iiinova — where your digital self keeps evolving

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 10/04/2026

New paper alert: @nicglewwe.bsky.social connects the explore exploit tradeoff to cognitive flexibility!! A fun paradox: Female mice in our lab do "better" at this cognitive flexibility task because they commit to exploit behavior sooner In @npp-journal.bsky.social www.nature.com/articles/s41...

nature.com

Sex-biased computations underlying differential set shift performance in mice - Neuropsychopharmacology

Neuropsychopharmacology - Sex-biased computations underlying differential set shift performance in mice

0206

Nic Glewwe @nicglewwe.bsky.social · 04/04/2025

Super excited to have my first, first authored paper in preprint! If you’re interested in sex-biased individual differences, cognitive flexibility, or cool mouse tasks, this one’s for you 🐭🧠

171

Reposted by Nic Glewwe

Alicia Izquierdo @aliciaizquierdo.bsky.social · 04/04/2025

✨smart 🐁 experiments… read 🧵👇

162

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 04/04/2025

Second, a few months ago we found that you can actually use the precise coordinates of a touchscreen response as a clue to the latent cognitive state of the animal, and of course once again female mice are more systematic. Provisionally accepted for publication so more soon bsky.app/profile/bior...

2316

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 04/04/2025

Firsties, we developed a cool operant set shift task in the touchscreens for meeces, they can do many shifts in a single session The kicker is female mice do better because they figure out how to follow two rules at once bsky.app/profile/bior...

1409

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 04/04/2025

Hi everyone, the lab has been enabling my professional interest in doing weird shit with touchscreens (as opposed to my personal interest) Blessed are the mice, for they cannot doomscroll but here's some recent work you may enjoy if you want to see what mice do with their touchscreens instead

26512

Reposted by Nic Glewwe

Angeline J. Dukes, PhD @heydrdukes.bsky.social · 07/03/2025

Snippets of my #StandUpForScience speech at the Minnesota State Capitol 🧪🧬 🧠 #ScienceIsForEveryone ✨ #ScienceNotSilence #BlackInNeuro ✊🏾

23877158

Reposted by Nic Glewwe

christine liu / two photon art @christineliu.art · 22/01/2025

Black in Neuro was built in 2020. nothing can stop good work when good people come together We have to keep sticking up for each other and leading things we believe in!!

07120

Reposted by Nic Glewwe

Jess McLaughlin, PhD (they/them) @jfmclaughlin92.bsky.social · 20/01/2025

Sooooo if this whole "biological sex" EO is really happening, biologists are going to make as much noise about it as possible, right? Professional societies, universities, individual research groups? It's really incumbent on us (that's a "biologists us" here) to make a BIG FUCKING STINK

282306666

Reposted by Nic Glewwe

Alik Widge @alikwidge.bsky.social · 18/12/2024

Out today: cross-species improvement of cognitive flexibility www.science.org/doi/10.1126/... The TLDR: remember when we improved human cognition with deep brain stimulation? (pubmed.ncbi.nlm.nih.gov/34725508/) Well, now we did it in rats, and it works the same! Specifically... 1/

science.org

Striatal stimulation enhances cognitive control and evidence processing in rodents and humans

Developing an animal model of human brain stimulation therapy reveals that striatal DBS enhances the brain’s ability to process conflicting evidence.

24119

Reposted by Nic Glewwe

Angeline J. Dukes, PhD @heydrdukes.bsky.social · 03/12/2024

Hi 👋🏾 I’m Dr. Angeline Dukes - daughter of Haitian & Trinidadian immigrants 🇭🇹 🇹🇹, proud #HBCU alumna 💙💛, AND #ForbesUnder30 Social Impact honoree 🙌🏾 Always grateful for #BlackInNeuro and the incredible community we’ve grown together ✨ #BlackSky #NeuroSkyence

2320532

Nic Glewwe @nicglewwe.bsky.social · 21/11/2024

Introduce yourself with your worst feedback from school: I’m Nic and I must plagiarize my writing because I use too many big words that I shouldn’t understand. Courtesy of my 5th grade teacher (ftr, I did not commit the crimes she accused me of 😤)

120

Reposted by Nic Glewwe

Giuseppe Gangarossa 🧠👨‍🔬🏳️‍🌈🇪🇺 @peppeganga.bsky.social · 17/11/2024

Here a "LGBTQ+ 🏳️‍🌈 in Neurosciences" starter pack. Do not hesitate to share and if you identify yourself within this community raise you hand and you'll be added 😀🏳️‍🌈. Together we're stronger! go.bsky.app/UxfGB3u

368540

Nic Glewwe @nicglewwe.bsky.social · 14/11/2024

Re-posting because I can finally tag her! Welcome to bluesky @nquintus.bsky.social !! 🎉💜

161

Reposted by Nic Glewwe

Ben Saunders @bensaunders.bsky.social · 05/10/2024

If you're interested in a neuroscience PhD and will be as #sfn24 #sfn2024 swing by the University of Minnesota Graduate Program in Neuroscience booth at the grad fair. Also check out the linked itinerary below for a list of presentations by current students at the meeting!

