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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 10/12/2024

Tremendous resource paper from NCI-PSRC member Nina Steele on collating a single cell RNA SEQ dataset in #PancreaticCancer The dataset is now housed with the PSRC. aacrjournals.org/clincancerre...

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 03/12/2024

The semi annual virtual meeting of the NCI PSRC is happening now. Here NCI highlights the top ten papers from the consortium thus far.

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 29/11/2024

The incidence of #PancreaticCancer in women with a BRCA1 or BRCA2 mutation acsjournals.onlinelibrary.wiley.com/doi/10.1002/... The cumulative incidence from age 40 to 80 years was 2.2% for BRCA1 carriers and 2.7% for BRCA2 carriers. Most did not have a family history of the disease.

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 29/11/2024

THE DEFINITIVE AGING ATLAS A panoramic view of cell population dynamics in mammalian aging www.science.org/doi/10.1126/... PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, sexes, and genotypes!

science.org

A panoramic view of cell population dynamics in mammalian aging

To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 28/11/2024

Recent Cancer Discovery paper by NCI-PSRC investigator @hccvpdac.bsky.social ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma aacrjournals.org/cancerdiscov... Important study on regulators of gastric metaplasia in early #PancreaticCancer & classical variant of PDAC.

aacrjournals.org

ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma

The receptor tyrosine kinase ROR2 defines the cellular identity of pancreatic precancerous lesions and confers aggressiveness and therapeutic resistance in cancer.

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 28/11/2024

Multiple NCI-PSRC investigators co-authored this perspective in Cancer Research last month: #PancreaticCancer–Associated Fibroblasts: Where Do We Go from Here? aacrjournals.org/cancerres/ar... @kenolivelab.bsky.social @marasherman.bsky.social @debvendramini.bsky.social @tme-caf-ecm.bsky.social

aacrjournals.org

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 28/11/2024

The #PancreaticCancer starter pack now has over 100 researchers, advocates and organizations engaged in pancreatic cancer research & advocacy. Please write to @anirbanmaitra.bsky.social if you need to be added. This account will maintain an updated feed of pancreatic cancer research moving forward.

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Pancreatic Cancer Stromal Reprogramming Consortium @nci-psrc.bsky.social · 28/11/2024

Please follow the NCI #PancreaticCancer stromal reprogramming consortium on 🦋 Learn more about our program here: www.nci-psrc.org

nci-psrc.org

Pancreatic Cancer Stromal Reprogramming Consortium (PSRC)

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