We present a case series of 4 single ventricle patients with either native aortic root and/or coronary thrombosis who underwent catheter-directed thrombolysis with recombinant tissue plasminogen activ...

The mechanism of stent failure in acute limb ischemia includes a broad spectrum of thrombotic and mechanical factors. We present a patient with recurring Rutherford Class 2A acute limb ischemia, who u...

Coronary artery obstruction is a rare but life-threatening complication of valve-in-valve transcatheter aortic valve replacement, particularly in patients with externally mounted leaflet bioprostheses...

Health care professionals in fluoroscopic laboratories face significant occupational hazards, including cancer, cataracts, and reproductive concerns due to prolonged exposure to iodizing radiation, an...

The LithiX Hertz Contact Intravascular Lithotripsy System (Elixir Medical) is a new calcium fragmentation device that uses metal hemispheres on a semicompliant balloon to impart high contact stresses ...

Artificial intelligence-based fractional flow reserve (AI-FFR) incorporates a machine learning-based algorithm to derive FFR directly from angiography. Its accuracy compared with invasive FFR has not ...

Clinically significant native aortic regurgitation (AR) increases with age. Surgical aortic valve replacement has been the only curative guideline-recommended therapy, while transcatheter options rema...

Management of obstructive mechanical mitral valve thrombosis in patients with prohibitive surgical risk and contraindication to thrombolytics is not well defined. Transcatheter approaches, such as man...

Cardiogenic shock (CS) is a life-threatening complication of acute myocarditis (MC) and takotsubo cardiomyopathy (TC). Comparative data on mechanical circulatory support (MCS) utilization and outcomes...

Atrial fibrillation (AF) is prevalent among patients undergoing transcatheter aortic valve replacement (TAVR) and increases risks of thromboembolism and bleeding with chronic anticoagulation. Concomit...

Transcatheter aortic valve-in-valve implantation is an established therapy for failed surgical bioprosthetic valves and may obviate the need for reoperative surgery. Despite the routine use of large-b...

Transradial cardiac catheterization is recommended over femoral artery catheterization for patients with acute coronary syndrome due to lower rates of bleeding and vascular complications. Despite its ...

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Geographic challenges complicate treatment of rural patients with ST-elevation myocardial infarction (STEMI), and many undergo a pharmacoinvasive (PI) strategy for optimal STEMI management. The PI pop...

Pulmonary embolism (PE) remains the third leading cause of cardiovascular-related mortality, and few efforts have been made to study it exclusively through real-world registry data. This research show...

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Intravascular imaging (IVI), including intravascular ultrasound and optical coherence tomography, has been associated with improved outcomes when used with angiography-guided percutaneous coronary int...

Residual shunting after transcatheter patent foramen ovale (PFO) closure occurs in up to 25% of patients and increases the risk of recurrent neurologic events. Existing sizing strategies may be insuff...

Dual antiplatelet therapy (DAPT) is well-established for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Contemporary studies demonstrated that a short...

Effective vascular closure is crucial in transfemoral transcatheter aortic valve replacement (TAVR) to minimize access-related complications. Although dual suture-based closure is widely used, a hybri...

The optimal duration of dual antiplatelet therapy (DAPT) for high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI) can vary based on individual clinical and lesion char...

Myocardial infarct size (IS) is a key determinant of long-term outcomes after acute myocardial infarction (MI). Although infusion of supersaturated oxygen (SSO2) after primary percutaneous coronary in...

Peripheral arterial disease often affects the lower extremities, is frequently bilateral, and typically involves multiple leg segments. Symptomatic disease is usually treated endovascularly. Antegrade...

Extended anticoagulation therapy is often required in patients with venous thromboembolism (VTE), but the optimal dosing strategy remains unclear. This study aimed to evaluate the efficacy and safety ...

Pulmonary arterial hypertension (PAH) is a progressive, often fatal disease. Balloon atrial septostomy may relieve symptoms or serve as a bridge to transplant, but carries risks of variable shunting a...

Percutaneous coronary intervention for distal left main bifurcation disease remains technically challenging owing to complex anatomy and high ischemic risk. Although multiple stenting techniques exist...

Radial artery pseudoaneurysm (RAP) is a rare complication of procedural radial access. There is a paucity of data regarding clinical presentation, characteristics, and management.

The Onyx ONE Clear study demonstrated favorable 1-year efficacy and safety outcomes in patients with high bleeding risk (HBR) and 1 month of event-free dual antiplatelet therapy (DAPT) after treatment...

Mitral paravalvular leak (PVL) is a challenging and potentially debilitating complication of prosthetic valve implantation, particularly when it occurs in the setting of prior closure attempts and com...

Transcatheter cardiac interventions have advanced substantially over the past decade, providing less invasive therapeutic options for an expanding spectrum of structural heart disease. As procedural c...

Occupational radiation exposure has a clear association with long-term health effects and has a particular impact on women, trainees, and supporting staff. There is a reliance on limited, traditional ...

Transcatheter aortic valve replacement (TAVR) has transformed the treatment of severe aortic stenosis; however, up to 20% to 30% of patients continue to experience symptoms that limit quality of life ...

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Reducing the number of device exchanges during a left atrial appendage (LAA) closure procedure can minimize the risk of injury, air embolism, and thrombus, and optimize procedural workflow. This study...

The effectiveness of current statin therapy in achieving lipid targets in Indian patients remains uncertain. This observational study aimed to evaluate lipid goal attainment at 1 and 6 months with ato...

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Limited data suggest that transcatheter aortic valve replacement (TAVR) is associated with similar short-term outcomes to surgical aortic valve replacement (SAVR) among patients with a history of medi...

Cardiovascular diseases, particularly coronary artery disease (CAD), remain a leading cause of morbidity and mortality worldwide and in India. In 2022, an estimated 315 million patients (95% uncertain...

This review is based on interviews with internationally recognized female leaders in congenital cardiac interventions. The discussions explore diverse career pathways and professional experiences acro...

Percutaneous coronary intervention of severely calcified coronary lesions is associated with a higher risk of adverse events in women compared with men.

A methodology for predicting pediatric cardiac catheterization-related complications can assist interventionists in planning treatment strategies, obtaining informed consent, and allocating medical re...