Sign in

Mission Bio

@missionbio.bsky.social
69 followers 36 following 51 posts

The Tapestri® Platform; the only technology that provides single-cell targeted DNA sequencing at single-base resolution

PostsRepliesMedia
Mission Bio @missionbio.bsky.social · 22/09/2026
"Triomics allows us to move beyond identifying which cells carry a mutation and begin asking what that mutation means for their biology." — Dr. Terra L. Lasho, Mayo Clinic. Learn more: www.missionbio.com/capabilities...
missionbio.com
Tapestri Triomics: DNA, RNA & Protein in One Cell
Explore Tapestri Triomics, Mission Bio's single-cell platform measuring DNA, RNA, and protein from the same cell to reveal genotype-to-phenotype connections.
010
Mission Bio @missionbio.bsky.social · 31/08/2026
We're giving away $33,333 in Mission Bio products or services to one World Single-Cell Day registrant and attendee. The number is not random. Terms apply (see comment on post). watch.getcontrast.io/register/wor...
watch.getcontrast.io
World Single Cell Day
What to Expect Scientific sessions from leading voices in single-cell research Emerging applications in cancer, immunology, and cell therapy Insights in...
110
Mission Bio @missionbio.bsky.social · 21/08/2026
Single-Cell 101, Volume 2: The Essentials takes you beyond the basics, with new content on cell and gene therapy (CGT) and single-cell RNA analysis. Grab your copy 👉 www.missionbio.com/resources/eb...
missionbio.com
Single-Cell Sequencing Vol 2: The Essentials | Mission Bio
Discover the "Resolution Revolution" in oncology. Download the Single-Cell Sequencing Vol2 eBook to learn how single-cell DNA and multi-omics uncover hidden clonal architecture, identify therapy-resis...
010
Mission Bio @missionbio.bsky.social · 18/08/2026
[New Blog Post] Most MRD tests can tell you if residual disease is there. They can't tell you which clones survived, or why. Our new blog looks at how single-cell multiomics closes that gap in AML and beyond. www.missionbio.com/company/blog...
missionbio.com
The Hidden Truth About Measurable Residual Disease (MRD) | Mission Bio
Measurable residual disease (MRD) predicts relapse in AML and beyond. See how single-cell multiomics reveals which clones survive treatment, and why.
000
Mission Bio @missionbio.bsky.social · 12/08/2026
3 speakers already announced. Consider joining us as we celebrate World Single-Cell Day: worldsinglecellday.com
worldsinglecellday.com
World Single Cell Day | One Cell Changes Everything
010
Reposted by Mission Bio
Linde Miles @lindemileslab.bsky.social · 04/08/2026
That’s all we wrote……We are closing the books on #MYELOID2026!
111
Mission Bio @missionbio.bsky.social · 27/05/2026
[New Application Note] We collaborated with Integrated DNA Technologies (IDT) to highlight how Nechama Kalter & the Ayal Hendel lab are characterizing CRISPR edits in primary T cells. www.missionbio.com/resources/te...
missionbio.com
Multi-Scale Characterization of CRISPR Editing Outcomes Using rhAmpSeq™ and Tapestri® Single-Cell Multiomics | Mission Bio
Learn how pairing Integrated DNA Technologies’ (IDT) rhAmpSeq™ System and Mission Bio’s Tapestri® enables deep single-cell characterization of CRISPR genome editing in primary T cells
010
Mission Bio @missionbio.bsky.social · 30/04/2026
Our biggest discount on the Tapestri Single-Cell Instrument ever! Save over $50K. What you can do with Tapestri: Connect genetic variation to gene expression in the same cells Confirm gene editing outcomes Resolve clonal structure in complex samples & much more! www.missionbio.com/promo
missionbio.com
Save Over $50,000 on The Tapestri Single-Cell Insrument in May 2026
Bring the Tapestri Platform in-house this May for just $99,000. Unlock single-cell DNA, RNA, and protein resolution at our lowest price ever. Offer ends May 31.
