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Mehran Dastmalchi

@mehran-plantsci.bsky.social
58 followers 83 following 18 posts

Assistant Professor at the University of Toronto, Scarborough

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Mehran Dastmalchi @mehran-plantsci.bsky.social · 15/04/2026
Lab is all registered and ready to go! (Final day of early bird today 🕐🐦.)
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 03/03/2026
Newly out from my lab! Here, we described the utility & the metabolic impact of molecular transporters in engineered 🧬 yeast, producing the anti-hypertensive drug, ajmalicine. 💊@utscbiology.bsky.social @utsc.utoronto.ca www.sciencedirect.com/science/arti...
sciencedirect.com
Heterologous expression of CrMATE1 increases flux of intermediates in monoterpenoid indole alkaloid pathway
Catharanthus roseus is the source of many pharmacologically valuable monoterpenoid indole alkaloids (MIAs), yet their low abundance can often constrai…
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 18/02/2026
Overnight whole plasmid, whole genome, etc. DNA sequencing is now available @utsc.utoronto.ca. Look at our beautiful @flowgenomics.bsky.social dropbox 🇨🇦🧬
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Reposted by Mehran Dastmalchi
Maite Colinas @maitecolinas.bsky.social · 10/02/2026
In our latest preprint we report the unexpected discovery of Epi-STR, an R-stereoselective ortholog of the S-selective canonical Strictosidine synthases (STRs). Found in the rather obscure plant Pogonopus specious. This work was led by my stellar student Clara Morweiser! #natprod #PlantScience
Scheme showing the Pictet-Spengler reaction between tryptamine and a secoiridoid by canonical S-selective STRs compared to the newly discovered Epi-STR. On the right a photo of the pink flowers of Pogonopus speciosus. Photo taken by Eva Rothe.
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 05/02/2026
We have 5 new undergrads working in the lab this semester - Camille, Gabriel, Eshal, and Dilaksha (Fanfan's team!) and Abinaya (working with Lorena). See their profiles here: www.dastmalchilab.com/lab/people
dastmalchilab.com
People — Dastmalchi Lab
Assistant ProfessorDepartment of Biological Sciences - University of Toronto, Scarborough
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 12/01/2026
Our lab is attending Plant Bio 2026 in Ottawa! See you all July 18-22! @aspbofficial.bsky.social @cspbscbv.bsky.social
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 09/01/2026
Protein–Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis | ACS Chemical Biology pubs.acs.org/doi/full/10....
pubs.acs.org
Protein–Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis
Biosynthetic pathways of specialized metabolites utilize protein–protein interactions (PPIs) to facilitate metabolic flux and sequester reactive intermediates. The monoterpene indole alkaloid pathway ...
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 15/12/2025
#books I read in 2025: Not as many strong recommendations to give this year. Vineland was a slog. Latronico's Perfection was a tasty palate cleanser.
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 11/12/2025
Dastmalchi Lab 2025 / Holiday Party🎄
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 19/11/2025
In 1996, almost thirty years ago, Stephan Clemens & Wolfgang Barz described a methylenedioxy bridge formation reaction, converting calycosin to pseudobaptigenin. Today, we have identified the enzyme catalyst from red clover! 🍀 @UTSC @UtscBiology www.biorxiv.org/cgi/content/...
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 30/10/2025
Such a neat idea for a special collection! New insights / side projects, consider submitting here.
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 28/10/2025
Went for a run last week along the scenic Ma Moosh Ka Win Valley Trail @utsc.utoronto.ca -- that starts behind our lab and can be followed to the lake! -- and made a friend.
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Reposted by Mehran Dastmalchi
Maeda Plant Metabolism Lab @hiroshi-maeda.bsky.social · 23/10/2025
The Phytochemical Society of North America (PSNA) is now accepting nominations for the 2026 Arthur Neish Young Investigator Award and applications for the TPJ-PSNA Early Career Award! The deadline is January 30, 2026. Find the guideline at: www.psna-online.org/awards #PSNA #PlantMetabolism
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Reposted by Mehran Dastmalchi
The Plant Cell @theplantcell.bsky.social · 23/10/2025
Salicylic acid biosynthesis via the PAL pathway requires benzaldehyde synthase and a benzyl salicylate-specific esterase (Dawei Ma, Harley Gordon, Rashid Nazir, Jeremy E Wulff, C Peter Constabel) doi.org/10.1093/plce... #PlantScience @aspbofficial
doi.org
Salicylic acid biosynthesis via the PAL pathway requires benzaldehyde synthase and a benzyl salicylate-specific esterase
Salicylic acid biosynthesis in seed plants requires the production of benzyl benzoate and benzyl salicylate, which is subsequently cleaved by an esterase.
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 22/10/2025
Iconic smokestacks / Andrews Building @utsc.utoronto.ca.
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 22/10/2025
Interesting, rather than juglone, 2Z-decaprenol isolated as a strong allelochemical from Juglans mandshurica via bioassay-guided fractionation. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Allelochemical from Leaves of Juglans mandshurica Maxim. And Its Transcriptomic Effects in Plants
Weeds have a significant effect on agricultural productivity; thus, sustainable herbicide alternatives are necessary. Inspired by natural processes where bioactive compounds from fallen leaves inhibit...
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 10/10/2025
I have tried and failed to finish reading László Krasznahorkai's Sátántangó on more than one occasion. Clearly #Nobel worthy.
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Reposted by Mehran Dastmalchi
Danve Castroverde @danvec.bsky.social · 03/10/2025
The 2025 #CSPB_ERM conference website is now ONLINE! LINK: event.fourwaves.com/erm2025 Early registration: Oct. 24 Regular registration: Oct. 25-Nov. 12 Abstract deadline for oral/poster presentations: Oct. 24 Student/postdoc registration fees are heavily discounted. See you soon!
event.fourwaves.com
Canadian Society of Plant Biologists - Eastern Regional 2025 Meeting
Fourwaves - Canadian Society of Plant Biologists - Eastern Regional 2025 Meeting
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Reposted by Mehran Dastmalchi
The Plant Journal @theplantjournal.bsky.social · 29/09/2025
📢Announcement! The call for 𝐓𝐏𝐉 𝐅𝐞𝐥𝐥𝐨𝐰𝐬𝐡𝐢𝐩 𝐬𝐜𝐡𝐞𝐦𝐞 𝐟𝐨𝐫 𝟐𝟎𝟐𝟓 is now open! 🌟 It is designed to offer support and mentorship to researchers transitioning from post-doctoral scientists to principal investigators Info: 👉http://onlinelibrary.wiley.com/page/journal/1365313x/homepage/TPJ-fellowships & in 🧵
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Reposted by Mehran Dastmalchi
Maeda Plant Metabolism Lab @hiroshi-maeda.bsky.social · 12/09/2025
Our new study in Nature Plants maps how "multi-tasking" enzymes in plants transfer nitrogen, a key step toward improving crop N use efficiency. 🌱 Big thanks to our collaborators from Max Planck, Hokkaido Univ, & MSU, and for support from @NSF and @DOE. Learn more: rdcu.be/eFOFN #PlantMetabolism
rdcu.be
Mapping multi-substrate specificity of Arabidopsis aminotransferases
Nature Plants - Systematic characterization of Arabidopsis aminotransferase family enzymes uncovered many previously unrecognized activities and revealed their multi-substrate specificity, aspects...
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Mehran Dastmalchi @mehran-plantsci.bsky.social · 11/09/2025
I'm here. New lab, new office. Back at @utoronto.ca where it all started (Class of 2029). Re-starting my research program on the gorgeous @utsc.utoronto.ca campus.
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