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Metabo_Dave

@metabodave.bsky.social
1.2K followers 907 following 1.5K posts

Mourning the days when all we talked about was font choice, reference styles and glam humping.

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Reposted by Metabo_Dave
Drug Monkey @drugmonkey.bsky.social · 08/09/2026
And there it is. As rumored, and as predicted by YHN from the gitgo, enhanced triage of NIH grants will continue. grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-114: Continuation of Modifications to Peer Review Practices
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Continuation of Modifications to Peer Review Practices NOT-OD-26-114. NIH
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Jeremy Berg @jeremymberg.bsky.social · 07/09/2026
The estimated ~$700M potentially going to DOD/W could fully fund ~300 New Innovator Awards. 4/4
static.klipy.com
Stan Marsh: He Doesn't Care (South Park)
ALT: Stan Marsh: He Doesn't Care (South Park)
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Drug Monkey @drugmonkey.bsky.social · 04/09/2026
The National Institutes of Health, the premier funder of biomedical research in the world, insisted most research should include female subjects. Circa 2016.
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Metabo_Dave @metabodave.bsky.social · 25/08/2026
I have. In McDonalds in Holland
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Metabo_Dave @metabodave.bsky.social · 25/08/2026
static.klipy.com
The Office: Michael Scott's 'I Can't Do This'
ALT: The Office: Michael Scott's 'I Can't Do This'
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Metabo_Dave @metabodave.bsky.social · 25/08/2026
Hahahaha WUT????
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Reposted by Metabo_Dave
Grant Witness @grantwitness.org · 24/08/2026
Hello all! Grant Witness has a new website at grantwitness.org, and you can now subscribe to our newsletter and follow us at @grantwitness.org, or on whatever social feed you prefer (find them at linktr.ee/grantwitness)
grantwitness.org
Grant Witness
An independent, up-to-date, grant-level record of federal science funding disruptions in the United States.
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Drug Monkey @drugmonkey.bsky.social · 18/08/2026
NIH RFI on plans to stop using percentiles to select grants for funding drugmonkey.wordpress.com/2026/08/18/n...
drugmonkey.wordpress.com
NIH RFI on plans to stop using percentiles to select grants for funding
The NIH issued NOT-OD-26-088 Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review on 8/14/2026. It proposes a radical upheaval of the way that NIH’s Pr…
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Metabo_Dave @metabodave.bsky.social · 15/08/2026
Isn't it already like this, even without this change? Nobody knows what a findable score is now, so whilst I absolutely hate this change, it's just another nail in the coffin.
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Metabo_Dave @metabodave.bsky.social · 15/08/2026
This is an annoying one, and I think connected to the false belief from many in the NIH that all human studies are giant "clinical trials". Human studies come in many flavors, and small interventional/mechanistic experiments can easily be done with a K award in places with the right infrastructure.
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Metabo_Dave @metabodave.bsky.social · 10/08/2026
I think I've written a book chapter once (regrettably). Does that count?
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Kate Clancy @kateclancy.bsky.social · 03/07/2026
Read the whole article - but also bring it to your departments, your unions, your senate committees.
chronicle.com
Opinion | The Faculty Workload Myth
Politicians think faculty members don’t teach enough. Here’s what the data says.
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Drug Monkey @drugmonkey.bsky.social · 31/07/2026
This is reducing administrative burden? What is this, the fourth version of the DMS?
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Metabo_Dave @metabodave.bsky.social · 24/07/2026
"Unlike most presidential science advisers, Mr. Kratsios is not a scientist. He has a background in Silicon Valley, where he worked at an investment fund run by Peter Thiel.." I mean, what in the absolute fuck are we doing here?
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Metabo_Dave @metabodave.bsky.social · 22/07/2026
We can often mitigate these, but not perfectly and not without creating other issues (I.e. we can use more virus in females, but then what about toxicity?). Point is: I never know how far to go with it, particularly now where $$$ is incredibly tight. It's not simple.
