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Max Dudek

@maxdudek.bsky.social

PhD Candidate @ Penn 🧬 Genomics and Computational Bio 💻 orcid.org/0000-0001-8521-9543 Labs: @struangrant.bsky.social, Laura Almasy

Posts Replies Media

Max Dudek @maxdudek.bsky.social · 20/03/2026

I will be speaking about this work next week at the Probabilistic Modeling in Genomics conference in Berkeley on Thursday @ 11:30 am. If you’re attending, come and say hi!

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Max Dudek @maxdudek.bsky.social · 20/03/2026

We also present a simplified model of QTL discovery, suggesting that caQTL sensitivity more easily captures regulatory variants than eQTLs at constrained genes. Since GWAS hits are enriched at these genes, caQTLs can supplement eQTLs in interpreting the molecular mechanisms of trait heritability.

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Max Dudek @maxdudek.bsky.social · 20/03/2026

Excited to finally share my recent preprint with @struangrant.bsky.social! www.biorxiv.org/content/10.6... We collected chromatin accessibility QTLs (caQTLs) from 10 different studies and observed that they are less depleted at selectively constrained genes compared to eQTLs. 👇👇👇

biorxiv.org

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Max Dudek @maxdudek.bsky.social · 14/10/2025

I'll be at #ASHG25 this week! Check out my poster Wed 2:30-4:30, at 5071W. "Bridging the GWAS-eQTL colocalization gap with insights from caQTL analyses" with @struangrant.bsky.social and Laura Almasy

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Max Dudek @maxdudek.bsky.social · 29/08/2025

Most p-value explanations that I've come across focus only on the mechanical process of calculation, without telling students why they're doing it or how to interpret the results. So this video is me attempting to motivate the concept of hypothesis testing from first principles.

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Max Dudek @maxdudek.bsky.social · 29/08/2025

My foray into video creation! This is my entry into #SoME4, an annual exposition of math-explainers. A friendly introduction to hypothesis testing, with minimal math background required. www.youtube.com/watch?v=qEE0rzytHls

youtube.com

What is a p-value? #SoME4

YouTube video by Max Dudek

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Reposted by Max Dudek

Yun S. Song @yun-s-song.bsky.social · 06/06/2025

The 2026 Probabilistic Modeling in Genomics (ProbGen) meeting will be held at UC Berkeley, March 25-28, 2026. We have an amazing list of keynote speakers and session chairs: probgen2026.github.io Please help spread the news.

probgen2026.github.io

Home - ProbGen 2026

Your Site Description

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Max Dudek @maxdudek.bsky.social · 10/06/2025

Congrats!

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Reposted by Max Dudek

Struan Grant @struangrant.bsky.social · 05/06/2025

Check out @maxdudek.bsky.social paper on fpQTLs! www.cell.com/ajhg/fulltex...

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Max Dudek @maxdudek.bsky.social · 17/04/2025

With @struangrant.bsky.social, @ajhgnews.bsky.social Full text: authors.elsevier.com/a/1ky1DgeXDywz

authors.elsevier.com

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Max Dudek @maxdudek.bsky.social · 17/04/2025

Our new paper is out today in AJHG! We applied a "footprinting" algorithm to ATAC-seq data from 170 livers to find non-coding variants associated with TF binding. We show that these "footprint QTLs" (#fpQTLs) can fine-map GWAS loci at base-pair resolution. www.cell.com/ajhg/fulltex...

cell.com

Characterization of non-coding variants associated with transcription-factor binding through ATAC-seq-defined footprint QTLs in liver

Dudek et al. use chromatin accessibility data in liver from 170 human donors to measure transcription factor binding at genetic variants. They observed 809 variants associated with binding. Given bind...

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Reposted by Max Dudek

Hank Green @hankgreen.bsky.social · 22/11/2024

This is one of those videos that you could work on forever, but suddenly it felt very important to make it, so I finally did: www.youtube.com/watch?v=d8Pn...

youtube.com

Populism, Media Revolutions, and Our Terrible Moment

YouTube video by vlogbrothers

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Reposted by Max Dudek

Struan Grant @struangrant.bsky.social · 22/11/2024

Good to see @maxdudek.bsky.social on here now - here’s his recent preprint

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