Reposted by Max Marin
I’m excited to share our new preprint introducing HipHap, a tool for assigning long reads to haplotype-resolved diploid reference assemblies!
With Max Marin, Matthew Meyerson, and @lh3lh3.bsky.social
Preprint: www.biorxiv.org/content/10.6...
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biorxiv.org
HipHap: Haplotype Assignment and Confidence Scoring for Diploid Reference Genomes
Diploid genome assemblies are now routinely available, but most read aligners were designed for haploid references, which have long been the gold standard. When reads are aligned to a diploid assembly...
