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Neufeldt Lab

@neufeldtlab.bsky.social
123 followers 143 following 5 posts

Organic and organometallic research at Montana State University. Established 2016. Mostly student-run account. Our views are our own.

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Neufeldt Lab @neufeldtlab.bsky.social · 26/08/2026
The Neufeldt lab is looking to hire a postdoc for an experimental position (organic/organometallic chemistry): jobs.montana.edu/postings/52714
jobs.montana.edu
Postdoctoral Research Associate
The Neufeldt Lab is looking for a motivated postdoc to complete a federally funded chemistry research project.
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Neufeldt Lab @neufeldtlab.bsky.social · 23/03/2026
Reveal your fate as a dihaloarene in cross-coupling. Will you retain a halide, or will you lose both of your halides in a double reaction? Roll the ligand and solvent dice to determine—but remember, the rules are different for aryl chlorides and bromides! [Cover art by co-author Matthew Sandin.]
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Neufeldt Lab @neufeldtlab.bsky.social · 23/03/2026
Nate and Matt provide new mechanistic insight into over-arylation in Suzuki cross-couplings, and the surprising differences between dibromo vs. dichloroarenes. Currently free to read as an ACS editor's choice. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Selectivity for Exhaustive Cross-Coupling of Dihaloarenes Is Affected by the Interplay between the Halide Byproduct, Solvent, and Ligand
In dihaloarene cross-couplings, the step(s) that take place after reductive elimination and before the start of the next cycle influence selectivity for monofunctionalization versus difunctionalizatio...
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Neufeldt Lab @neufeldtlab.bsky.social · 12/05/2025
Our C2-selective C—S coupling of 2,4-dichloropyrimidine (work led by Oliver) was highlighted by Synfacts! www.thieme-connect.com/products/ejo...
thieme-connect.com
Thieme E-Journals - Synfacts / Full Text
Thieme E-Books & E-Journals
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Reposted by Neufeldt Lab
Dr. Hotlink @shmemistry.bsky.social · 07/04/2025
english.elpais.com/science-tech...
english.elpais.com
John Hartwig, chemist: ‘The situation for science in the United States is terrible, these are the steps of authoritarian regimes to take power’
The scientist talks to EL PAÍS about the key advances in the production of new pharmaceuticals
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Reposted by Neufeldt Lab
Jenny Yang @chemjen.bsky.social · 28/01/2025
The memo on paused grants is also trying to cancel awarded grants (see last paragraph).
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Neufeldt Lab @neufeldtlab.bsky.social · 24/01/2025
Not that we've been huge social media users, but we're migrating here from X. Latest: C2 selective cross-coupling of 2,4-dichloropyrimidine doi.org/10.1021/jacs... (our "holy grail" substrate for inverting site selectivity) and Sharon receives a PECASE (Biden administration) tinyurl.com/yc3de6e6
doi.org
C2-Selective Palladium-Catalyzed C–S Cross-Coupling of 2,4-Dihalopyrimidines
Under most conditions, 2,4-dihalopyrimidines undergo substitution reactions at C4. Here we report that Pd(II) precatalysts supported by bulky N-heterocyclic carbene ligands uniquely effect C2-selectiv...
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