iiinova — where your digital self keeps evolving

That's top shelf, Mr Metcalfe!

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Aus v Tur: that's as good a half of football as one could hope for.

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If it's the same incident I saw, yes.

I woke up in time for the equaliser.

Busy weekend. Football WC matches. WC MTB DH racing last night. Le Mans 24 hour currently. NASCAR this evening. And F1 (but who cares).

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I fell asleep it was so interesting.

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If they could connect the last pass better, they might be a few goals up.

Matt Padula @mattpadula.bsky.social · 13/06/2026

This US team will make the tournament infinitely more interesting. If they keep playing like that, they'll go deep in tournament. If Australia remembers how to finish moves, they'll likely win. 🫣

Matt Padula @mattpadula.bsky.social · 13/06/2026

And to keep the cup in here.... The result in Canada vs Bosnia was probably what was deserved. Entertaining football.

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Matt Padula @mattpadula.bsky.social · 13/06/2026

US were surprising. Beautiful attacking football and in complete control. Paraguay were pretty crap but because the US gave them zero opportunities. As an Australian, I am now worried about the upcoming match. Tomorrow's match with Turkey is now critical.

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Brian Phillips @brianphillips.lol · 28/05/2026

Here's the serious bit for anyone who'd rather skip the 4000 words of jokes

Because the truth is, tech doesn't have an image problem. It doesn't have a message problem. It has an intention problem. What's wrong with the axe murderer who broke into my house is not that he hasn't successfully persuaded me to buy into his narrative. What's wrong is that he's trying to kill me with an axe. Similarly, when you launch a product that's designed to put millions of people out of work, block access to sources of verifiable truth, replace human creativity with slop, and lower the barriers to every sort of atrocity, the problem isn't that you haven't told the public a good story about those things. The problem is that you are trying to do them. (
There are things in the world that are more important than money. The fact that you seem not to believe this, that you seem to think any motive beyond ruthless acquisitiveness is fake, dishonest, or childish, is the heart of your problem. Your attitude is not by any means unique to tech, but the

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Matt Padula @mattpadula.bsky.social · 25/05/2026

Getting increasingly pissed off at funding agencies, both government and philanthropy, NOT providing feedback on why applications are not successful. This should be mandatory for transparency and improvement. And it gives the impression that something is being hidden....🤔

Matt Padula @mattpadula.bsky.social · 23/05/2026

Yeah. If you are blindly trusting your reagents, you only have yourself to blame.

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Magnus Palmblad @magnuspalmblad.bsky.social · 22/05/2026

Companies selling faulty products by accident recall them and reimburse the customers. Some cost, some (temporary) loss in prestige perhaps. No one goes to jail. This is not the case here. This is more akin to the Theranos or VW emission scandals. And people did go to jail for these.

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Chris Ashwood @cashwood.proteaglyco.com · 21/05/2026

The Australian Academy of Science announced their 2026 fellows today, including Nicki Packer. "She is a pioneer in enabling, promoting and transforming glycoscience from an unrecognised niche research area into a high-impact international specialty field..." #glycotime science.org.au/about-us/aca...

science.org.au

Nicki Packer | Australian Academy of Science

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Proteomes MDPI @proteomesmdpi.bsky.social · 19/05/2026

Proteomes has announced the Top 20 Viewed Papers in 2025. You are welcome to take a look! 🧬🖥️🧪🥼🔬 www.mdpi.com/about/announ... #proteomes #proteomics #proteoforms