0119

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 10/07/2024

A real pleasure to talk with The Transmitter about our recent perspective on being less binary when thinking about sex mechanisms in cognition!! Read if you like hearing me rant (I know you do) or want to get your mind blown (natural consequence of my rants) www.thetransmitter.org/sex-differen...

thetransmitter.org

Accounting for a mosaic of sex differences: Q&A with Nicola Grissom

Breaking the binary view of sex traits can enable researchers to represent the broader complexity of behavior and cognition.

11712

Nic Glewwe @nicglewwe.bsky.social · 28/06/2024

Two fresh neuroscience PhD candidates! I passed my oral prelim the same day as one of my grad school besties 🎉

Two friends posing for a photo against a brick wall. A short pal with tattoos and a black shirt on the left (me), and a tall woman wearing a purple dress on the right (my grad school bestie, Nicole). Both wearing glasses and smiling.

3321

Reposted by Nic Glewwe

Sarah Tuttle @niais.cryptoanarchy.network · 11/06/2024

This is where the current University positions fall apart. We can't speak out against the genocide because that's antisemitic because it is opposing Israel & Israelis might be sad - but Israelis are *also* speaking out against the genocide & we are punishing them too... Who are we protecting?

39750

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 20/05/2024

Very happy to announce our paper! "Sex mechanisms as nonbinary influences on cognitive diversity" A pleasure to contribute to this special issue of Hormones and Behavior about how to be less binary and more inclusive in behavioral and cognitive neuroscience www.sciencedirect.com/science/arti...

Figure from our paper about nonbinary interpretations of sex differences in cognition, describing two suggestions. First, consider assessing strategies instead of performance, and second, consider whether sex impacts are variable and mosaic

15322

Reposted by Nic Glewwe

Nicola Grissom @nicolagrissom.bsky.social · 20/05/2024

NEUROSCIENTISTS, stop pretending to work and read this: Have you ever worried about finding sex differences in your data? Or found a sex difference that led to concerns over mechanism, or worse, overly binary or potentially sexist interpretations? We wrote this for you 🧠 #neuroskyence #academicsky

32619

Reposted by Nic Glewwe

emeritrix @emeritrix.bsky.social · 06/12/2023

Pandemic Mitigation Collaborative estimate of USA Covid-19 levels based on wastewater data. Report for December 4, 2023. Click through for all the bad news. www.pmc19.com/data/index.php

Pie chart: There is more COVID-19 transmission today than in 88.9 percent of the pandemic.

085

Reposted by Nic Glewwe

simón(e) 🌑 @simonedsun.bsky.social · 17/11/2023

The sex binary is dead! Long live sex diversity & variability! Sex is one of the greatest sources of variation seen in life. How do we advance the scientific study of sex across the animal kingdom? Read our latest article in Hormones & Behavior to find out! 🧪 🧠 #neuroskyence

Fig. 1. Dynamic sex variability - An integrative, multidimensional framework. A framework that centers sex variability will enable the study of sex across multiple levels of biological analysis (colored boxes). A) Visual schematic representing the degree of sex variability (y-axis) across biological scale (x-axis) and time (z-axis), with example sex variables of interest (not all possible covariates and functional relationships are presented). In this example, to decipher mechanisms linking gonadal hormones to receptive reproductive behavior in adult rodents (lordosis), the functional relationships (black subset of possible gray relationships) between select variables (bold words) need to be identified. At each level of analysis, numerous variables differ across sex to contribute to reproductive behavior through these functional interactions. Importantly, the degree of variability across sex categories is dynamic and is affected by developmental stage, experience, and environment.

Fig. 2. Approaches for the statistical analysis of sex-associated traits. Flow chart of example approaches for analyzing datasets with sex-associated variables. These analyses answer questions about whether and how sex-associated variables explain variation in dependent variables of interest, how independent variables of interest explain variation in dependent sex-associated variables, and how sex-associated variables (within and/or across levels of analysis) relate to one another. The examples match those in the text where possible, but the approaches are widely applicable and flexible. The choice(s) of analyses should follow directly from the research question(s), and it is likely that multiple approaches will be used in the analysis of an integrative dataset.

Fig. 3. Questions for evaluating frameworks and approaches which study sex variability and diversity. Here, we present a set of questions to ask when critically evaluating work (whether it is your own or others) that addresses sex diversity and variability. Note that these questions reflect the integration of the conceptual framework, experimental approaches, and analysis and interpretation, as each of these aspects informs the other.

420981