iiinova — where your digital self keeps evolving

Nick Mark, MD @nickmark.bsky.social · 17/09/2026

Haha no. Just interested in physiology in all its forms.

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Nick Mark, MD @nickmark.bsky.social · 28/02/2026

If you like sci-fi read Hyperion. Trust me. It’s great!

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Nick Mark, MD @nickmark.bsky.social · 27/02/2026

🔥 Hot take: The Pentagon has essentially announced that Claude is so much better than other models that they must have it. Anthropic has signaled that they so much more principled than their competitors, that they can’t. When the Pentagon backs down or loses this is a huge PR win for Anthropic.

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Nick Mark, MD @nickmark.bsky.social · 25/02/2026

Important ECG pattern for trainees to know and recognize, particularly at this time of year.

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Reposted by Nick Mark, MD

Matt Siuba @zentensivist.bsky.social · 23/02/2026

Thrilled to join @nickmark.bsky.social and @askinforair.bsky.social to talk about managing the RV in the ICU YT link here youtu.be/Supq1q7J28w?... Also on your fav podcast platforms

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Nick Mark, MD @nickmark.bsky.social · 30/09/2025

As you can see from the screenshot we had no fun at all catching up!

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Nick Mark, MD @nickmark.bsky.social · 22/08/2025

Ok added another mock brand ICU shirt: Just Tube It. Which is is your favorite?

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Reposted by Nick Mark, MD

mattbalay-dustrude.bsky.social @mattbalay-dustrude.bsky.social · 20/08/2025

Just purchased a norepi shirt! FYI for others interested, the website has additional color options

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Nick Mark, MD @nickmark.bsky.social · 20/08/2025

Added some new “mock brand ICU merch” to the @criticalcaretime.bsky.social store & I think it’s pretty awesome! www.criticalcaretime.com/shop

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Nick Mark, MD @nickmark.bsky.social · 30/06/2025

On the website www.criticalcaretime.com

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Nick Mark, MD @nickmark.bsky.social · 30/06/2025

It's that wonderful time of year when new residents are joining the ICU team! Here are a few of my favorite @criticalcaretime.bsky.social infographics to help you understand key concepts: ⚡️Undifferentiated shock 💉 Vasopressors 😮‍💨 The physiologically difficult airway & 🧪 Metabolic acidosis

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Nick Mark, MD @nickmark.bsky.social · 25/05/2025

🎧 LISTEN Apple podcasts.apple.com/us/podcast/c... Spotify open.spotify.com/episode/5OrI... 📺 WATCH YouTube youtu.be/o2fTTT9U-1c?... 📖 READ Shownotes www.criticalcaretime.com/episodes/ard... 2/2

podcasts.apple.com

49. ARDS Imitators with Drs. Warren & Blagev

Podcast Episode · Critical Care Time · 05/19/2025 · 1h 28m

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Nick Mark, MD @nickmark.bsky.social · 25/05/2025

Do you know about ARDS mimics? These are diseases that *LOOK* like ARDS but have very different treatment: AEP, DAH, OP, HP, EVALI, PJP, AIP, etc. If you care for people with ARDS but this alphabet 🍜 of disease doesn’t immediately ring a 🛎️ you NEED to give this episode a listen! 1/

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Nick Mark, MD @nickmark.bsky.social · 07/05/2025

Vinay Prasad’s appointment to lead the FDA’s CBER division is a disaster for biotech stocks but it’s worse for patients who depend on new therapies. Therapies that Vinay has signaled he won’t approve.

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Reposted by Nick Mark, MD

Millie @thatmillie.bsky.social · 02/05/2025

Wait. So he thinks Covid was just a sudden outbreak of…people dying from not eating well?

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Goodishintent @omnintensivist.bsky.social · 02/05/2025

You have been christened

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Nick Mark, MD @nickmark.bsky.social · 02/05/2025

I work with the best team! Love this battle of the inotrope education: milrinone vs dobutamine. Blue 🔵 or 🔴?

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Nick Mark, MD @nickmark.bsky.social · 02/05/2025

Me: ohh is this chylothorax? Student: who’s Kyle Thorax? Me: obv my new pseudonym..

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Nick Mark, MD @nickmark.bsky.social · 02/05/2025

Is this a ratatouille situation? It would kinda explain a lot.

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Nick Mark, MD @nickmark.bsky.social · 25/04/2025

We talk a lot more about how to put an ETT *IN* than how to take em *OUT*. On this week's @criticalcaretime.bsky.social @askinforair.bsky.social & I talk all things EXtubation. - readiness to exubate - breathing trials - overcoming challenges - addressing cuff leak - plus cases Give it a listen! 1/

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Nick Mark, MD @nickmark.bsky.social · 05/04/2025

I really liked Season 1 of Fallout. One thing that struck me as unrealistic was Vault-Tec’s evil plan: to literally nuke the entire world so they could fundamentally reshape society according to their twisted views. Anyway, it feels pretty realistic after this week…

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Reposted by Nick Mark, MD

Liz Borkowski @lizborkowski.bsky.social · 29/03/2025

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

grants.nih.gov

NOT-OD-25-080: Rescission of the Final Scientific Integrity Policy of the National Institutes of Health

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Rescission of the Final Scientific Integrity Policy of the National Institutes of Health NOT-OD-25-080. OD

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Nick Mark, MD @nickmark.bsky.social · 30/03/2025

Pretty strong personal statement tbh

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Nick Mark, MD @nickmark.bsky.social · 28/03/2025

🥇 Achievement unlocked! Not only is @criticalcaretime.bsky.social the #1 critical care podcast, we’ve surpassed RFK Jr’s misinformationcast in the rankings.