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Metabo_Dave @metabodave.bsky.social · 22/07/2026
It seems like every experiment we do in males and females generates different findings, some major, some minor. The "problem" is there are often technical reasons, i.e. virus infection rates are different between sexes, which complicates interpretation of KO/OE studies when using viral delivery.
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Metabo_Dave @metabodave.bsky.social · 22/07/2026
"The researchers’ legal team is now asking the judge in the case to skip a trial and formally declare that the White House repeatedly violated the constitution, including the First Amendment. A court hearing on whether that’ll happen is scheduled for Oct. 20." Any openings before October 20th? 🙄
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Metabo_Dave @metabodave.bsky.social · 21/07/2026
The 7 year term only applies to certain UT schools (I.e. MD Anderson and some Health Science Centers). This is explicitly prohibited at other UT schools.
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Metabo_Dave @metabodave.bsky.social · 21/07/2026
"...including a 10-year, $2.5 million per year grant from the Wu Tsai Human Performance Alliance for a project he led" 😲😲😲
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Metabo_Dave @metabodave.bsky.social · 01/07/2026
Put. All. The. Arsenal. Players. On.
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Metabo_Dave @metabodave.bsky.social · 30/06/2026
Wait, I thought Amgen scientists were the ones concerned about rigor of the academic literature? 🤔 Medical journal retracts paper on Amgen’s Tavneos drug trial after FDA findings | Reuters share.google/O119v7aPjBH5...
share.google
Medical journal retracts paper on Amgen’s Tavneos drug trial after FDA findings
The New England Journal of Medicine on Monday retracted an article on a pivotal clinical trial that supported ​approval of Amgen’s rare-disease drug, citing concerns that patient outcome data ‌were al...
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Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 25/06/2026
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Jeff Lewis @lewislab.bsky.social · 15/06/2026
Had all 4 PhD students graduate in the last year. Found a soft landing for a tech that’s been in the lab for 5 years. Down to one half time staff scientist and 2 undergrads. Will rehire if one of my pending grants hits, and will operate with a skeleton crew if not.
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Julian Meeks @meeksandmilds.bsky.social · 15/06/2026
We are also fortunate to have an active R01, but natural movings-on (promotion, grad., end-of-window, etc.) will have us down 3/8 by end of summer. R01 with second-best R01 IS of my career sitting on the weak side of limbo. Right now we can't replace value/production on good projects. It sucks.
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Jason Rasgon @vectorgen.bsky.social · 15/06/2026
Just got an R01 and an R21, but I have several folk who already left and a couple others I managed to maintain for a bit on a combo of bridge and (very) limited endowment funds, so we'll likely be stable
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Metabo_Dave @metabodave.bsky.social · 15/06/2026
We are facing the inevitable reduction in force in my lab in the new year. I'm lucky that I've managed to get a new R01, but getting historically fundable scores on other apps (but no funding given paylines) won't be enough. How is everyone else doing right now? How many people are we losing?
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Drug Monkey @drugmonkey.bsky.social · 09/06/2026
NIH seeks input on capping grant awards drugmonkey.wordpress.com/2026/06/09/n...
drugmonkey.wordpress.com
NIH seeks input on capping grant awards
The NIH has posted a request for input on a proposal to limit the number of grant awards a given PI may hold at any one time. NOT-OD-26-086 Request for Information: Proposal to Cap the Number of Si…
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Metabo_Dave @metabodave.bsky.social · 09/06/2026
And this is just the start.
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I-75 Scientist @flscitriguy.bsky.social · 08/06/2026
RFI: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity and Innovation grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-26-086: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity a...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator ...
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Metabo_Dave @metabodave.bsky.social · 05/06/2026
If Cell Signaling Technology doesn't have the antibody you want, proceed with caution.
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Metabo_Dave @metabodave.bsky.social · 05/06/2026
The good old days. Nice to see Thermo keeping that spirit alive.
