iiinova — where your digital self keeps evolving

Ultan McDermott @ultanmcd.bsky.social · 04/04/2025

This is pretty depressing - why OpenSNP, a company with a data-centric belief that genetic data would be a key driver for improving human health and medicine, will close (and delete all of its data) opensnp.wordpress.com. Turns out the biggest users were law enforcement and govt, not labs or pharma.

opensnp.wordpress.com

openSNP

crowdsourcing genome wide association studies

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Reposted by Ultan McDermott

George Takei @georgetakei.bsky.social · 30/03/2025

And yet Joe Rogan puts guests on who say "Vaccines aren't actually responsible for the reduction in infectious diseases.”

The image is a heatmap titled "Measles," showing measles cases across U.S. states from 1928 to 2003. States listed on the y-axis include Alaska, Arkansas, California, Connecticut, Delaware, Georgia, Iowa, Illinois, Kansas, Louisiana, Maryland, Michigan, Missouri, Montana, North Dakota, New Hampshire, New York, Oklahoma, Pennsylvania, South Carolina, Tennessee, Utah, Vermont, Wisconsin, and Wyoming. The x-axis spans years from 1928 to 2003. A vertical line marks the introduction of the measles vaccine around 1963. The color scale at the bottom ranges from blue (0 cases) to red (4,000+ cases), with shades of green, yellow, and orange indicating intermediate values (1,000, 2,000, 3,000 cases). Before 1963, many states show frequent high case numbers (yellow to red), while after 1963, cases drop significantly, with mostly blue indicating near-zero cases.

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Ultan McDermott @ultanmcd.bsky.social · 21/03/2025

Interesting discussion re NHS Galleri study using methylation of cfDNA in 140K volunteers randomised to Galleri vs standard of care - whether reduction in late stage III/IV versus cancer mortality are best endpoints www.genomeweb.com/cancer/debat...

genomeweb.com

Debate Over Multi-Cancer Screening Tests Shifts Pending Grail Randomized Trial Results

Leaders from diagnostics firms and academia discussed the challenges of assessing these tests and the need for a consensus on how to bring them to the clinic.

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Ultan McDermott @ultanmcd.bsky.social · 06/03/2025

Please forward to any interested scientists - we're looking for a scientist to work in our functional genomics centre to find new cancer targets in Cambridge, UK. A mix of wet lab as well as computational skills a plus. astrazeneca.wd3.myworkdayjobs.com/Careers/job/...

astrazeneca.wd3.myworkdayjobs.com

Senior scientist – functional genomics

Senior scientist – functional genomics Location: Cambridge Salary: Competitive About AstraZeneca AstraZeneca is a global, science-led, and patient-focused biopharmaceutical company that focuses on the...

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Ultan McDermott @ultanmcd.bsky.social · 06/12/2024

Hi - if any newly minted PhD students interested in a 1-year post in AstraZeneca in Cambridge, UK working on drug resistance - please share with your networks. An opportunity to see what it's like in industry. astrazeneca.wd3.myworkdayjobs.com/Careers/job/...

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Ultan McDermott @ultanmcd.bsky.social · 08/09/2024

Antibody drug conjugates are showing promise across a range of solid tumours and haem malignancies - if you're confused by DAR, linkers, payloads....this is a great starting place! www.nature.com/articles/d41...

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