iiinova — where your digital self keeps evolving

Miranda Evans @mirandaevans.bsky.social · 02/04/2026

Thank you for an amazing UK Archaeological Science Conference @ogu-bristol.bsky.social! I was delighted to be awarded 2nd prize for my presentation "Optimising Protease Strategies for Detecting Ancient Viral Proteins" 🧪 #palaeoproteomics Can't wait for next time!

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Miranda Evans @mirandaevans.bsky.social · 02/03/2026

🚨Open Access paper out today in Praehistorische Zeitschrift! "A first toast in Kuyavia: New evidence for drinking rituals in Neolithic Europe from Sławęcinek, Poland" Led by Łukasz Kowalski www.degruyterbrill.com/document/doi...

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

5/5 🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs. 📄 Paper: doi.org/10.1371/jour... 💻 GitHub: github.com/miranda-e/De...

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

4/5 📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

3/5 💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

2/5🧵 🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

1/5🧵 🚨 New open access paper out today🚨 The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics. doi.org/10.1371/jour... #palaeoproteomics

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Miranda Evans @mirandaevans.bsky.social · 13/01/2026

2/5 🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.

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Miranda Evans @mirandaevans.bsky.social · 14/10/2025

Please join us online or in person for this term's Garrod Seminar Series 'Consumed by time: Past foodways in practice' @cam-archaeology.bsky.social. We are delighted to have an amazing line up of experts in their field speaking. More details here: talks.cam.ac.uk/show/index/1...

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Miranda Evans @mirandaevans.bsky.social · 20/09/2025

Thank you! I love making posters. The skull is a flap, which reveals CT scans when raised.

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Miranda Evans @mirandaevans.bsky.social · 20/09/2025

Having a blast at BABAO! @babao2025meeting.bsky.social Thanks everyone who came and saw our poster "The Curious case of the Candia skull: demography revealed by minimally invasive methods" @drtrishbiers.bsky.social

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Miranda Evans @mirandaevans.bsky.social · 15/09/2025

Delighted to report that my manuscript "The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics" has been recommended by PCI. The Demodifier, an open source tool, screens for inaccurate taxonomic matches caused by PTMs www.biorxiv.org/content/10.1...

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Miranda Evans @mirandaevans.bsky.social · 10/09/2025

Thank you @isba11.bsky.social for a fantastic conference!!! I can't wait to find out where the next one is. And thank you to everyone who came to my talk "The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in ancient protein studies".

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Miranda Evans @mirandaevans.bsky.social · 09/02/2024

Apparently I talk with my hands. Thanks for having me to present on "The Proteomics of Pottery: what can dirty dishes tell us about ancient diet and cuisine?" at the Pudding Seminar, @Newnham_College!

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