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Mohsen Sadeghi

@mohsensadeghi.bsky.social
1.2K followers 861 following 73 posts

computational physicist, pretending to do bio/neuro stuff. Staff Scientist at @zuseinstitute.bsky.social Opinions expressed are solely my own. mohsensadeghi.github.io linkedin.com/in/drmohsensadeghi

PostsRepliesMedia
Mohsen Sadeghi @mohsensadeghi.bsky.social · 05/06/2026
This amazing work by my master's student, Börries von Seggern, is out as a preprint! 🎉 We looked at the problem of translating data obtained from cross-linking mass spectrometry into a matrix of interaction potentials between several species in a coarse-grained model. arxiv.org/abs/2606.05541
arxiv.org
Methods for Inferring Interaction Potentials from Cross-Linking Mass Spectrometry Data
Cross-linking mass spectrometry (XL-MS) has emerged as a powerful quantitative technique for probing intra-protein structural information as well as protein-protein interactions at an unprecedented sc...
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 08/02/2026
Können „Mini-Gehirne“ künftige KI-Anwendungen steuern? background.tagesspiegel.de/digitalisier...
background.tagesspiegel.de
Bioprozessoren: Können „Mini-Gehirne“ künftige KI-Anwendungen steuern?
Start-ups in Deutschland, der Schweiz oder Australien versuchen den Sprung in die „Post-Silizium-Ära“. Sie nutzen Gehirn-Organoide aus echten Zellen zur Datenverarbeitung. Biocomputing könnte das Ener...
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Jana Kroll @janakroll.bsky.social · 13/12/2025
❄️🔬⏱️ I am excited to share that our study „Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons” has been published in Nature Communications www.nature.com/articles/s41... 👇 Short summary of our key findings (1/8)
nature.com
Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons - Nature Communications
Synaptic vesicle fusion is essential for neuronal communication, yet its nanoscale sequence has not been directly confirmed. Here, the authors use timed in situ cryo-electron tomography to visualize t...
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 10/12/2025
It's very important for the character to always find new endeavors in which you can get rejections for fresh reasons.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 16/10/2025
Very important finding: www.science.org/content/arti...
science.org
Chicago’s beloved ‘rat hole’ was actually made by a squirrel
Scientists reopen the case of “splatatouille”
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 03/10/2025
This is quite interesting. Mitochondrial 'DNA expulsion' triggers inflammation pathways. www.nature.com/articles/d41...
nature.com
Mitochondria expel tainted DNA — spurring age-related inflammation
Organelles spit out DNA contaminated with damaging components, leading to the activation of inflammatory enzymes, mouse experiments show.
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Current Biology @currentbiology.bsky.social · 01/10/2025
Sad news: Jane Goodall has died. She did more than any other human for our understanding and appreciation of our closest relatives, the chimpanzees. That chimpanzees are Endangered tells you everything about our species and about what made her so exceptional. www.nytimes.com/2025/10/01/o...
nytimes.com
Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 02/09/2025
Very interesting: people.idsia.ch/~juergen/who...
people.idsia.ch
Who invented convolutional neural networks?
Who invented convolutional neural networks?
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 01/08/2025
Somebody help these poor predators. They are in mortal danger, apparently.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 01/08/2025
When you don't bother to initiate your spam bot:
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Rita Strack @ritastrack.bsky.social · 10/07/2025
Come work at Nature Methods! A dream job. I know from experience 😄
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 25/05/2025
Peak zero-shot learning:
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 17/05/2025
American "Battle Royale"... It's not Onion, and we're comfortably away from 1. April.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 16/05/2025
This is an interesting read. I knew about Nagel's work on coffee stains. And when I read this part, "...I mean, would you give tenure to someone who’s studying coffee stains?" it made me sad. There is less and less room for beauty and curiosity in science. www.quantamagazine.org/finding-beau...
quantamagazine.org
Finding Beauty and Truth in Mundane Occurrences | Quanta Magazine
The physicist Sidney Nagel delights in solving mysteries of the universe that are hiding in plain sight.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 16/05/2025
I'm a bit surprised by these numbers. There's bigger resistance than I would've guessed: www.nature.com/articles/d41...
nature.com
Is it OK for AI to write science papers? Nature survey shows researchers are split
Poll of 5,000 researchers finds contrasting views on when it’s acceptable to involve AI and what needs to be disclosed.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 02/05/2025
One of those days in the lab.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 21/04/2025
Another piece of scientific fact put into question by Trump's administration, where refuting the antiquated idea of biological race called "anti-american idealogy". It is interesting how similar patterns emerge with fascism. www.bbc.com/future/artic...
bbc.com
'Biological reality': What genetics has taught us about race
As US President Donald Trump takes aim at the Smithsonian Institution for "anti-American ideology", Adam Rutherford examines what the science of genetics has taught us about race.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 17/04/2025
www.theguardian.com/commentisfre...
