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Neurobiology of Aging

@neurobiology-aging.bsky.social
94 followers 148 following 68 posts

NBA publishes behavioral, biochemistry, cell biology, endocrinology, molecular biology, morphology, neurology, neuropathology, pharmacology, physiology and protein chemistry studies of aging or diseases associated with age.

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Neurobiology of Aging @neurobiology-aging.bsky.social · 13/10/2026
✨ SHINY NEW PAPER ✨ Extending single-marker approaches, distinct networks of blood inflammation markers reveal strong relations to age, sex, and CSF Aβ42/Aβ40. www.sciencedirect.com/science/arti...
sciencedirect.com
Relation of blood-based inflammation conditional networks to key immune health status and Alzheimer’s biomarkers in aging adults
Blood inflammatory marker studies in aging and Alzheimer’s disease (AD) research have faced numerous interpretative and methodological challenges that…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 06/10/2026
📚 NEW ISSUE 📚 Articles cover blood-based inflammation markers, gene expression patterns, cannabis exposure, social enrichment, and multilingualism in aging and Alzheimer's Disease, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 29/09/2026
✨ SHINY NEW PAPER ✨ Whereas poorer sleep quality in older adults was associated with lower salience network connectivity, in older women it was associated with higher default network connectivity. @sepehrgourabi.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Sleep quality is associated with default mode and salience network connectivity differently across age and sex
Aging and biological sex are critical moderators of sleep quality, which contributes significantly to age-related cognitive decline and Alzheimer’s di…
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Reposted by Neurobiology of Aging
Rik Henson @rhens.bsky.social · 25/09/2026
1/2 Was fun to work with @lihuaxia.bsky.social on this paper on bilingualism in special issue of @neurobiology-aging.bsky.social on brain resilience in aging and dementia, where we used the valuable #HABS-HD cohort
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Neurobiology of Aging @neurobiology-aging.bsky.social · 23/09/2026
✨ SHINY NEW PAPER ✨ Spectral fluorescence microscopy of post-mortem hippocampal subfield tissue reveals different amyloid polymorphs in cognitively normal and Alzheimer’s Disease brains. @tammarynlashley.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 16/09/2026
✨ SHINY NEW PAPER ✨ Machine learning classifiers trained on PET and MRI data predicted whether individuals with preclinical AD progressed to mild cognitive impairment or dementia. @briangordon81.bsky.social www.sciencedirect.com/science/arti...
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Neurobiology of Aging @neurobiology-aging.bsky.social · 09/09/2026
📚 NEW ISSUE 📚 Articles cover PET and MRI biomarkers of cognitive decline, amyloid polymorphisms in aging and AD, relations between sleep quality and functional connectivity, the role of GABA in neural distinctiveness, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/165/suppl/C
sciencedirect.com
Neurobiology of Aging | Vol 165, Pages 1-92 (September 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 02/09/2026
✨ SHINY NEW PAPER ✨ Astrocyte activatiton (higher plasma GFAP) and genetic risk for Alzheimer's Disease (APOE-ε4) were independently associated with more severe AD biomarkers (Aβ and tau aggregation) and worse cognition. www.sciencedirect.com/science/arti...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 26/08/2026
✨ SHINY NEW PAPER ✨ Higher polygenic risk scores for hand grip strength related to better global cognitive performance measured cross-sectionally and longitudinally. www.sciencedirect.com/science/arti...
sciencedirect.com
Genetic predisposition to hand grip strength predicts cognitive decline
Hand grip strength (HGS) is a predictor of cognitive decline in aging. To understand the direct and indirect mechanisms underlying this association, w…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 18/08/2026
✨ SHINY NEW PAPER ✨ Relative to younger adults, pupil dilation was not associated with memory performance in older adults and their attenuted phasic pupil responses may reflecting impaired locus coeruleus modulation with age www.sciencedirect.com/science/arti...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 10/08/2026
✨ SHINY NEW PAPER ✨ Using @ukbiobank.ac.uk data, aorta and carotid artery structure mediated effects of cardiovascular risk factors (strongest for total cholesterol) on rates of brain aging measured with longitudinal neuroimaging www.sciencedirect.com/science/article/pii/S019745802600059X
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Neurobiology of Aging @neurobiology-aging.bsky.social · 04/08/2026
📚 NEW ISSUE 📚 Articles cover links between epigenetic age and motor impairment, GFAP and APOE e4, handgrip and cognitive decline, pupil dynamics and memory, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 28/07/2026
✨ SHINY NEW PAPER ✨ When brain Age Gap (BAG) incorporates metabolic and physiological blood test parameters, it is more strongly associated with amyloid-β accumulation and cognitive function www.sciencedirect.com/science/arti...
