This amazing work by my master's student, Börries von Seggern, is out as a preprint! 🎉
We looked at the problem of translating data obtained from cross-linking mass spectrometry into a matrix of interaction potentials between several species in a coarse-grained model.
arxiv.org/abs/2606.05541
arxiv.org
Methods for Inferring Interaction Potentials from Cross-Linking Mass Spectrometry Data
Cross-linking mass spectrometry (XL-MS) has emerged as a powerful quantitative technique for probing intra-protein structural information as well as protein-protein interactions at an unprecedented sc...