011
Reposted by Mission Bio
The American Journal of Pathology @ajpathology.bsky.social · 25/04/2026
Single-Cell Triomics Analysis of Tumor Cells Infiltrating Patient-Derived Breast Cancer Scaffolds. Authors from @missionbio.bsky.social #OpenAccess text: ajp.amjpathol.org/article/S0002-944…
011
Mission Bio @missionbio.bsky.social · 24/04/2026
You probably don't know what you're doing already for the 16th of June....well, we do. We'll be hosting this fascinating webinar, sign up today: watch.getcontrast.io/register/mis...
watch.getcontrast.io
Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment
The use of CRISPR-Cas9 genome editing has been wildly successful in the cell & gene therapy space, but DNA double-strand breaks can trigger severe genotoxi...
011
Mission Bio @missionbio.bsky.social · 21/04/2026
Watch the full presentation, less than 20 mins, available at this link: watch.getcontrast.io/register/mis...
000
Mission Bio @missionbio.bsky.social · 15/04/2026
Watch the webinar on-demand here: www.the-scientist.com/high-through...
000
Mission Bio @missionbio.bsky.social · 14/04/2026
No forms, just science. Download our updated Tapestri® CGT Safety flyer. See how single-cell multiomics de-risks programs by mapping gene editing co-occurrence, VCN, and genotoxicity in every cell to meet FDA CMC standards.Get the PDF: www.missionbio.com/resources/br...
missionbio.com
Tapestri Platform Cell and Gene Therapy Solutions | Mission Bio
Download the Tapestri® Cell & Gene Therapy flyer to see how single-cell multiomics evaluates CQAs like vector copy number, gene editing co-occurrence, and genotoxicity to meet FDA CMC guidelines.
000
Mission Bio @missionbio.bsky.social · 02/04/2026
[Open Paper] Most evolutionary studies on pancreatic cancer rely on bulk sequencing, yet clonal evolution happens at the single-cell level. Read the paper here: www.nature.com/articles/s41...
nature.com
Genomic evolution of pancreatic cancer at single-cell resolution - Nature Genetics
This study uses single-cell DNA sequencing to analyze genomic evolution in pancreatic cancer using a cohort of multiregionally and longitudinally sampled patients’ tissues across various clinical cont...
000
Mission Bio @missionbio.bsky.social · 31/03/2026
www.the-scientist.com/high-through...
the-scientist.com
High-Throughput Single-Cell Assessment of Multiplex Gene Editing | The Scientist
In this webinar, Stefan Radtke will discuss the development of new high-throughput single-cell readouts for precise and comprehensive tracking of gene editing outcomes after autologous hematopoietic s...
010
Mission Bio @missionbio.bsky.social · 20/03/2026
[New Blog Post] Bulk NGS masks the truth in AML. Retrospective BLAST trial data shows that single-cell DNA+Protein reveals the CXCR4 biomarkers that actually predict patient response. Stop averaging. 🧬 www.missionbio.com/company/blog...
missionbio.com
Clinical Utility of Single-Cell CXCR4 Biomarker Stratification for Motixafortide Treated Acute Myeloid Leukemia Patients | Mission Bio
Discover how single-cell CXCR4 biomarker stratification revealed hidden clinical utility for Motixafortide in AML patients, overcoming the limitations of bulk sequencing.
000
Mission Bio @missionbio.bsky.social · 18/03/2026
Learn how Tapestri enables comprehensive single-cell sequencing of DNA, RNA, and proteins to study cancer, clonal mosaicism, and cell therapies with precision. 🔗 www.missionbio.com/company/blog...
missionbio.com
Single-Cell Sequencing: Targeted DNA + RNA Analysis With Tapestri | Mission Bio
Learn how Tapestri enables comprehensive single-cell sequencing of DNA, RNA, and proteins to study cancer, clonal mosaicism, and cell therapies with precision.
000
Reposted by Mission Bio
The American Journal of Pathology @ajpathology.bsky.social · 14/03/2026
#ArticleinPress: Single-Cell Triomics Analysis of Tumor Cells Infiltrating Patient-Derived Breast Cancer Scaffolds. Authors from @missionbio.bsky.social #OpenAccess text: ajp.amjpathol.org/article/S0002-944…
031
Mission Bio @missionbio.bsky.social · 02/03/2026
www.linkedin.com/posts/missio...
linkedin.com
[Happening This Week] This week Daniele Canarutto, M.D., Ph.D. will present how single-cell DNA sequencing was used to rigorously validate genomic editing outcomes for their CRISPR-based therapy… | Mi...
[Happening This Week] This week Daniele Canarutto, M.D., Ph.D. will present how single-cell DNA sequencing was used to rigorously validate genomic editing outcomes for their CRISPR-based therapy targe...