sciencedirect.com
Exploratory analysis of the associations of the brain age gap with cognitive function and amyloid-β accumulation: participants selection based on metabolic and physiological blood markers
The brain age gap (BAG) is defined as the difference between brain age estimated from MRI using artificial intelligence and chronological age, and has…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 20/07/2026
✨ SHINY NEW PAPER ✨ More ferritin-positive microglia that cluster near vasculature in MCI and AD suggests that early microglia activation in response to vascular injury may be a precursor to local neuritic tau development. www.sciencedirect.com/science/arti...
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Neurobiology of Aging @neurobiology-aging.bsky.social · 13/07/2026
✨ SHINY NEW PAPER ✨ Diffusion Tensor Imaging along the Perivascular Space (DTI-ALPS) may reflect local tissue fluid changes and microstructural damage in small vessel disease following stroke www.sciencedirect.com/science/arti...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 07/07/2026
📚 NEW ISSUE 📚 Articles cover dopaminergic degeneration in Parkinson's Disease, brain age gap in relation to cognition and amyloid accumulation, diffusion imaging of small vessel disease, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 163, Pages 1-64 (July 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 01/07/2026
✨ SHINY NEW PAPER ✨ PET study shows that serotonergic and glutamatergic receptor–dense regions may have a preferential metabolic vulnerability in Alzheimer’s Disease www.sciencedirect.com/science/arti...
sciencedirect.com
Neurotransmitter landscape and neurodegeneration patterns in Alzheimer’s Disease
Alterations of neurotransmitter systems in Alzheimer’s Disease (AD) remain partially understood, mainly due to the complexity of simultaneously and di…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 23/06/2026
✨ SHINY NEW PAPER ✨ Sex-specific factors may explain why older women are overrepresented in observational research and men are overrepresented in clinical trials. @mcgill.ca www.sciencedirect.com/science/arti...
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Neurobiology of Aging @neurobiology-aging.bsky.social · 15/06/2026
✨ SHINY NEW PAPER ✨ Category learning performance in older adults is better explained by a prototype than exemplar model even though they engaged the hippocampus and prefrontal cortex similarly to younger adults www.sciencedirect.com/science/arti...
sciencedirect.com
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Neurobiology of Aging @neurobiology-aging.bsky.social · 11/06/2026
✨ SHINY NEW PAPER ✨ A new open dataset is being created to probe biological, psychological and sociocultural aspects of resilience in the aging brain. @shen4brains.bsky.social @alexwiesman.bsky.social @ar0mcintosh.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
The Brain Resilience Study protocol: Building a dataset of the biological and sociocultural factors affecting brain health in older adults
Dementia arises from a complex interplay of biological, psychological, and sociocultural factors. However, previous large-scale studies have largely f…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 02/06/2026
📚 NEW ISSUE 📚 Articles cover effects of sodium intake on memory in aging, altered neurotransmitter systems in Alzheimer's Disease, biological and sociocultural factors affecting brain aging, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 162, Pages 1-80 (June 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 27/05/2026
✨ SHINY NEW PAPER ✨ In older adults, higher daily step counts is associated with better executive functioning and fewer depressive symptoms www.sciencedirect.com/science/arti...
sciencedirect.com
Concurrent associations between visit-to-visit changes in actigraphy-based physical activity and cognitive aging in older adults
Physical activity (PA) is associated with lower dementia risk, yet few studies examine objectively measured PA with concurrently measured brain and co…
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Reposted by Neurobiology of Aging
Sepehr Gourabi @sepehrgourabi.bsky.social · 23/05/2026
Our new paper is out in Neurobiology of Aging! @neurobiology-aging.bsky.social We examined how sleep quality is linked to resting-state brain connectivity across age and sex.Special thanks to Dr.Ian McDonough and our collaborators at The University of Alabama. www.sciencedirect.com/science/arti...
