Neuron is one of the most influential and relied upon journals in the field of neuroscience and serves as a premier intellectual forum for the entire neuroscience community.

We provide some guidance and examples to clear up common misconceptions about special relativity. These misconceptions often come from trying to express the truths of special relativity in Newtonian t...

A neurotransmitter known to quiet activity in the brain can sometimes do the opposite, researchers find, offering implications for psychiatric treatment.

Chiu et al. found that activation of SST-expressing interneurons induces tonic currents through dendritic α5-containing GABA receptors in pyramidal neurons of the neocortex. Tonic GABAergic hyperpolarization deinactivates dendritic voltage-gated calcium channels, enhancing calcium influx during action potentials. Increased dendritic calcium signaling facilitates calcium- and endocannabinoid-dependent inhibitory synaptic plasticity.

Brain activity is highly regulated by GABAergic activity, which can suppress neuronal excitability and synaptic integration. Tonic GABAergic conductan…

Bridging molecular, cellular, and systems neuroscience. We study neural circuits from synaptic boutons to cortical networks in behaving animals.

Using dual-color mesoscopic imaging in the neocortex of awake mice, the authors show that cholinergic release and neuronal activity exhibit distinct spatiotemporal patterns that are differentially lin...

Neuromodulation by acetylcholine (ACh) plays a critical role in reshaping neural dynamics in the neocortex as a function of development, behavioral state, and learning [1][1]–[6][2]. Prior work sugges...