000
Mission Bio @missionbio.bsky.social · 26/02/2026
[Register Today] Hyper-IgM 1 (HIGM1) is an X-linked combined immunodeficiency caused by CD40LG mutations that impair communication between activated CD4⁺ T cells and effector immune cells, resulting in a markedly reduced life expectancy. Register here 👉 watch.getcontrast.io/register/mis...
watch.getcontrast.io
Single-cell DNA sequencing provides a comprehensive assessment of genomic editing outcomes of gene-corrected CD4 T-cells for treating Hyper IgM1 supporting the start of clinical trial
Hyper-IgM 1 (HIGM1) is an X-linked combined immunodeficiency that is caused by a CD40LG mutation that impairs communication between active CD4+ T cells and...
010
Mission Bio @missionbio.bsky.social · 18/02/2026
www.linkedin.com/posts/missio...
linkedin.com
Single-Cell Sequencing: Targeted DNA + RNA Analysis. | Mission Bio
From genotype to phenotype at single-cell resolution. See how targeted DNA + RNA analysis helps researchers connect variants to cellular function and uncover new biological insight.
000
Mission Bio @missionbio.bsky.social · 13/02/2026
Less than 30 minutes of your time. Register today for our premiere on February 20th of our on demand webinar titled "Biomarkers in the ERA of precision medicine" Register here: watch.getcontrast.io/register/mis...
White background. Mission Bio logo is present top left. Red text reading "Exclusive Webinar Premiere" Black text follows reading "Biomarkers in the ERA of precision medicine." A red button is present at the bottom that has white text reading "Register Today" A scientific image depicting cells is present on the right hand side.
000
Mission Bio @missionbio.bsky.social · 29/01/2026
[Live Webinar] Join our upcoming webinar to see how single-cell proteogenomic analysis of PDX models reveals clonal evolution, resistance mechanisms, and drug interactions under therapeutic pressure. Secure your spot: watch.getcontrast.io/register/mis...
watch.getcontrast.io
Single-cell proteogenomic analysis of clonal evolution in PDX models of AML treated with IDH inhibitors
Clonal heterogeneity in acute myeloid leukemia (AML) can drive drug resistance because different clones may respond variably to treatments. Studying the ev...
000
Mission Bio @missionbio.bsky.social · 15/01/2026
Join us at hashtag#FOG2026 Find out how you can directly link genotype to phenotype & unravel the threads of multiomics from the same single-cells. 📍 Visit Booth 117 💡 Seminar Day 1, 2.40 PM, Multiomics Stage 📩 Message us to arrange a meeting The Mission Bio team look forward to meeting you!
Mission Bio logo is present top left, and the festival genomics is in the top right. The background I should add is white. Large font, in black, reads "Directly link genotype to phenotype with single-cell multiomics" this is followed by red text that reads "Join us at booth 117 to find out how." Smaller text in blue covers the date, which is January 28-29, 2026 and the location, which is London, England.
010
Mission Bio @missionbio.bsky.social · 09/12/2025
[Secure Your Spot] Register today for Single-cell profiling of genome-editing alterations and functional outcomes in CRISPR-engineered cells. Whether you can make it live, or not, register to gain access. watch.getcontrast.io/register/mis...
watch.getcontrast.io
Single-cell profiling of genome-editing alterations and functional outcomes in CRISPR-engineered cells
To overcome the limitations of bulk analysis in genome editing in applications like therapeutics, which can mask critical off-target events that compromise...
000
Mission Bio @missionbio.bsky.social · 05/12/2025
Attending #ASH2025? Bring any curiosity you might have about the world of Single-cell to booth 2129. You can snag an appt at this link if you prefer to manage your time - go.missionbio.com/ASH2025
White image background with Mission Bio Logo alongside the logo for ASH (American Society for Hematology. Text reads "Meet with us at ASH! (in black) and red text follows reading "Bring Your Single-cell questions, and meet with our team." Blue text at the bottom reads December 6-9 2025. Booth 2129, Orlando, FL"
000
Mission Bio @missionbio.bsky.social · 20/11/2025
[Press Release] “The DNA+RNA assay provides powerful resolution into the mutational landscape and cell states within leukemia,” says Bobby Bowman, PhD, Assistant Professor. Read the full release here: missionbio.com/press/target...
missionbio.com
Mission Bio Announces Single-Cell Targeted DNA + RNA Assay at ASH 2025, Closing the Mutation-to-Expression Gap in Cancer Research | Mission Bio
Mission Bio launches the Tapestri DNA + RNA Assay, the first single-cell platform to link mutations with gene expression, advancing precision medicine and therapy development.