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Nick Mark, MD @nickmark.bsky.social · 22/03/2025

This is the pinnacle of good design.

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Nick Mark, MD @nickmark.bsky.social · 08/03/2025

Person A submits an article. Person B reviews it & rejects it. Then person B changes the author name & submits the article to a different journal where it’s accepted. He claims he attached the wrong file by mistake. 😝 Really great argument for pre-prints! retractionwatch.com/2025/03/06/p...

retractionwatch.com

His manuscript was rejected. Then he saw it published by other authors

A chemist at a university in Pakistan found a surprise when he opened an alert from ResearchGate on a newly published paper on a topic related to his own work. When Muhammad Kashif, a chemist…

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

So the emotional crux of this week’s Severance involves Ms Corbel suckling at a deflated endotracheal tube?

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

Prediction: in a year when everyone is lamenting the #DogeRecession, Trump will be looking for someone to blame. Musk is an obvious choice.

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

I’m strongly supportive of developing Starship; we need a rapidly reusable heavy lift platform to replace the space shuttle. But we can do this without exposing commercial flights to the risks of falling debris. SpaceX should be launching at night & out of Florida not Texas…

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

Also the FAA issuing a ground hold at numerous airports Hopefully this won’t impact POTUS golf game…

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

Once again a lot of flights are getting diverted to avoid falling debris from a Starship explosion

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Nick Mark, MD @nickmark.bsky.social · 07/03/2025

Yikes. Starship tumbling out of control & losing engines.

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Brandon Friedman @brandonfriedman.bsky.social · 05/03/2025

They're going to destroy the Department of Veterans Affairs, specifically the VA healthcare system. Firing this many employees will render it effectively unusable by increasing patient wait times to the point of uselessness.

govexec.com

VA plans to lay off as many as 83,000 employees this year

A leaked memo released Tuesday called for VA to slash its workforce to 2019 levels that were in place before millions of veterans became newly eligible for care.

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The Lincoln Project @lincolnproject.us · 03/03/2025

Atlanta Fed forecasts a -2.8% GDP growth for this quarter. 4 weeks ago it was +3.9%. Trump owns this. bit.ly/3Ddsxim

bit.ly

Atlanta Fed model forecasts nearly -3% GDP growth in first quarter of this year

The Atlanta Fed's GDPNow model updated on Monday.

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Nick Mark, MD @nickmark.bsky.social · 03/03/2025

This may be one of the best forwards to a textbook ever. Very on brand for OB to include the weight & volume of the text…

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Nick Mark, MD @nickmark.bsky.social · 02/03/2025

Is funding for point of care ultrasound (POCUS) endangered because of the anti-woke crusade against “POC”? www.propublica.org/article/ted-... Truly we are living in the dumbest timeline…

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Nick Mark, MD @nickmark.bsky.social · 01/03/2025

@askinforair.bsky.social maybe we should do an episode on bronchial crisis

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Reposted by Nick Mark, MD

Ezra Levin ❌👑 @ezralevin.bsky.social · 28/02/2025

I say again: any Republican in congress with an ounce of integrity would switch parties immediately. They are complicit, sadistic cowards. Every single one.

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Nick Mark, MD @nickmark.bsky.social · 01/03/2025

Non-invasive ventilation is a great term. But I probably wouldn’t use it in someone who was aspirating.

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Nick Mark, MD @nickmark.bsky.social · 01/03/2025

Pulmonologist here. “Bronchial crisis” isn’t a thing. The phrase you are looking for is aspiration or aspiration pneumonia.

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Nick Mark, MD @nickmark.bsky.social · 28/02/2025

The US is experiencing the largest measles outbreak including the first deaths from the disease in decades. RFk Jr - the newly confirmed HHS secretary - believes that this is a big pharma hoax & measles isn’t a deadly disease. We are so screwed.

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Nick Mark, MD @nickmark.bsky.social · 26/02/2025

Musk & his underlings suspended PEPFAR payments despite orders from SecState & the White House to resume them. Suspension of PEPFAR will cause over 14,000 otherwise preventable deaths. pepfar.impactcounter.com After his inevitable split with Trump, Musk & co should be held accountable for this.

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Nick Mark, MD @nickmark.bsky.social · 23/02/2025

Periodic reminder that for most people with vasodilatory shock we should be targeting a MAP > 60 mmHg (not 65). A lower MAP goal was associated with a shortened duration of vasopressors & possibly reduced mortality. With vasopressors, less is truly more. jamanetwork.com/journals/jam...

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