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Milton Pividori @miltondp.bsky.social · 19/03/2026

CCC-GPU reveals patterns that standard correlations miss, including relationships present only in subsets of samples, such as sex-specific gene expression effects. 4/n

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Milton Pividori @miltondp.bsky.social · 19/03/2026

The original CCC was powerful but computationally expensive. CCC-GPU changes that: ⚡ ~37× speedup in GTEx-scale data ⚡ Whole multi-tissue analysis in hours instead of ~2 weeks This makes large-scale nonlinear correlation analysis practical. 3/n

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Milton Pividori @miltondp.bsky.social · 19/03/2026

Popular correlation methods focus on linear or monotonic patterns. CCC is different: → It uses clustering → Captures linear + nonlinear relationships → Works with mixed data types (you can correlate with metadata, if available) 2/n

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Milton Pividori @miltondp.bsky.social · 19/03/2026

Our CCC-GPU paper is published in Bioinformatics (Oxford)! 🚀 CCC is a not-only-linear correlation coefficient that uncovers complex gene-gene relationships beyond linear patterns. Now it runs on GPUs! doi.org/10.1093/bioi... Huge credit to @haoyu-zc.bsky.social! 1/n

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Reposted by Milton Pividori

CU Department of Biomedical Informatics @cubiomedinfo.bsky.social · 04/03/2026

Using a familiar correlational coefficient like Spearman’s or Pearson’s on molecular data may miss some complex patterns that exist. To overcome this, researchers at @cuanschutz.bsky.social including @miltondp.bsky.social developed CCC—a new statistical framework ➡️ cudbmi.info/ccc-1

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Milton Pividori @miltondp.bsky.social · 27/06/2025

With software engineers from @cubiomedinfo.bsky.social, we developed Manugen-AI, an agentic AI system to automate the mechanical tasks of writing a scientific article #adkhackathon Check it out! Devpost: devpost.com/software/aca... Code: github.com/pivlab/manug... Medium: medium.com/@miltondp/ma...

devpost.com

Academic Manuscript Generation from Assets and Guidance

Writing academic manuscripts can be tedious. Imagine that you could bring together your results, prior research, and some brief bullet points per section to generate a manuscript automatically.

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