I realized that I never posted about this awesome paper, which quantifies contributions of movement, reward anticipation, and timing to cortical and striatal ramping activity:

Johnson Zhang led a study from our work describing new glycolysis-enhancing strategies for yeast and mice that demonstrate neuroprotection in ADNI and large-scale administrative data: Nice story from Iowa:

This is much too late - but congrats to Hannah Stutt for defending her PhD earlier this year. She will join Austin Coley's lab at UCLA.

Land-based spatial mazes are a low-stress method to evaluate learning in rodent models of dementia. By using innate exploratory and hiding behavior, the Barnes maze requires fewer trials, allowing exa...

Mortality is increased in Parkinson’s disease (PD) and is difficult to predict because of its heterogeneity and the availability of few reliable progn…

Background: Parkinson's disease (PD) increases mortality is difficult to predict because of its heterogeneity and the availability of very few reliable which prognostic markers. Objectives: We used el...

Across species, prefrontal and striatal neurons exhibit time-dependent ramping activity, defined as a consistent monotonic change in firing rate across temporal intervals. However, it is unclear if ra...

Researchers have found that amphetamine alters how the brain processes time, increasing variability in the activity of neurons that encode temporal information. The study provides insight into how the...

medRxiv - The Preprint Server for Health Sciences

Prefrontal neurons can have diverse activity during cognitive functions like working memory, attention, and timing; however, the importance of this heterogeneity is unclear. Our goal was to better und...

We demonstrated brain-wide GFP expression driven by Drd1-Flpo, suggesting that this mouse line may be useful for comprehensive anatomical and functional studies in many brain regions. The Drd1-Flpo mo...

Generalizing aversive memories helps organisms avoid danger, whereas discriminating between dissimilar situations promotes opportunistic behaviors. We identified a novel pathway that controls the cont...

Jobs@UIOWA: The official place to search and apply for jobs at The University of Iowa.

medRxiv - The Preprint Server for Health Sciences