We use ultra high dimensional spectral cytometry coupled with machine learning assisted analytics to generate immune signatures predictive of IO outcomes.
We can also map out longitudinal immune trajectories towards severe vs non-severe adverse events.
aacrjournals.org/cancerimmuno...
aacrjournals.org
Abstract A002: Comprehensive blood profiling for immunotherapy outcome prediction and longitudinal immune trajectory characterisation
AbstractBackground:. Immune checkpoint inhibition (ICI) has revolutionised cancer care, but many patients do not mount anti-tumor activity and most develop autoimmune toxicity. Mechanisms and risk fac...