Nature Communications - I-motifs are non-canonical secondary DNA structures that form dynamically in certain C-rich DNA regions. Here, the authors show that PCBP1 binds and unfolds i-motifs in a...

G-quadruplex (G4) structures are critical regulators of gene expression, yet the role of an individual G4 within its native chromatin remains underexplored. Here, we used CRISPR-Cas9 to introduce guan...

The Department of Medical Biochemistry and Biophysics at Umeå University, Sweden, invites applicants for a two-year Postdoctoral fellowship.

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