theguardian.com
The Blue Origin flight showcased the utter defeat of American feminism | Moira Donegan
The trip leaned on a vision of women’s empowerment that is light on substance and heavy on a childlike, girlish silliness
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Chris Murphy @chrismurphyct.bsky.social · 03/04/2025
Those trying to understand the tariffs as economic policy are dangerously naive. No, the tariffs are a tool to collapse our democracy. A means to compel loyalty from every business that will need to petition Trump for relief. 1/ A 🧵 to explain his plan and how we fight back.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 30/03/2025
You're my kind of crazy (and old) if you find this coding walkthrough for controlling SID chip in C64 using machine code inside BASIC interpreter where IRQ mapping is used to turn the screen content into a real time music controller, the coolest thing. www.youtube.com/watch?v=ly5B...
youtube.com
Making 8-bit Music From Scratch at the Commodore 64 BASIC Prompt
YouTube video by lftkryo
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 14/03/2025
Leider finde ich es bei den Max-Planck-Instituten weniger überraschend: p.dw.com/p/4rhHK
p.dw.com
Machtmissbrauch an Max-Planck-Instituten – DW – 13.03.2025
Max-Planck-Institute locken mit ihrem Ruf und Top-Forschungsbedingungen. Aber der Nachwuchs wirft Vorgesetzten Mobbing vor. Eine Recherche von DW und "Der Spiegel" zeigt: Beschwerdeverfahren versagen ...
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 14/03/2025
I found this interview with Curtis Yarvin quite helpful in understanding a lot of non-sensical directions the US is headed. I am also genuinely frightened by how hard it has become to state the obvious in the face of the "techno-monarchy" ideas. www.nytimes.com/2025/01/18/m...
nytimes.com
Curtis Yarvin Says Democracy Is Done. Powerful Conservatives Are Listening.
The once-fringe writer has long argued for an American monarchy. His ideas have found an audience in the incoming administration and Silicon Valley.
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openRxiv @openrxiv.bsky.social · 11/03/2025
openRxiv has arrived! We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openrxiv.org/introducing-... #openRxiv #OpenScience #Preprints #bioRxiv #medRxiv
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 05/03/2025
We're stuck on this weird timeline. www.newsweek.com/putin-agrees...
newsweek.com
Putin agrees to help broker talks between Trump and Iran: reports
Russia "is ready to do everything in its power" to help facilitate negotiations between US and Iran.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 28/02/2025
For me, this altercation was the first time a leader of a country acted in front of Trump the way it made sense. Not surprisingly, as is the case with all bullies, it also brought the worst in Trump out. Need more of this. bbc.com/news/videos/...
bbc.com
Watch angry exchange between Trump and Zelensky at White House
The US president accused the Ukrainian leader of being disrespectful in a tense meeting in the Oval Office.
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Lipi Thukral @lipithukral.bsky.social · 15/02/2025
Hello blue sky! Excited to be a part of the scientific community on this platform.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 22/02/2025
OMG, great stand up comedy is going on at CPAC. 🤣
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 13/02/2025
Honored to be part of this amazing work, where synaptic vesicle fusion has been studied by a clever combination of optogenetic stimulation and cryoET. I welcomed the opportunity to contribute with mesoscopic simulations involving dynamic membranes. Preprint: www.biorxiv.org/content/10.1...
biorxiv.org
Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons
During neurotransmission, presynaptic action potentials trigger synaptic vesicle fusion with the plasma membrane within milliseconds. To visualize membrane dynamics before, during, and right after ves...
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Jana Kroll @janakroll.bsky.social · 12/02/2025
Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1... We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 25/01/2025
Some effective eye bleach for weekend use! 😍
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 20/01/2025
I have a bad fever today, so I hope it was all delirium what I just watched and not a sci-fi apocalyptic scene where democracy is superseded by whatever this is going to be. I've been trying very hard to hear the word "democracy" once.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 20/01/2025
Hear me out! The way things go, I believe this journal has huge potential.
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Terra Sztain @terrasztain.bsky.social · 19/01/2025
I made one 🦋
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Fernanda Duarte @fjduarte.bsky.social · 05/01/2025
We are seeking an outstanding #PhD candidate to join our team (www.duartegroupchem.org)! If you know potential candidates interested in combining #ML and #compchem reaction modelling for catalyst design, please share this opportunity with them! 🗓 Deadline: 31/01/25 📥 Application: shorturl.at/nHyAo
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Lotus Lofgren @lotuslofgren.bsky.social · 01/01/2025
Jan 1, and my first day as an Asst. Professor at Berkeley. The lab opens in just a few weeks and I am currently staffing at all levels- www.lotuslofgren.com/new-page-1
lotuslofgren.com
Join our team — The Lofgren Lab
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 29/12/2024
Former US president Jimmy Carter has died, at the age of 100. The Iran hostage crisis was his undoing in 1980, which meant he lost to Reagan for his second term. Some argue that a lot went downhill with US politics and economical imbalance afterwards. bbc.com/news/article...
bbc.com
Obituary: Former US President Jimmy Carter
The US president struggled in the White House and served just one term, but later won a Nobel Peace prize.
