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melaniearndt.bsky.social

@melaniearndt.bsky.social
30 followers 50 following 2 posts
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melaniearndt.bsky.social @melaniearndt.bsky.social · 28/08/2025
The second part of my PhD work is now out in NSMB! 🚨✨ We explored how IST2, a known ER–plasma membrane tether in S. cerevisiae, facilitates lipid transfer at membrane contact sites. Check it out: www.nature.com/articles/s41...
nature.com
Structural basis for lipid transport at membrane contact sites by the IST2–OSH6 complex - Nature Structural & Molecular Biology
IST2 serves as a tether between the endoplasmic reticulum and the plasma membrane in yeast. Here, Arndt et al. interrogate its interaction with OSH6, revealing that the two proteins remain associated ...
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Reposted by @melaniearndt.bsky.social
Dutzler lab @dutzlerlab.bsky.social · 27/06/2025
🚨 Anastasiia’s latest paper is out! We discovered that TTYH2 and ApoE bind in the endosomal lumen, where TTYH2 then facilitates lipid transfer from ApoE into the endosomal membrane. Check it out now in Nature: www.nature.com/articles/s41...
nature.com
Interactions between TTYH2 and APOE facilitate endosomal lipid transfer - Nature
The Tweety homologue TTYH2 is identified as the lipid transfer mediator for APOE-containing lipoproteins.
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