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Metabo_Dave @metabodave.bsky.social · 05/06/2026
Santa Cruz told me once that they would "move a band" on a datasheet after I pointed out the band in their image was the wrong size.
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Metabo_Dave @metabodave.bsky.social · 05/06/2026
The good thing about the Thermo Fisher scandal is that there is such a vibrant industry full of independent suppliers that are just primed and ready to do business with us.
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Colette Delawalla, PhD @cdelawalla.bsky.social · 05/06/2026
Members of the American Diabetes Association (ADA) were removed by police during the organization's annual meeting on Friday as they handed out copies of an editorial criticizing Trump administration changes to U.S. biomedical research. www.medpagetoday.com/special-repo...
medpagetoday.com
Video: Police Tussle With Diabetes Experts at ADA Meeting
Researchers told they could no longer attend the annual scientific sessions
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Metabo_Dave @metabodave.bsky.social · 05/06/2026
I mean, nobody is surprised by this.....right????
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Jonathan Howard @joho.bsky.social · 27/05/2026
"Uncertain federal funding means that next year, MIT may have about 500 fewer graduate students helping us to push the scientific frontier and preparing to contribute to society as scientists, inventors, designers, and entrepreneurs."
statnews.com
MIT president: Why so many optimistic scientists are losing heart
“This erosion of our strength is a loss for the nation,” writes MIT President Sally Kornbluth.
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Metabo_Dave @metabodave.bsky.social · 21/05/2026
I heard that the the NIA is only moving grants forward with scores of 2%ile or less. I hope that's not true.
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Metabo_Dave @metabodave.bsky.social · 04/05/2026
HR departments at universities just confuse the hell out of me.
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Metabo_Dave @metabodave.bsky.social · 04/05/2026
Surely we are at the bottom???
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Metabo_Dave @metabodave.bsky.social · 04/05/2026
It was last year when MYF kicked in around June or July I believe. Remember?
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Metabo_Dave @metabodave.bsky.social · 04/05/2026
....or the payline suddenly got cut in half.
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Jeremy Berg @jeremymberg.bsky.social · 30/04/2026
3/3
A bar graph showing that the chances of having a grant scoring within the top 10th percentile were 0.56 in fiscal year 2025 compared to ~0.9 for previous years.
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Metabo_Dave @metabodave.bsky.social · 04/05/2026
As we have learned recently, if it flips back to "council review completed" from "pending", you are well and truly effed
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Philipp Markolin @philippmarkolin.eurosky.social · 01/05/2026
New deep dive from me into the anti-science movement, it's structure, tactics, and impact on science and society. Some data analysis, unique testimonies, new infographics and also a first attempt at outlining broadly-agreed upon actions how to fight back. 1/ open.substack.com/pub/protagon...
open.substack.com
We need to talk about the anti-science movement
6 lessons scientists under siege learned the hard way, and how we all can fight back
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Rep. Mike Levin @levin.house.gov · 03/05/2026
Project 2025 called for gutting the EPA's scientific research office. In under a year, the Trump Administration has done exactly that, taking a division of more than 1,500 scientists down to 124…
nytimes.com
How the Trump Administration Ended Independent Science at the E.P.A.
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Drug Monkey @drugmonkey.bsky.social · 18/03/2026
Bhattacharya Appropriation Oversight Hearing drugmonkey.wordpress.com/2026/03/17/b...
drugmonkey.wordpress.com
Bhattacharya Appropriation Oversight Hearing
NIH testifying to Congress on 03/17/2026 [YouTube Link] 20:18 – lauding NIH funded research for the latest highly promising HIV medications which have the potential for an eradication success…
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Metabo_Dave @metabodave.bsky.social · 18/03/2026
Thanks Biden
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Metabo_Dave @metabodave.bsky.social · 18/03/2026
Yes
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Metabo_Dave @metabodave.bsky.social · 18/03/2026
Yeh but he gave me a free cell phone, so he's off the hook.
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Metabo_Dave @metabodave.bsky.social · 18/03/2026
Thanks Biden
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