iiinova — where your digital self keeps evolving

Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 13/08/2026

At today’s #ARTNetSCMeeting, SC Co-Chair Dr. Alan Hutson of @roswellpark.bsky.social shared network updates. Dr. Liron Bar-Peled of MGH Cancer Center and Harvard Medical School gave a fascinating talk on “Identification of Druggable and Redox Vulnerabilities in Cancer.”

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 07/08/2026

At today’s Inflammatory Microenvironment and Tumor Cross-Talk #ARTNetWG meeting, Dr. Samuel McBrayer of Children's Research Institute at UT Southwestern presented on “Metabolite Signaling in the Glioma Microenvironment.”

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 13/07/2026

At today's Functional Screens and Assays #ARTNetWG meeting, Dr. Erik Knudsen of @roswellpark.bsky.social presented an update on the collaborative drug screening project that Roswell Park is conducting with other ARTNet research centers.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 05/06/2026

At today’s Cell States, Metabolism & Inflammatory Microenvironment #ARTNetWGMeeting, Dr. Fatima Mechta-Grigoriou from Institut Curie presented her work on "Spatial determinants of stromal heterogeneity rriving resistance to immunotherapy in cancer".

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 27/05/2026

🚀 Check this out — we’ve launched an AI for Cancer Webinar Catalog, updated weekly! nciartnet.org/en/resources... This curated catalog brings together AI in cancer research webinars from publicly available academic, industry, and professional organizations in one place.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 14/05/2026

At today’s #ARTNetSCMeeting, co-chair Dr. Alan Hutson of @roswellpark.bsky.social provided network updates, and Dr. Ping Mu of @yaleschoolofmed.bsky.social presented how his lab is leveraging AI tools to decode mechanisms of therapy resistance in prostate cancer.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 14/05/2026

🎙️ The inaugural episode of the #ARTNetPodcast is now live theartnetpodcast.riverside.com Join Dr. David Goodrich of @roswellpark.bsky.social & Dr. Jeff Tyner of @ohsuknight.bsky.social as they discuss cancer resistance, tumor evolution, & ARTNet’s mission to advance collaborative resistance research

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/05/2026

At today’s Functional Screens and Assays #ARTNetWGMeeting, Dr. Anton Windfelder from the Fraunhofer Institute for Molecular Biology shared fascinating research on host-pathogen interactions using caterpillars as a model organism. The presentation sparked a highly engaging discussion .

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 09/04/2026

At today’s #ARTNetSCMeeting, Dr. Alan Hutson shared network updates and warmly welcomed new associate member Dr. Jennifer Wargo. Dr. Yu-Ting Chou presented on “Deciphering the interplay of β-catenin/YAP signaling and alveolar lineage plasticity during targeted therapy in #NSCLC.”

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 03/04/2026

At today's Cell States, Metabolism & Inflammatory Microenvironment #ARTNetWGMeeting, Dr. Teresa Zimmers of Oregon Health & Science University presented on “Cancer Cachexia and Treatment Resistance,” sparking a lively and engaging discussion.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 12/03/2026

At today’s #ARTNetSCMeeting, Dr. Alan Hutson provided network updates. Drs. Eric Knudsen and David Goodrich of @roswellpark.bsky.social presented the WG white paper proposal. Dr. Ann-Kathrin Eisfeld of OSU spoke on leveraging constitutional genetic diversity to increase knowledge about AML biology.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 09/03/2026

At today’s Functional Screens & Assay Development #ARTNetWGMeeting, Dr. Molly Ingersoll of @InstitutCochin presented “Mucosal Immunity and Challenges in Treating UTI,” triggering lively discussion.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 06/03/2026

At today's Cell States, Metabolism & Inflammatory Microenvironment WG Meeting, Dr. Dannielle Engle of Salk Institute for Biological Studies shared her work on glycan-driven rewiring of the pancreatic tumor microenvironment.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 06/02/2026

At today's Cell State, Metabolism & Inflammatory Microenvironment #ARTNetWGMeeting, Dr. Nina Grace Steele of University of Cincinnati presented on extracting mechanisms of cellular talk in pancreatic acancer using big data,sparking a lively and engaging discussion.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 08/01/2026

For the scientific presentation, Dr. Ying Huang, from Dr. Michael Hollingsworth’s PCAC U54 team at UNMC, discussed how EV-mediated metabolic reprogramming by MUC1 promotes chemotherapy resistance, sparking a lively discussion. (2/2)