sciencedirect.com
Sleep quality is associated with default mode and salience network connectivity differently across age and sex
Aging and biological sex are critical moderators of sleep quality, which contributes significantly to age-related cognitive decline and Alzheimer’s di…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 19/05/2026
✨ SHINY NEW PAPER ✨ Scoping review of blood biomarkers of frailty and cognitive decline @krockdoc.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Blood biomarkers of frailty and cognition: A scoping review
Frailty increasingly is recognized as a factor that modifies the relationship between disease biomarkers, including neuropathology, and dementia expre…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 12/05/2026
✨ SHINY NEW PAPER ✨ Lower frontal white matter hyperintensities predicted better executive function outcomes in vascular MCI participants treated with N-acetylcysteine and exercise @kristalanctot.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Frontal white matter hyperintensity burden predicts cognitive response to N-acetylcysteine and exercise in vascular mild cognitive impairment
Vascular mild cognitive impairment (vaMCI) is a prodromal stage of dementia defined by cognitive deficits due to cerebrovascular disease. Increased wh…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 04/05/2026
📚 NEW ISSUE 📚 Articles cover blood biomarkers of frailty, MTL network flexibility in older African Americans, actigraphy-based physical activity in aging, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 161, Pages 1-82 (May 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 28/04/2026
✨ SHINY NEW PAPER ✨ A resting-state EEG marker of cortical excitation-inhibition balance (aperiodic exponent) moderated effects of age on episodic and short-term memory @allyneuro.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Resting-state EEG aperiodic exponent moderates the association between age and memory performance in older adults
Memory functions are susceptible to age-related cognitive decline, making it essential to explore the underlying neurophysiological mechanisms that co…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 20/04/2026
✨ SHINY NEW PAPER ✨ Longitudinal growth rate of white matter hyperintensities (WMH) increases with baseline beta-amyloid burden, but decreased with anti-hypertensive medications www.sciencedirect.com/science/arti...
sciencedirect.com
Regional growth rates of white matter hyperintensities are associated with beta-amyloid burden
There is increasing evidence for an association between white matter hyperintensities (WMH) and brain beta-amyloid deposition. How WMH are longitudina…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 14/04/2026
📚 NEW ISSUE 📚 Articles cover white matter hyperintensities in relation to cognitive reserve and amyloid burden, light sensitivity in AD, oligodendrogenesis in the aging brain, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 160, Pages 1-86 (April 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 07/04/2026
✨ SHINY NEW PAPER ✨ Whereas the volume of white matter hyperintensities (WMH) typically increases with age and disease, WMH volume can also decrease @wilcocklab.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
White matter hyperintensity regression: Fact or artifact?
White matter hyperintensities (WMH) are an MRI-based biomarker associated with aging, Alzheimer’s disease, and vascular dementia. Although the volume …
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Neurobiology of Aging @neurobiology-aging.bsky.social · 30/03/2026
✨ SHINY NEW PAPER ✨ Iron overload in the aging mouse brain was linked to higher amyloid beta (Aβ) plaque aggregation and worse working memory www.sciencedirect.com/science/arti...
