Reposted by Mathias Cobbaut
Excited to share our latest publication 🚨
We reveal insights into how a key protein kinase orchestrates cell polarity, uncovering unexpected molecular behaviours that shape this essential biological process!
Great work from everyone involved at the @crick.ac.uk and @polarityi3s.bsky.social
nature.com
Capture, mutual inhibition and release mechanism for aPKC–Par6 and its multisite polarity substrate Lgl - Nature Structural & Molecular Biology
Combining structural, biochemical, cellular and in vivo assays, the authors uncover the mechanism for capture and multisite phosphorylation of lethal (2) giant larvae by the atypical protein kinase C ...
