Analysing generalized anxiety symptoms as a quantitative trait rather than a clinical diagnosis, Skelton, Mitchell and colleagues report a genome-wide meta-analysis of 693,869 individuals identifying ...

Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism...

Background Alzheimer’s dementia (AD) is a leading cause of disability and dependency in older adults. Frailty is a phenotypic risk factor for AD, but its causal role remains unclear - partly due to re...

Nature - A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of...