sciencedirect.com
Excess iron may accelerate amyloid beta accumulation in the brains of older mice
Aging is a natural physiological process that may be accompanied by pathological changes, particularly in the brain. Iron is an essential trace elemen…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 23/03/2026
✨ SHINY NEW PAPER ✨ Evidence of locus coeruleus-noradrenaline (LC-NA) hyperactivity in older adults using behavioral, pupil and EEG data @maramather.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Electroencephalography, pupillometry, and behavioral evidence for locus coeruleus-noradrenaline system related tonic hyperactivity in older adults
Neuroimaging studies have shown that age-related dysregulation of the locus coeruleus-noradrenaline (LC-NA) system is associated with cognitive declin…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 16/03/2026
✨ SHINY NEW PAPER ✨ Time-restricted feeding in mice reduced age-related hippocampal inflammation and social withdrawal, but had no effect on weight @louise-ince.bsky.social @fonken.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Time-restricted feeding rescues sociability deficits and reduces neuroinflammation in aged mice
The aging brain exhibits an increased inflammatory potential which in turn elicits behavioral changes e.g., social withdrawal. Social isolation is a r…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 09/03/2026
📚 NEW ISSUE 📚 Articles cover effects of time-restricted eating on inflammation, locus coeruleus hyperactivity, and iron-related amyloid accumulation in aging, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 159, Pages 1-88 (March 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 03/03/2026
✨ SHINY NEW PAPER ✨ Childhood maltreatment modulates (increases and decreases) the effect of age on gray matter volume and moderates the association between age and executive function www.sciencedirect.com/science/arti...
sciencedirect.com
Childhood maltreatment alters associations between age and neurocognitive health metrics in community-dwelling adults
To further understand whether childhood maltreatment (CM) is associated with indicators of accelerated cognitive aging, this study investigated whethe…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 23/02/2026
✨ SHINY NEW PAPER ✨ Lower tNAA/mIns in hipocampus and posterior cingulate was associated with higher p-tau181/Aβ42 and p-tau181 and lower Aβ42/40 www.sciencedirect.com/science/arti...
sciencedirect.com
1H-MR spectroscopy biomarkers are associated with plasma-derived biomarkers of amyloid-β and tau in the early phase of AD continuum
The objective of the study was to evaluate the relationship of plasma biomarkers of Alzheimer’s disease (AD) with in vivo proton magnetic resonance sp…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 17/02/2026
✨SHINY NEW PAPER ✨ High depressive symptoms in a diverse cohort of healthy control and MCI participants were linked to higher plasma NfL and p-tau181 levels, but not Aβ42/40 www.sciencedirect.com/science/arti...
sciencedirect.com
Depressive symptoms and plasma AT(N) biomarkers among cognitively healthy and mild cognitively impaired in a diverse cohort
Depression is a known risk factor for dementia and MCI, but its associations with AT(N) biomarkers remain inconsistent and may differ by cognitive sta…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 10/02/2026
✨ SHINY NEW PAPER ✨ Atlases for tau-PET staging can be optimized by segmenting in native space and smoothing at 6mm www.sciencedirect.com/science/arti...
sciencedirect.com
Optimized atlas for early tau-PET staging via native space segmentations
Positron Emission Tomography (PET) early Braak staging might be susceptible to anatomical variability and atrophy in the medial temporal lobe (MTL) st…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 03/02/2026
📚 NEW ISSUE 📚 Articles cover optimized atlases for tau-PET staging, depressive symptoms and MR spectroscopy biomarkers of early AD, and more. www.sciencedirect.com/journal/neur...
sciencedirect.com
Neurobiology of Aging | Vol 158, Pages 1-52 (February 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 27/01/2026
✨ SHINY NEW PAPER ✨ Across 3 datasets (3000+ participants), GFAP in both CSF and plasma consistently mediated the effect of age on cognitive impairment and dementia (MCI/AD incidence) www.sciencedirect.com/science/arti...
sciencedirect.com
Identifying a proteomics signature of cognitive impairment and dementia in blood and cerebrospinal fluid through a mediation analysis framework
This study aimed to identify CSF and plasma proteins that mediate the association between age and mild cognitive impairment (MCI) and Alzheimer’s dise…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 20/01/2026
✨ SHINY NEW PAPER ✨ Treatments targeting inflammation (DHCA) and neuronal activity (Mal-gluc) significantly improved recognition memory in 3xTg-AD mice, but did not reduce p-Tau or Aβ burden www.sciencedirect.com/science/arti...
