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Nieratschker Lab @nieratschkerlab.bsky.social · 02/09/2025

New publication alert! 🚨🧬 Our study examined DNA methylation of PRDM8, a histone methyltransferase, in relation to Borderline Personality Disorder (BPD). We found significant associations with BPD status and symptom severity. Find details at: www.mdpi.com/2076-3425/15...

mdpi.com

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Nieratschker Lab @nieratschkerlab.bsky.social · 08/07/2025

We are thrilled to announce the initiation of a new research collaboration with Mariela Chertoff from the University of Buenos Aires! 🇦🇷🌎 We're hosting Mariela in Tübingen this week to kick our bridge project: "Understanding the Resilience to Stress from Rodents to Humans" with Lydia Kogler

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Nieratschker Lab @nieratschkerlab.bsky.social · 18/02/2025

New study from our lab!🚨: We investigated the epigenetic dysregulation of GDAP1 gene in alcohol use disorder, analyzing DNA methylation and H3K4me3 histone modification before and after treatment. Read more here: www.mdpi.com/1422-0067/26...

mdpi.com

GDAP1 Is Dysregulated at DNA Methylation and H3K4me3 Levels in Alcohol Use Disorder

Alcohol use disorder (AUD) contributes significantly to the global burden of disease. The susceptibility for AUD is mediated through an interaction of genetic risk factors and environmental influences...

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Reposted by Nieratschker Lab

Fabian Streit @fstreit.bsky.social · 15/11/2024

Happy to see this finally online: we investigated the genetic association signal of Borderline Personality Disorder in a GWAS meta-analysis with >12,000 cases. We identified 6 risk loci, and investigated shared genetic risk using genetic correlations and PheWAS www.medrxiv.org/content/10.1...

medrxiv.org

Genome-wide association study of borderline personality disorder identifies six loci and highlights shared risk with mental and somatic disorders

Environmental and genetic risk factors contribute to the development of borderline personality disorder (BPD). We conducted the largest GWAS of BPD to date, meta-analyzing data from 12,339 cases and 1...

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