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/12/2025

At today’s #ARTNetSCMeeting, Dr. Heather Lankes introduced NCTN Biobanks: nctnbanks.cancer.gov. Dr. Stephen Lai of H-CARR U54 @mdanderson.bsky.social shared updates on their research quantifying cisplatin sensitivity and resistance using metabolic imaging and circulating tumor cell (CTC) biomarkers.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 13/11/2025

At today's #ARTNetSCMeeting, Dr. Sohail Tavazoie of @rockefeller.edu presented his research on the regulation of #metastasis.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 07/11/2025

Dr. Sandulache is MPI of the #ARTNet H-CARR center 👏👏 This #VeteransDay the NRG Oncology podcast co-hosts sit with NRG Veteran Affairs-Military Treatment Facility Subcommittee Chair Vlad Sandulache to discuss the subcommittee and their goals + clinical research at VA sites. nrgoncology.org/Podcast

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 17/10/2025

The latest issue of the #ARTNet Newsletter is out! It features highlights and reports from the ARTNet Scientific Retreat held in September 2025, along with updates on network progress and ongoing initiatives. indd.adobe.com/view/9af991c...

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 09/10/2025

At today’s Scientific Exchange Meeting, Co-chair Dr. Alan Hutson of @roswellpark.bsky.social shared network updates and welcomed new WG Chairs Drs. Herve Tiriac & Mark Long. Dr. Victoria Seewalt of @cityofhope.bsky.social presented on pregnancy-associated BrCa: TME & field effect. #ARTNetSC

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 19/09/2025

We are pleased to welcome Dr. Herve Tiriac from UC SanDiego as the new vice chair of the ARTNet Inflammatory Microenvironment & Tumor Cross Talk Working Group.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 16/09/2025

Congratulations to Dr. Mark Long from the ARTNet CDMC U24 @roswellpark.bsky.social on being elected co-chair of the Functional Screens & Assay Development WG! The WG is working on leveraging high-throughput methods to understand and combat acquired resistance to therapeutics.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 12/09/2025

Panel Discussion # 2 focused on ARTNet's collaborative approach to translating resistance biology into therapheutic strategies. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 12/09/2025

Cell States, Metabolism and Inflammatory Microenvironment WG shared updates on spatial multi-omics projects tackling therapy resistance in lung, pancreatic & breast cancers, and a joint white paper with PSRC. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 12/09/2025

Dr. Seth Gammon presented updates from the Functional Screens&Assay Development WG. Highlights included a new white paper on targeting acquired resistance, a pilot grant on novel screening & collaborative efforts to uncover shared drug vulnerabilities. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 12/09/2025

Dr. Alan Hutson shared updates from the ARTNet CDMC U24 @roswellpark.bsky.social, featuring new resource-sharing catalogs, collaborative research initiatives, and AI-driven tools to enhance cancer research and foster cross-network collaboration. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Aishwarya Sahasrabudhe from AML U54 @ohsuknight.bsky.social uncovered stromal-driven venetoclax resistance in AML.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Yue Lyu from ARTI U54 @mdanderson.bsky.social integrated scRNA/scDNA data to track radiation resistance in esophageal cancer.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Flash Talks for Poster Presenters featured research with translational potential: Katherine Dempsey from PCAC U54 explored SAT1 & CAF polarization in pancreatic cancer. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

#ESITalk: Dr.Vincent Bernard (ARTI U54) @mdanderson.bsky.social revealed how spatial profiling uncovers persister cell populations and immune reshaping after radiation in pancreatic cancer. Targeting KRAS and ferroptosis/cuproptosis defenses may improve radiosensitivity #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

#ECITalks: Melissa Stewart from AML U54 @ohsuknight.bsky.social shared how combining venetoclax with the CDK4/6 inhibitor palbociclib overcomes resistance in RAS-mutant AML, reducing tumor burden, improving survival, and reshaping protein synthesis pathways. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

#ECITalk: Dr. Moran Amit from H-CARR U54 at @mdanderson.bsky.social shared how tumor-associated nerves drive cancer progression, #metastasis, and therapy resistance. Targeting the neural-tumor microenvironment opens new paths for cancer treatment and #immunotherapy. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