000
Mission Bio @missionbio.bsky.social · 11/11/2025
Discover our webinars right here: watch.getcontrast.io/missionbio
000
Mission Bio @missionbio.bsky.social · 10/11/2025
[blog post] Adapting Tapestri for Single-Cell RNA-Seq: Customer Stories. missionbio.com/company/blog...
Image features a RNA with cells. Text reads "Single-cell applications" "Adapting Tapestri for Single-Cell RNA-Seq: Customer Stories. A red button reads "Read the blog"
000
Mission Bio @missionbio.bsky.social · 07/11/2025
[Upcoming Webinar] See how single-cell DNA + DNA methylation + surface protein profiling with scTAM-seq (on Tapestri) dissects treatment response in MDS/AML using sequential patient bone-marrow samples collected during targeted therapy. watch.getcontrast.io/register/mis...
Black image, with inlayed image of cells. Mission Bio logo is present, a read button saying "Register Now" is also there. The title of the webinar reads "Deconvolution of clonal dynamics with scTAM-seq"
000
Mission Bio @missionbio.bsky.social · 06/11/2025
Happy Peppermint Mocha Day to everyone celebrating! Yes, it's true, like the Pumpkin Spice Latte, it pairs wonderfully with our Single-cell Sequencing 101 eBook! 🔗 - missionbio.com/resources/eb...
Image, black background, and ipad screen. Mission Bio logo top left. Red call-to-action buttion reading "Get the Ebook." Main text reads single-cell sequencing 101.
000
Mission Bio @missionbio.bsky.social · 03/09/2025
To overcome cellular heterogeneity, the critical challenge driving drug resistance in oncology and impacting safety in cell & gene therapy, targeted single-cell DNA and RNA analysis is the key to linking genetic drivers to their functional expression in every cell. missionbio.com/company/blog...
missionbio.com
Pharma Assay Development with Single-Cell Targeted DNA + RNA Analysis. | Mission Bio
De-risk drug development and cell & gene therapies with targeted single-cell multi-omics linking genomics with gene expression data leveraging Mission Bio’s Pharma Assay Development (PAD) services.
010
Mission Bio @missionbio.bsky.social · 25/08/2025
[Open Paper] Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing. bmccancer.biomedcentral.com/articles/10....
bmccancer.biomedcentral.com
Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing - BMC Cancer
Background Cutaneous squamous cell carcinoma (CSCC) is a prevalent skin cancer with aggressive progression that poses significant challenges, especially in metastatic cases. Single-cell DNA sequencing...
000
Mission Bio @missionbio.bsky.social · 21/08/2025
www.youtube.com/shorts/e9nYe...
youtube.com
What is Single-Cell Multiomics?
YouTube video by Mission Bio
000
Mission Bio @missionbio.bsky.social · 19/08/2025
In this blog post, discover how single-cell multi-omics helps you see what bulk methods miss. By linking DNA, RNA, and protein in the same cell, researchers can spot relapse earlier, follow clonal evolution, & shape better therapies for cancer and cell & gene therapy. missionbio.com/company/blog...
An image, where the background image is a DNA protein. The image reads "What is single-cell multi-omits?" which is the title of the blog the post is linked to.
000
Mission Bio @missionbio.bsky.social · 06/08/2025
🚨 [New Blog] 🚨 Discover how by combining single-cell targeted DNA and RNA analysis, Mission Bio’s Tapestri platform now lets researchers connect genotype with function for a more complete view of disease biology. 🖊️ - Authored by Jacqueline Marin Read here: missionbio.com/company/blog...
010
Mission Bio @missionbio.bsky.social · 05/08/2025
📣 [New Press Release] - Mission Bio is accelerating the development of single-cell tri-omics to unlock deeper insights in cancer research and treatment. Read the full release here: missionbio.com/press/equity...
Mission Bio Secures Equity Financing to Accelerate Single-Cell Trio-mics Platform Expansion. Image of Mission Bio Tapestri Instrument.
