-condensate imaging to dissect pathway specificity, and shows greater robustness to batch effects than classical image-analysis methods.

cell.com

Deep learning of functional perturbations from condensate morphology

A deep learning method quantitatively decodes nucleolar, nuclear speckle, and viral condensate morphology to reveal underlying biochemical states. Applying this framework reveals a previously unrecogn...

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Reposted by @nima-jaberi.bsky.social

Joel Babdor @joelbabdor.bsky.social · 11/03/2026

Even among healthy people, immune systems operate at different baseline levels. In our new Cell paper, we show that these immune states are stable over time and are associated with the gut microbiome. 🧵 @cp-cell.bsky.social #Immunology #SystemsImmunology

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Reposted by @nima-jaberi.bsky.social

Jordy F. Botello @jbotello.bsky.social · 10/03/2026

Some molecular machines, like ribosomes, can persist for long periods of time in cells. Could molecular aging of ribosomes shape how proteins are made? In our new preprint we track ribosomes as they age in cells and uncover unexpected effects on translation (1/10) www.biorxiv.org/content/10.6...

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