#ECITalk: Dr. Surendra Shukla from ARTNet PCAC U54 shared how BACH1 drives pancreatic cancer progression and FOLFIRINOX resistance. Targeting BACH1, directly or with hemin, enhances therapy efficacy and reveals PDIA6 as a key player in unfolded protein response. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Trever Bivona from BAATAAR-UP center shared findings of how tumor lineages adapt to targeted therapy in EGFR-mutant #lungcancer. Combination strategies such as osimertinib+sonidegib can overcome resistance driven by transcriptional plasticity tinyurl.com/43d6sma4 #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Jeffrey Tyner (ARTNet AML center) highlighted how AML cell differentiation states govern therapy response & resistance. His team developed Myelo-ID, a rapid gene expression test that predicts outcomes & helps guide treatment decisions. Read more: tinyurl.com/kpt3483z #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Jeffrey Myers shared advances in overcoming cisplatin resistance in head & neck cancer, highlighting NRF2-driven resistance, immune suppression, and novel biomarkers like HP-MRI and exosomal miRNAs for precision therapy. More info: nciartnet.org/en/members/h... #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Pankaj Singh shared updates from the Pancreatic Cancer ARTNet Center (PCAC), highlighting metabolic drivers of resistance, MUC1-mediated exosome signaling, and targeting Cyclin K to overcome therapy resistance More on ARTNet PCAC center: nciartnet.org/en/members/p... #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Drs. Boyi Gan & Dadi Jiang from MD Anderson shared advances from the ARTI Center, exploring ferroptosis&other cell death pathways to overcome tumor radioresistance, highlighting CRIP1-PP2A-MTF1 signaling & therapeutic strategies targeting cuproptosis. More on ARTI center: tinyurl.com/y85z5yua

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Panelist Dr. Pankaj Singh highlighted cancer disparities among American Indian and Alaska Native populations, emphasizing systemic inequities, limited tissue access, and lack of models. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Panelist Dr. Chinthalapally V. Rao of OUHealthScience highlighted stark disparities in colorectal cancer among African American & American Indian/Alaska Native populations in Oklahoma, linking molecular differences, inflammation, and access to care to survival outcomes. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Panelist Dr. Victoria Seewaldt of City of Hope presented research on treatment-resistant triple-negative breast cancer, revealing early aggressive tumor microenvironment biology and highlighting complement C3 as a potential target for therapy. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Panelist Dr. Jose Trevino of VCUHealth highlighted efforts to address cancer health disparities through the U4HELPP program and Rapid Autopsy Program, advancing understanding of pancreatic cancer and metastatic disease. #ARTNetScientificRetreat2025 #CancerResearch

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Panel Discussion: Clinical Patterns and Biological Mechanisms of Outcome Disparities and Acquired Resistance. Moderator: Dr. Jeffrey Tyner Panelists: Dr. Jose Trevino, Dr. Victoria Seewaldt, Dr. Chinthalapally V. Rao, and Dr. Pankaj Singh #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

At #ARTNetScientificRetreat2025, keynote speaker Dr. Veronica Galvan Hart, shared insights on how aging and cellular senescence connect Alzheimer’s disease and cancer, highlighting tau-induced senescence and opportunities for early intervention. Learn more about her research: galvanlab.org

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Robert Mannel, Director of Stephenson Cancer Center, introduced the OU Health Stephenson Cancer Center (SCC) #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Dr. Ian Dunn, Executive Dean of the College of Medicine Chief Academic Officer, introduced the University of Oklahoma Health Sceince Center. #ARTNetScientificRetreat2025

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 11/09/2025

Two days of the #ARTNetScientificRetreat2025 are taking place at the University of Oklahoma Health Science Center. hosted by our OUHSC U54 Center PI, Dr. Pankaj Singh.

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 20/08/2025

FYI: @sitcancer.bsky.social and NCI sponsored free webinar focused on assessing TME with systems Immunology,as part of the Computational Immuno-Oncology Series is taking place tomorrow, August 21st at 12 PM ET. Register at: sitcancer.org/CompIO

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Acquired Resistance to Therapy Network (ARTNet) @nciartnet.org · 27/05/2025

How can machine learning unlock insights from multimodal data in immunotherapy? Join the Lessons from the CIMAC-CIDC Network webinar to explore patient heterogeneity and treatment response modeling. 🎓 FREE registration: sitcancer.org/CompIO #SITC #NCI #Immunotherapy #CompIO

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