010
Mission Bio @missionbio.bsky.social · 18/06/2025
Last call for savings! 📣 Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data. Learn more 👉 bit.ly/453RcBr
000
Mission Bio @missionbio.bsky.social · 05/06/2025
We're excited to announce our newest advancement in precision oncology: the Single-Cell Genotype and Targeted Gene Expression assay! This solution enables simultaneous profiling of genotype and targeted gene expression in over 10,000 cells 🎉 Learn more ➡️ bit.ly/4ktWgUE
010
Mission Bio @missionbio.bsky.social · 04/06/2025
💸Budget tight? We’ve got your back. Mission Bio is offering limited-time discounts on Tapestri® kits and warranties to help academic and non-profit labs stretch their budgets further — and still generate high-impact single-cell data. Learn more 👉 bit.ly/453RcBr
000
Mission Bio @missionbio.bsky.social · 21/05/2025
Published today in @nature.com, researchers from @crg.eu and @irbbarcelona.org utilized Tapestri to develop EPI-clone, which tracks clonal dynamics in hematopoiesis with naturally occurring DNA methylation patterns. Learn more here ➡️ bit.ly/4drZc12
bit.ly
Nature Publication Shows Mission Bio's Tapestri® Platform Enables Real-Time, Single-Cell Tracking of Precancerous Clones Using Natural Epigenetic Markers | Mission Bio
Epigenetic barcoding incorporating Tapestri unlocks high-throughput single-cell lineage tracing of clonality with or without mutation drivers, a previously invisible precursor to cancer development EP...
032
Mission Bio @missionbio.bsky.social · 14/05/2025
#ASGCT2025 is in full swing! We're having a blast in New Orleans meeting everyone and sharing how Tapestri is advancing genome editing validation with single-cell precision. Swing by Booth #1749 to say hello to our team! 👋
000
Mission Bio @missionbio.bsky.social · 13/05/2025
At #ASGCT2025? Don’t miss our poster on advancing genome editing validation with single-cell precision 🧬 Comprehensive On- and Off-target Validation Using Integrated rhAmpSeq and Targeted DNA Resequencing Single-Cell Technology 📅 May 15 | 5:30 PM CT Learn more here ➡️ bit.ly/4jS33Hc
000
Mission Bio @missionbio.bsky.social · 08/05/2025
🎉 We're headed to the Big Easy! Join us next week in New Orleans for @asgct.bsky.social #ASGCT2025 🎉 Visit Mission Bio at Booth #1749 to learn more about how Tapestri is advancing #cgt characterization 🧬 Check out the *can't-miss* oral and poster presentations here ➡️ bit.ly/3SrruPD
000
Mission Bio @missionbio.bsky.social · 06/05/2025
Our partnership with Integrated DNA Technologies is built on the principle of therapeutic safety— bringing single-cell resolution and unmatched precision to genome editing analysis. Read the full story here 👉 bit.ly/3GBbCro
000
Mission Bio @missionbio.bsky.social · 17/04/2025
Bulk sequencing and traditional assays miss critical details that impact the safety and efficacy of cell therapies. 🧐 With the Tapestri, you can interrogate zygosity, detect off-target effects, and assess immunophenotype—all in one assay. Learn more ➡️ bit.ly/42kjBS5
000
Mission Bio @missionbio.bsky.social · 16/04/2025
Our team is having an *AWSOM* time in Atlanta today at the 4th annual Atlanta Workshop of Single-cell Omics. If you're attending, be sure to swing by our table to say hi! 👋 Learn more about the Tapestri platform here ➡️ missionbio.com/products/pla...
000
Mission Bio @missionbio.bsky.social · 10/04/2025
Actionable Insights, Accelerated Outcomes 💪 Get the right drug to market faster with PAD services. Learn more about PAD services for drug development here ➡️ bit.ly/4ia8uj2
010
Mission Bio @missionbio.bsky.social · 01/04/2025
Your partner at every step 🤝 From assay design to sample analysis and data interpretation, the PAD Services Team is here to help. Learn more ➡️ bit.ly/3FLtsYj
010
Mission Bio @missionbio.bsky.social · 26/02/2025
🚨 Last chance to register!🚨 Join us tomorrow to learn how researchers from @cincychildrens.bsky.social utilized single-cell DNA + Fusion multi-omic analysis for acute leukemias 📅 Thursday, February 27 ⏰ 11:30a ET | 8:30a PT Register here ➡️ bit.ly/4131uPD
000