Reposted by Monica Fernandez Quintero
Happy to share the first research article from my lab, now open access at Nature Communications! We report a single mutation (T199I) outside of the H5 receptor binding site (RBS) dramatically increases RBS flexibility and allows for broader binding to its receptor.
www.nature.com/articles/s41...
nature.com
A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth - Nature Communications
Highly pathogenic avian influenza clade 2.3.4.4b H5N1 viruses are causing a multistate outbreak in dairy cows. In this study, the authors report that recent H5N1 viruses have acquired a single mutatio...