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Haucke lab @volkerhaucke-lab.bsky.social · 24/11/2024
....and here are the details for those interested in a postdoc with us...
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Ultan McDermott @ultanmcd.bsky.social · 06/12/2024
Hi - if any newly minted PhD students interested in a 1-year post in AstraZeneca in Cambridge, UK working on drug resistance - please share with your networks. An opportunity to see what it's like in industry. astrazeneca.wd3.myworkdayjobs.com/Careers/job/...
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Grant Rotskoff @grant.rotskoff.cc · 23/12/2024
I am hiring a postdoctoral scholar with a start date summer or fall 2025. Projects will be focused on thermodynamically consistent generative models, broadly defined. If you’re interested, please send a CV and one paragraph about why you think you’d be a good fit to rotskoff@stanford.edu
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Altmetric @altmetric.com · 14/12/2024
“While X currently dominates altmetric mentions, the observed growth on Bluesky suggests a potential shift in the future, underscoring its emerging role in academic dissemination and the challenges of adapting scholarly communication metrics across evolving platforms” #AcademicSky #Altmetrics
arxiv.org
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Frank Noe @franknoe.bsky.social · 11/12/2024
Excited about BioEmu? Opening this position for just a few days over #NeurIPS2024. Looking especially for Bioinformatics + Structural Biology skills, MD/Stat Mech skills and/or #deeplearning architecture design + engineering skills aka.ms/ai4science-r...
aka.ms
Search Jobs | Microsoft Careers
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 06/12/2024
I accept the roast. Persona Analysis: The Academic Comedian with 88% authenticity! blueskyroast.com/roast/mohsen...
blueskyroast.com
Mohsen Sadeghi: The BioPhysics Buff on Bluesky!
Where cutting-edge science meets the art of professional networking, sprinkled with a dash of humor.
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Simon Fisher @profsimonfisher.bsky.social · 05/12/2024
In a @currentbiology.bsky.social paper earlier this year, led by @laurawesseldijk.bsky.social, we analysed Beethoven’s genome with a polygenic index related to musicality, as a way to communicate limits of genetic predictions at the individual level & the complexity of links between DNA & behaviour:
cell.com
Notes from Beethoven’s genome
Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.
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Frank Noe @franknoe.bsky.social · 06/12/2024
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...
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Marco De Vivo @marcodevivo.bsky.social · 05/12/2024
POSTDOC IN MOL SIMULATIONS AND AI Open position in my group, apply here: iit.taleo.net/careersectio... Looking for motivated candidates. 👍💪🥇
iit.taleo.net
Post Doc position in Computational Simulations of proteins and nucleic acids with impact on drug discovery
Fare clic sul collegamento fornito per visualizzare la descrizione completa dell'offerta di lavoro.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 05/12/2024
DeepMind's Genie 2 can now make a 3D game-like environment that responds to movement and action commands (generates new frames from an input image and keystrokes). Their proposed usecase is RL agent training. But add a stereoscopic VR view, and count me an agent! deepmind.google/discover/blo...
deepmind.google
Genie 2: A large-scale foundation world model
Generating unlimited diverse training environments for future general agents
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 04/12/2024
They welcomed the little bot to the reality club! www.kickstarter.com/projects/alb...
kickstarter.com
Rick and Morty™️ Butter Bot: an inspired-by AI-powered robot
Customizable and codable, this interactive robot -inspired by the hit TV show Rick and Morty- comes packed with AI and a dual-core CPU.
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Mohsen Sadeghi @mohsensadeghi.bsky.social · 04/12/2024
Catching up the Amazon way: www.aboutamazon.com/news/aws/ama...
aboutamazon.com
Introducing Amazon Nova, our new generation of foundation models
New state-of-the-art foundation models from Amazon deliver frontier intelligence and industry-leading price performance.
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 03/12/2024
In November, 143 people died of an “unknown disease” in a rural area of Democratic Republic of the Congo. These individuals had flu-like symptoms such as a high fever and severe headaches, and the number of people infected continues to rise.
reuters.com
Unknown disease kills 143 in southwest Congo, local authorities say
An unknown disease killed 143 people in Democratic Republic of the Congo's southwestern province in November, local authorities told Reuters.
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COSMO Lab @labcosmo.bsky.social · 03/12/2024
Hello! I'm posting this both here and on the X-rated site, let's see where it gets more re-posts 😇. We are looking for a research software engineer to help us develop (even) better code for #compchem #atomicscale #machinelearning. Check out the specs and apply! www.epfl.ch/labs/cosmo/i...
epfl.ch
Jobs
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