Colorectal cancer with peritoneal metastases has a particularly poor prognosis. In this KWF-funded project, you will investigate how glycan structures affect immune responses in peritoneal metastasis and whether glycan inhibition can restore anti-tumor immunity.

Tumour-reactive CD8+ T cells are enriched in functional clusters with tumour cells and/or antigen-presenting cells and can be isolated and expanded from clinical samples.

Background For decades, vast stretches of the genome were dismissed as non-functional ‘junk’. However, our group and others have revealed that these regions harbor numerous non-canonical open reading ...

Investigate whether local application in the lung can further enhance the efficacy of nanovaccines in generating lung-resident memory T cells.

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive B-cell non-Hodgkin lymphoma, often developing resistance to current treatments. De…