sciencedirect.com
Targeting neuronal activity and neuroinflammation for the treatment of Alzheimer’s disease in a mouse model
Alzheimer’s disease (AD) is characterized by progressive cognitive decline driven by complex pathological processes, including tau hyperphosphorylatio…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 12/01/2026
✨ SHINY NEW PAPER ✨ Tau relates to MR spectroscopy estimates of N-acetylaspartate and myo-inositol in cognitively-unimpaired amyloid-positive adults @elizabethhead.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Hippocampal 1H-MR spectroscopy metabolites are linked to CSF tau pathology in cognitively unimpaired older adults along the Alzheimer’s continuum
Relationships between Alzheimer’s disease (AD) pathologies in cognitively unimpaired adults and in vivo neurometabolic properties measured directly fr…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 06/01/2026
✨ SHINY NEW PAPER ✨ MRI-based diffusion metrics are higher in aged macaques in the central tegmental tract, an ascending projection from the locus coeruleus www.sciencedirect.com/science/arti...
sciencedirect.com
Microstructural changes in locus coeruleus-cortical projections in aged bonnet macaques are independent of myelin loss
The locus coeruleus (LC) is a brainstem nucleus best known for being the primary site of noradrenaline production for the forebrain and is involved in…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 05/01/2026
📚 NEW ISSUE 📚 Articles cover age-related structural differences in the fischer brown Norway rat and bonnet macaques, apraxis deficis in Alzheimer's Disease, proteomic markers of aging, and more. www.sciencedirect.com/journal/neur...
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Neurobiology of Aging | Vol 157, Pages 1-126 (January 2026) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 30/12/2025
✨ SHINY NEW PAPER ✨ Markers of cerebral small-vessel disease (white-matter lesions, lacunes) and vascular risk (e.g., hypertension, BMI) relate to faster 5-year decline in striatal dopamine (DRD2) @lipmpib.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Cerebral small-vessel disease severity, hypertension, and body mass index forecast striatal dopamine D2-receptor decline rates in aging
Normal aging is associated with decline in dopamine function. Factors associated with individual differences in dopamine decline rates remain unclear …
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Neurobiology of Aging @neurobiology-aging.bsky.social · 22/12/2025
✨SHINY NEW PAPER ✨ Higher pulse wave velocity is associated with white matter microstructural damage in older adults 12 years later www.sciencedirect.com/science/arti...
sciencedirect.com
High estimated pulse-wave velocity is associated with lower brain white matter microstructural integrity twelve years later
High pulse wave velocity (PWV), a measure of increased arterial stiffness, is a risk factor for cerebrovascular disease. PWV can be estimated (ePWV) f…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 15/12/2025
📚 NEW ISSUE 📚 Articles cover pulse-wave velocity, cerebral small vessel disease, choroid plexus volume, hearing loss, and racial discrimination in aging, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/156/suppl/C
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Neurobiology of Aging | Vol 156, Pages 1-180 (December 2025) | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Aging at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Neurobiology of Aging @neurobiology-aging.bsky.social · 08/12/2025
✨ SHINY NEW PAPER ✨ Repeated MRI measures of brain volume can help detect later conversion to AD/FTD www.sciencedirect.com/science/article/pii/S0197458025001265
sciencedirect.com
Repeated brain MRI utility in identifying neurodegenerative disorders at the pre-dementia stage
Despite the increasing availability of biomarkers in clinical settings, diagnosing individuals with subtle cognitive/behavioral symptoms and normal st…
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Neurobiology of Aging @neurobiology-aging.bsky.social · 05/12/2025
✨ SHINY NEW PAPER ✨ MRI-derived regional volume and thickness are stronger predictors of cognitive decline, especially for memory, but plasma biomarkers do add predictive value www.sciencedirect.com/science/article/pii/S0197458025001137
sciencedirect.com
Integrating plasma, MRI, and cognitive biomarkers for personalized prediction of decline across cognitive domains
Plasma biomarkers are associated with cognitive performance and decline in Alzheimer’s disease, making them promising for early detection. This study …
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Neurobiology of Aging @neurobiology-aging.bsky.social · 03/12/2025
✨ SHINY NEW PAPER ✨ WMH in the temporal lobe relate to early cortical thinning in AD, beyond what is expected due to amyloid and tau @leoriki3.bsky.social @compneurology.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001216
sciencedirect.com
White matter hyperintensities contribute to early cortical thinning in addition to tau in aging
White matter hyperintensities (WMH) are associated with cortical thinning in distant brain regions. However, it is currently unclear how WMH affect ne…
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