https://www.mdpi.com/2227-7382/13/1/12
https://www.mdpi.com/2227-7382/13/2/17
https://www.mdpi.com/2227-7382/13/1/3
https://www.mdpi.com/2227-7382/13/1/6
https://www.mdpi.com/2227-7382/13/2/24
https://www.mdpi.com/2227-7382/13/4/47
https://www.mdpi.com/2227-7382/13/3/26
https://www.mdpi.com/2227-7382/13/3/45
https://www.mdpi.com/2227-7382/13/1/11
https://www.mdpi.com/2227-7382/13/2/16
https://www.mdpi.com/2227-7382/13/2/25
https://www.mdpi.com/2227-7382/13/4/60
https://www.mdpi.com/2227-7382/13/4/53
https://www.mdpi.com/2227-7382/13/3/37
https://www.mdpi.com/2227-7382/13/2/19
https://www.mdpi.com/2227-7382/13/3/31
https://www.mdpi.com/2227-7382/13/1/9
https://www.mdpi.com/2227-7382/13/1/8
https://www.mdpi.com/2227-7382/13/2/20
https://www.mdpi.com/2227-7382/13/3/32

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Brett Phinney @ucdproteomics.bsky.social · 18/05/2026

It's that time of year again for are Annual proteomics chart course! Going on almost 20 years! Honestly it's a good class for those wanting to add proteomics to your research. And Proteomics really is the best Omics if I don't say so myself #proteomics #massspec #proteome #massspectrometry

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Chris Ashwood @cashwood.proteaglyco.com · 12/05/2026

I'm presenting at the 2026 Skyline User Group Meeting how RE-CID on a Stellar enables: - real-time N-glycan charge assignment - 10–100× signal gains over HCD - isomer-specific PRM quantitation across 5 orders of magnitude All exclusively on a nominal mass instrument with Skyline #glycotime

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Matt Padula @mattpadula.bsky.social · 11/05/2026

Piece of advice to students asking for my support for scholarship applications: asking FOUR days before the deadline will result in me declining to support you. 🤔

Matt Padula @mattpadula.bsky.social · 09/05/2026

My journal (Proteomes) has been badgering me about online symposiums. Are you volunteering to help organise one along these lines? I'm happy with awkward discussions.

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Matt Padula @mattpadula.bsky.social · 09/05/2026

Yeah. I'm struggling understanding whether the way DIA-NN output is further processed by others is leading to poor interpretations cause "bad" data is ignored in the quest for big numbers. The more I learn, the lazier I think people are. It's not the tech, it's poor understanding of the tech.

Matt Padula @mattpadula.bsky.social · 30/04/2026

I was surprised how much space was dedicated to 2D-PAGE and that it supports the process of Integrated Top Down Proteomics as a way of characterising proteoforms without stating it.

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Matt Padula @mattpadula.bsky.social · 17/04/2026

One of our systems was quoted as AUD $90K. We worked out a cheaper way.

Matt Padula @mattpadula.bsky.social · 04/04/2026

Or spectral library in case of DIA.

Matt Padula @mattpadula.bsky.social · 04/04/2026

The peptide with the variant is so low abundance it isn't detectable or give poor MSMS spectrum.

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Matt Padula @mattpadula.bsky.social · 04/04/2026

The variant isn't in the database so you don't find it cause the program doesn't know to look for it.

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Proteomes MDPI @proteomesmdpi.bsky.social · 20/03/2026

We are pleased to share this article published in Proteomes: Proteomics—The State of the Field: The Definition and Analysis of Proteomes Should Be Based in Reality, Not Convenience 🧬🖥️🧪🔬🥼 www.mdpi.com/2227-7382/12... #proteomes #proteomics #proteoform

mdpi.com

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PastelBio @pastelbio.bsky.social · 19/03/2026

Single-molecule peptide sequencing through reverse translation of peptides into DNA www.nature.com/artic... --- #proteomics #prot-paper

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Matt Padula @mattpadula.bsky.social · 13/03/2026

I wouldn't trust the opinions of two of the "experts" mentioned in that article. Charlatans. 😉

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Matt Padula @mattpadula.bsky.social · 13/03/2026

Today's top of my rolling list of people's stupidity are journal's that keep sending emails with the following as the title: Request for Permission to extend publication proposal You are asking permission to send something you have already sent, the actual email that this is the title. Morons.

Matt Padula @mattpadula.bsky.social · 08/03/2026

Be nice to others, respect others opinions, and don't profit at another person's expense.