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Alex Merz 🇺🇸🇨🇦🇺🇦

@merz.bsky.social
6.2K followers 4.3K following 35K posts

"There are no answers; only choices" – S. Lem Professor of Biochemistry, UW Seattle Bacteria, yeast, membranes, SNAREs, type IV pili, dissonant music, bikes Any coincidence of my opinions with my employer's is coincidental

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 34m
I was prob. too vague.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 36m
I was talking about nations going to war with Iran in the modern era.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 40m
Vietnam went to war with Iran?
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 41m
I'd argue that there were strategic frameworks for the first two, and that the failures occurred because the frameworks were flawed (and became more flawed over time), not because they did not exist at all.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 48m
IRAQ has entered the chat
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 48m
It's pretty easy to lose a war no matter who you are, if there is no underlying coherent strategic framework whatsoever.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 50m
I don't think he believes in anything at all. What he is is a bullshitter, in Frankfurt's sense.
press.princeton.edu
On Bullshit
Over one million copies sold worldwideThe international and #1 New York Times bestsellerThe anniversary edition of the acclaimed book that reveals why bullshit is more dangerous than lying
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
Reposting that essay whenever Brooks is mentioned is one of my little missions in life.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
It is a paradox: he is an intellectual vacuum yet he can vent rhetorical flatulence.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
Is this what you had in mind when you voted to confirm Bessent, @cantwell.senate.gov? Please explain. As a constituent I am still baffled by your decision and nothing that you or your beleaguered staffers have said provides any meaningful explanation. You owe it to your constituents to explain.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
They've had him on regularly for like 20 years. Total institutional failure.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
As I've been saying lately, I used to believe that there is too much imposter syndrome in the world. I now believe that there is not remotely enough of it.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
No AI and no AI-directed wetlab that is anticipated in the reasonably foreseeable future can do the kind of exploratory membrane reconstitution biochemistrymy lab is doing. My colleagues may or may not think we're asking the most important questions but they are questions that AI *cannot* answer.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
Brooks has always been entirely full of shit.
phillymag.com
David Brooks: Boo-Boos in Paradise
The classic 2004 examination of David Brooks’s “Bobos in Paradise” by Philadelphia magazine’s Sasha Issenberg.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 1h
A reminder about Jamelle's charlatan colleague at the NYT: Brooks knows nothing and believes nothing.
phillymag.com
David Brooks: Boo-Boos in Paradise
The classic 2004 examination of David Brooks’s “Bobos in Paradise” by Philadelphia magazine’s Sasha Issenberg.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 3h
The extent to which I have seen good scientists diminished by bad money is just… really depressing.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 3h
#NotAllMolecularGerontology, of course. Just ~98% of it.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 3h
That pretty much encapsulates my feelings about the field of molecular gerontology.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 3h
I saw the best minds of my generation destroyed by madness, starving hysterical naked, dragging themselves through the negro streets at dawn looking for an angry fix, angelheaded hipsters burning for the ancient heavenly connection to the starry dynamo in the machinery of night -Alan Ginsburg
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Reposted by Alex Merz 🇺🇸🇨🇦🇺🇦
Ruha Benjamin @ruha9.bsky.social · 5h
“Texas Tech’s censorship policy does not just affect the humanities. According to the AAUP lawsuit, medical students at the campus in El Paso are no longer permitted to learn about racial disparities in medical care or how to treat underserved populations.” www.theatlantic.com/ideas/2026/1...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 3h
Here's what these bastards think about our National Parks.
npca.org
FAQ: Border Destruction at Big Bend
The Trump administration destroyed parts of Big Bend National Park in August. We answer frequently asked questions and share how you can help.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 4h
hate it
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 4h
"Electronegatively,"
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 4h
@cantwell.senate.gov, I'm still trying to understand why you voted to confirm Bessent. Is this what you had in mind? Asking as a baffled constituent.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 16h
It is particularly telling (but again, not surprising) that you invoke Tuskegee as a comparator, and then do not address its well established historical consequences.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 16h
Before reading this I would have predicted that you would not address predictable adverse effects of the trial on community trust and subsequent interaction with the health care system. That prediction was, unsurprisingly, correct. I did not expect much of you and was not disappointed.
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Reposted by Alex Merz 🇺🇸🇨🇦🇺🇦
United Farm Workers @ufw.bsky.social · 18h
Warrantless stops and violent roving patrols by masked federal agents across California, especially the Central Valley, have been terrorizing farm workers for the past 5 days. The chaos is escalating. full statement: www.dailykos.com/stories/2026...
United Farm Workers union condemns brutal
ICE surge impacting farm workers in Central Valley; highlights Rep. Valadao's comments as 'insulting' to his constituents
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
Interesting model.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
There may well be but they aren’t showing themselves yet.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
I did not say I was certain. Insaid that was my bet. Reading is fundamental.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
Hilarity ensues.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
This is a T-shirt that I own.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 17h
Note that the decline is linear meaning that the likelihood that a given Trump approver will flip is *increasing* over time. This is the opposite of what we’d expect to see with a hard floor of support.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
WSJ Op-Ed page was like that even before Murdoch bought the paper.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
Also just factually incorrect.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
I mean, yes. But the post being replied to is about Rubio.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
www.nytimes.com/interactive/...
nytimes.com
Read the Memo (Published 2025)
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
www.impactcounter.com/dashboard?vi...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
www.thelancet.com/article/S014...
thelancet.com
Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis
USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the a...
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
Probably close to 750,000 deaths in the first year, with half a million of those being children. And that's just deaths. Probably 9M excess malaria cases, etc.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
Hasn't happened yet and my bet is it won't.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
I've heard Marco Rubio called many things but this is the first time I've heard him called "West Coast."
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 19h
He was an huge piece of shit. He was also a major proponent of the Weaver stance, which was, for most handgun users who faced actual situations of lethal peril, exactly the wrong technique. But yes, absurdly influential.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 20h
That's in no small part because, until pretty recently, the electorate was overwhelmingly in favor of capital punishment. It still is the majority position.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 20h
Good writeup by @boghuma.bsky.social: bktitanji.substack.com/p/how-unethi...
bktitanji.substack.com
How Unethical Research Seeds Medical Mistrust
The absence of equipoise can turn research into harm
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 20h
No. The design of this trial is wildly unethical.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 20h
The modern version of the vaccine, which is manufactured in yeast cells, was developed just downstairs from my laboratory at UW, by Ben Hall and his collaborators. It has saved *millions* of lives. pubmed.ncbi.nlm.nih.gov/7045698/
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Reposted by Alex Merz 🇺🇸🇨🇦🇺🇦
James @gravitysra1nbow.bsky.social · 21h
AHHHHHHH THE ONLY REASON HE EVEN STAYS TO DIE AT TROY IN THE ILIAD IS TO AVENGE PATROCLUS. IT'S A POEM ABOUT HIS RAGE. THE OPENING LINES ARE PRETTY CLEAR WHY CAN'T A SINGLE DEFENDER OF WESTERN CIVILIZATION READ A SINGLE THING FROM THE WESTERN CANON AHHHHHHHHHHHHHHHHHHHH
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 21h
People who recklessly endanger their kids should not be allowed to do so.
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